Search Results - "Darchen, F."

The experiences of pediatric nurses deployed to adult COVID-19 wards by Darchen, F., Audouin, H., Berger, M., Juin-Leonard, V.

“…The coronavirus pandemic created an unprecedented deployment of health professionals. The objective of this study was to describe the experiences of pediatric…”
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Multiple aspects of Rab protein action in the secretory pathway: Focus on Rab3 and Rab6 by Darchen, François, Goud, Bruno

“…Rab proteins form the largest branch of the Ras superfamily of GTPases. They are localized to the cytoplasmic face of organelles and vesicles involved in the…”
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Undergraduate nursing education reform in France: from vocational to academic programmes by Debout, C., Chevallier-Darchen, F., Petit dit Dariel, O., Rothan-Tondeur, M.

“…DEBOUT C., CHEVALLIER‐DARCHEN F., PETIT DIT DARIEL O. & ROTHAN‐TONDEUR M. (2012) Undergraduate nursing education reform in France: from vocational to academic…”
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Distinct role of Rab3A and Rab3B in secretory activity of rat melanotrophs by Rupnik, M, Kreft, M, Nothias, F, Grilc, S, Bobanovic, L K, Johannes, L, Kiauta, T, Vernier, P, Darchen, F, Zorec, R

“…Members of the Rab3 (A-D) subfamily of small GTPases are believed to play a key role in regulated exocytosis. These proteins share approximately 80% identity…”
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The GTPase Rab3a negatively controls calcium‐dependent exocytosis in neuroendocrine cells by Johannes, L., Lledo, P.M., Roa, M., Vincent, J.D., Henry, J.P., Darchen, F.

“…There is accumulating evidence that small GTPases of the rab family regulate intracellular vesicle traffic along biosynthetic and endocytotic pathways in…”
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Association of the GTP-Binding Protein Rab3A with Bovine Adrenal Chromaffin Granules by Darchen, Francois, Zahraoui, Ahmed, Hammel, Frederic, Monteils, Marie-Pierre, Tavitian, Armand, Scherman, Daniel

“…The Rab3A protein belongs to a large family of small GTP-binding proteins that are present in eukaryotic cells and that share amino acid identities with the…”
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Biochemical Characterization of Rab3-GTPase-activating Protein Reveals a Mechanism Similar to That of Ras-GAP by Clabecq, Aude, Henry, Jean-Pierre, Darchen, François

“…Small G proteins of the Rab family are regulators of intracellular vesicle traffic. Their intrinsic rate of GTP hydrolysis is very low but is enhanced by…”
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Physical techniques for the study of exocytosis in isolated cells by Henry, J.P., Darchen, F., Cribier, S.

“…Membrane traffic is an important aspect of cell biology which implies shuttle vesicles and multiple binding/fusion events. In spite of rapid progress at the…”
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Ketanserin binds to the monoamine transporter of chromaffin granules and of synaptic vesicles by Darchen, F, Scherman, D, Laduron, P M, Henry, J P

“…[3H]Ketanserin binding studies were performed on purified chromaffin granule membranes. Binding was found to occur on one class of sites and was temperature…”
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Reserpine binding to chromaffin granules suggests the existence of two conformations of the monoamine transporter by Darchen, Francois, Scherman, Daniel, Henry, Jean Pierre

“…The binding of [3H]reserpine ([3H]RES) to purified bovine chromaffin granule membranes has been studied at low membrane concentration. Saturation isotherms…”
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Quantitative autoradiography of the rat brain vesicular monoamine transporter using the binding of [3H]dihydrotetrabenazine and 7-amino-8-[125I]iodoketanserin by Darchen, F, Masuo, Y, Vial, M, Rostene, W, Scherman, D

“…The binding of [3H]dihydrotetrabenazine, a specific ligand of the monoamine transporter present on serotonin and catecholamine synaptic vesicles, was studied…”
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Myosin Va Mediates Docking of Secretory Granules at the Plasma Membrane by Desnos, Claire, Huet, Sebastien, Fanget, Isabelle, Chapuis, Catherine, Bottiger, Caroline, Racine, Victor, Sibarita, Jean-Baptiste, Henry, Jean-Pierre, Darchen, Francois

“…Myosin Va (MyoVa) is a prime candidate for controlling actin-based organelle motion in neurons and neuroendocrine cells. Its function in secretory granule (SG)…”
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Role of Rab3a in neurotransmitter and hormone release: a discussion of recent data by Henry, J P, Johannes, L, Dousseau, F, Poulain, B, Darchen, F

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Rab27A and Its Effector MyRIP Link Secretory Granules to F-Actin and Control Their Motion Towards Release Sites by Desnos, Claire, Schonn, Jean-Sébastien, Huet, Sébastien, Tran, Viet Samuel, El-Amraoui, Aziz, Raposo, Graça, Fanget, Isabelle, Chapuis, Catherine, Ménasché, Gaël, Geneviève de Saint Basile, Petit, Christine, Cribier, Sophie, Henry, Jean-Pierre, Darchen, François

“…The GTPase Rab27A interacts with myosin-VIIa and myosin-Va via MyRIP or melanophilin and mediates melanosome binding to actin. Here we show that Rab27A and…”
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Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction by Giovedì, Silvia, Darchen, François, Valtorta, Flavia, Greengard, Paul, Benfenati, Fabio

“…Synapsins, a family of neuron-specific phosphoproteins that play an important role in the regulation of synaptic vesicle trafficking and neurotransmitter…”
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MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes by El-Amraoui, Aziz, Schonn, Jean-Sébastien, Küssel-Andermann, Polonca, Blanchard, Stéphane, Desnos, Claire, Henry, Jean-Pierre, Wolfrum, Uwe, Darchen, François, Petit, Christine

“…Defects of the myosin VIIa motor protein cause deafness and retinal anomalies in humans and mice. We report on the identification of a novel…”
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Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals by Giovedì, Silvia, Vaccaro, Paola, Valtorta, Flavia, Darchen, François, Greengard, Paul, Cesareni, Gianni, Benfenati, Fabio

“…Synapsins, a family of neuron-specific phosphoproteins, have been demonstrated to regulate the availability of synaptic vesicles for exocytosis by binding to…”
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1-Methyl-4-phenylpyridinium is a substrate of the vesicular monoamine uptake system of chromaffin granules by Scherman, D, Darchen, F, Desnos, C, Henry, J P

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Subcellular distribution and function of Rab3A, B, C, and D isoforms in insulin-secreting cells by Iezzi, M, Escher, G, Meda, P, Charollais, A, Baldini, G, Darchen, F, Wollheim, C B, Regazzi, R

“…Insulin-secreting cells express four GTPases of the Rab3 family. After separation of extracts of INS-1 cells on a sucrose density gradient, the bulk of the A,…”
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Partial Protection against Botulinum B Neurotoxin-Induced Blocking of Exocytosis by a Potent Inhibitor of Its Metallopeptidase Activity by Anne, Christine, Turcaud, Serge, Blommaert, Armand G.S, Darchen, François, Johnson, Eric A, Roques, Bernard P

“…Clostridium botulinum neurotoxins (BoNTs) cause botulism, which is characterized by a flaccid paralysis, through inhibition of acetylcholine release by…”
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