Search Results - "Darcy, Christabelle J"

An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function by Darcy, Christabelle J, Davis, Joshua S, Woodberry, Tonia, McNeil, Yvette R, Stephens, Dianne P, Yeo, Tsin W, Anstey, Nicholas M

“…Both endothelial and immune dysfunction contribute to the high mortality rate in human sepsis, but the underlying mechanisms are unclear. In response to…”
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Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis by Davis, Joshua S, Darcy, Christabelle J, Yeo, Tsin W, Jones, Catherine, McNeil, Yvette R, Stephens, Dianne P, Celermajer, David S, Anstey, Nicholas M

“…Plasma concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, are raised in patients with chronic vascular…”
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HPLC analysis of asymmetric dimethylarginine, symmetric dimethylarginine, homoarginine and arginine in small plasma volumes using a Gemini-NX column at high pH by Jones, Catherine E., Darcy, Christabelle J., Woodberry, Tonia, Anstey, Nicholas M., McNeil, Yvette R.

“…There is increasing recognition of the clinical importance of endogenous nitric oxide synthase inhibitors in critical illness. This has highlighted the need…”
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Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome by Yeo, Tsin W, Lampah, Daniel A, Tjitra, Emiliana, Gitawati, Retno, Darcy, Christabelle J, Jones, Catherine, Kenangalem, Enny, McNeil, Yvette R, Granger, Donald L, Lopansri, Bert K, Weinberg, J Brice, Price, Ric N, Duffull, Stephen B, Celermajer, David S, Anstey, Nicholas M

“…Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is a predictor of mortality in critical illness. Severe malaria…”
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Recovery of Endothelial Function in Severe Falciparum Malaria: Relationship with Improvement in Plasma l-Arginine and Blood Lactate Concentrations by Yeo, Tsin W., Lampah, Daniel A., Gitawati, Retno, Tjitra, Emiliana, Kenangalem, Enny, McNeil, Yvette R., Darcy, Christabelle J., Granger, Donald L., Weinberg, J. Brice, Lopansri, Bert K., Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M.

“…Background. Severe malaria is characterized by microvascular obstruction, endothelial dysfunction, and reduced levels of l-arginine and nitric oxide (NO)…”
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Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients by Darcy, Christabelle J, Minigo, Gabriela, Piera, Kim A, Davis, Joshua S, McNeil, Yvette R, Chen, Youwei, Volkheimer, Alicia D, Weinberg, J Brice, Anstey, Nicholas M, Woodberry, Tonia

“…Impaired T cell function in sepsis is associated with poor outcome, but the mechanisms are unclear. In cancer, arginase-expressing myeloid derived suppressor…”
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Ex-vivo changes in amino acid concentrations from blood stored at room temperature or on ice: implications for arginine and taurine measurements by Davis, Joshua S, Darcy, Christabelle J, Piera, Kim, McNeil, Yvette R, Woodberry, Tonia, Anstey, Nicholas M

“…Determination of the plasma concentrations of arginine and other amino acids is important for understanding pathophysiology, immunopathology and nutritional…”
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Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria by Yeo, Tsin W, Lampah, Daniel A, Gitawati, Retno, Tjitra, Emiliana, Kenangalem, Enny, McNeil, Yvette R, Darcy, Christabelle J, Granger, Donald L, Weinberg, J Brice, Lopansri, Bert K, Price, Ric N, Duffull, Stephen B, Celermajer, David S, Anstey, Nicholas M

“…Severe falciparum malaria (SM) is associated with tissue ischemia related to cytoadherence of parasitized erythrocytes to microvascular endothelium and reduced…”
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Correction: Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome by Yeo, Tsin W., Lampah, Daniel A., Tjitra, Emiliana, Gitawati, Retno, Darcy, Christabelle J., Jones, Catherine, Kenangalem, Enny, McNeil, Yvette R., Granger, Donald L., Lopansri, Bert K., Weinberg, J. Brice, Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M.

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Increased plasma arginase activity in human sepsis: association with increased circulating neutrophils by Darcy, Christabelle J, Woodberry, Tonia, Davis, Joshua S, Piera, Kim A, McNeil, Yvette R, Chen, Youwei, Yeo, Tsin W, Weinberg, J Brice, Anstey, Nicholas M

“…The pathophysiology of sepsis is incompletely understood. Impaired bioavailability of L-arginine, the substrate for NO synthesis, is linked to sepsis severity,…”
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Sepsis-associated microvascular dysfunction measured by peripheral arterial tonometry: an observational study by Davis, Joshua S, Yeo, Tsin W, Thomas, Jane H, McMillan, Mark, Darcy, Christabelle J, McNeil, Yvette R, Cheng, Allen C, Celermajer, David S, Stephens, Dianne P, Anstey, Nicholas M

“…Sepsis has a high mortality despite advances in management. Microcirculatory and endothelial dysfunction contribute to organ failure, and better tools are…”
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Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome: e1000868 by Yeo, Tsin W, Lampah, Daniel A, Tjitra, Emiliana, Gitawati, Retno, Darcy, Christabelle J, Jones, Catherine, Kenangalem, Enny, McNeil, Yvette R, Granger, Donald L, Lopansri, Bert K, Weinberg, J Brice, Price, Ric N, Duffull, Stephen B, Celermajer, David S, Anstey, Nicholas M

“…Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is a predictor of mortality in critical illness. Severe malaria…”
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MAM 2008 Poster Abstracts by Yeo, Tsin W., Lampah, Daniel A., Gitawati, Retno, Tjitra, Emiliana, Kenangalem, Enny, McNeil, Yvette R., Darcy, Christabelle J., Granger, Donald L., Weinberg, J. Brice, Lopansri, Bert K., Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M.

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