Search Results - "Darby, S J"
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Validation of a genomic classifier that predicts metastasis following radical prostatectomy in an at risk patient population
Published in The Journal of urology (01-12-2013)“…Patients with locally advanced prostate cancer after radical prostatectomy are candidates for secondary therapy. However, this higher risk population is…”
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Ciliary Neurotrophic Factor (CNTF) for Human Retinal Degeneration: Phase I Trial of CNTF Delivered by Encapsulated Cell Intraocular Implants
Published in Proceedings of the National Academy of Sciences - PNAS (07-03-2006)“…Neurotrophic factors are agents with a promising ability to retard progression of neurodegenerative diseases and are effective in slowing photoreceptor…”
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Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer: An Ancillary Study of the NRG/RTOG 9601 Randomized Clinical Trial
Published in JAMA oncology (01-04-2021)“…Decipher (Decipher Biosciences Inc) is a genomic classifier (GC) developed to estimate the risk of distant metastasis (DM) after radical prostatectomy (RP) in…”
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Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images
Published in JAMA network open (01-03-2019)“…Proper evaluation of the performance of artificial intelligence techniques in the analysis of digitized medical images is paramount for the adoption of such…”
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Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis
Published in Gut (01-04-1999)“…BACKGROUND The pathogenesis of pancreatic fibrosis is unknown. In the liver, stellate cells play a major role in fibrogenesis by synthesising increased amounts…”
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Impact of Decipher on use of post‐operative radiotherapy: Individual patient analysis of two prospective registries
Published in BJUI compass (01-07-2021)“…Objective To assess the association between Genomic Classifier (GC)‐risk group and post‐radical prostatectomy treatment in clinical practice. Methods Two…”
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Usefulness of the Atrial Emptying Fraction to Predict Maintenance of Sinus Rhythm After Direct Current Cardioversion for Atrial Fibrillation
Published in The American journal of cardiology (01-11-2016)“…Abstract Atrial volumes indexed to body surface area (AVI) are robust predictors of non-valvular atrial fibrillation (AF) recurrence after direct current…”
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Evaluation of the Age-Related Eye Disease Study Clinical Lens Grading System: AREDS Report No. 31
Published in Ophthalmology (Rochester, Minn.) (01-11-2010)“…To examine the grading (interrater) reliability of the Age-Related Eye Disease Study (AREDS) Clinical Lens Grading System (ARLNS). Evaluation of diagnostic…”
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The Effect of Lutein and Zeaxanthin Supplementation on Metabolites of These Carotenoids in the Serum of Persons Aged 60 or Older
Published in Investigative ophthalmology & visual science (01-12-2006)“…To investigate the effect of lutein supplementation at doses of 2.5, 5.0, and 10 mg/d for 6 months on distribution of these carotenoids and their metabolites…”
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Dose-Ranging Study of Lutein Supplementation in Persons Aged 60 Years or Older
Published in Investigative ophthalmology & visual science (01-12-2006)“…To examine the dose-response relationship between oral lutein supplementation and serum lutein concentrations in persons aged 60 years and older, with or…”
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A randomized, placebo‐controlled, double‐masked clinical trial of etanercept for the treatment of uveitis associated with juvenile idiopathic arthritis
Published in Arthritis and rheumatism (15-02-2005)“…Objective To investigate the safety and efficacy of etanercept in the treatment of uveitis associated with juvenile idiopathic arthritis (JIA). Methods…”
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Late Outgrowth Endothelial Progenitor Cells in Patients with Age-Related Macular Degeneration
Published in Investigative ophthalmology & visual science (01-06-2008)“…To evaluate the feasibility of isolating and expanding endothelial progenitor cells (EPCs), in the form of late outgrowth endothelial progenitor cells (OECs),…”
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Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2000)“…Background & Aims: Activated pancreatic stellate cells have recently been implicated in pancreatic fibrogenesis. This study examined the role of pancreatic…”
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New clean energy communities in polycentric settings: Four avenues for future research
Published in Energy research & social science (01-12-2021)“…Given the gaps between EU ambitions regarding energy community development and the current reality of clean energy communities in Europe, we explore a research…”
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Genomic Classifier Performance in Intermediate-Risk Prostate Cancer: Results From NRG Oncology/RTOG 0126 Randomized Phase 3 Trial
Published in International journal of radiation oncology, biology, physics (01-10-2023)“…Intermediate-risk prostate cancer is a heterogeneous disease state with diverse treatment options. The 22-gene Decipher genomic classifier (GC) retrospectively…”
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Decipher test impacts decision making among patients considering adjuvant and salvage treatment after radical prostatectomy: Interim results from the Multicenter Prospective PRO‐IMPACT study
Published in Cancer (01-08-2017)“…BACKGROUND Patients with prostate cancer and their providers face uncertainty as they consider adjuvant radiotherapy (ART) or salvage radiotherapy (SRT) after…”
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Impact of Patient Use of an Online Patient Portal on Diabetes Outcomes
Published in Canadian journal of diabetes (01-02-2014)“…Abstract Objective To assess the effect of patient use of an online patient portal on diabetes outcomes. Methods Patients included were those with diabetes who…”
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Impact of a genomic classifier of metastatic risk on postoperative treatment recommendations for prostate cancer patients: a report from the DECIDE study group
Published in Oncotarget (01-04-2013)“…Only a minority of prostate cancer patients with adverse pathology and biochemical recurrence (BCR) post radical prostatectomy (RP) experience metastasis and…”
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A Crossover Design for Comparative Efficacy: A 36-Week Randomized Trial of Bevacizumab and Ranibizumab for Diabetic Macular Edema
Published in Ophthalmology (Rochester, Minn.) (01-04-2016)“…To investigate the comparative efficacy of bevacizumab (Avastin) and ranibizumab (Lucentis; both Genentech, Inc, South San Francisco, CA) for diabetic macular…”
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Right Atrial Volume Is Superior to Left Atrial Volume for Prediction of Atrial Fibrillation Recurrence After Direct Current Cardioversion
Published in Canadian journal of cardiology (2015)“…Abstract Background The value of right atrial volume as a predictor for recurrence of atrial fibrillation (AF) after direct current cardioversion (DCCV) is…”
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