Search Results - "Darbon, Pascal"
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Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons
Published in Nature neuroscience (01-09-2020)“…Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant brain regions have been extensively studied, OT neuron…”
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A Nonpeptide Oxytocin Receptor Agonist for a Durable Relief of Inflammatory Pain
Published in Scientific reports (20-02-2020)“…Oxytocin possesses several physiological and social functions, among which an important analgesic effect. For this purpose, oxytocin binds mainly to its unique…”
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Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury
Published in Nature Medicine (01-03-2010)“…Muscle spasticity is a major problem for individuals with SCI. Now, Laurent Vinay and his colleagues report that downregulation of the potassium-chloride…”
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Editorial: Molecular neurobiology of chronic pain: pharmacological and non-pharmacological approaches in animal models
Published in Frontiers in molecular neuroscience (16-09-2024)Get full text
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An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats
Published in Nature communications (24-02-2023)“…The hypothalamic neuropeptide oxytocin (OT) exerts prominent analgesic effects via central and peripheral action. However, the precise analgesic pathways…”
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Anti-Hyperalgesic Properties of Menthol and Pulegone
Published in Frontiers in pharmacology (30-11-2021)“…Menthol, the main monoterpene found in L. ( ) is known to modulate nociceptive threshold and is present in different curative preparations that reduce sensory…”
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Spinal cellular and network properties modulate pain perception
Published in BIO web of conferences (2016)“…Through the example the modulation of pain perception by a steroid hormone, I’m going to show you a multiscale interaction between two systems of an organism…”
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The Role of Oxytocin in Abnormal Brain Development: Effect on Glial Cells and Neuroinflammation
Published in Cells (Basel, Switzerland) (02-12-2022)“…The neonatal period is critical for brain development and determinant for long-term brain trajectory. Yet, this time concurs with a sensitivity and risk for…”
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Antinociceptive Action of Oxytocin Involves Inhibition of Potassium Channel Currents in Lamina Ii Neurons of the Rat Spinal Cord
Published in Molecular pain (12-11-2009)“…Background Growing evidence in the literature shows that oxytocin (OT) has a strong spinal anti-nociceptive action. Oxytocinergic axons originating from a…”
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10
Calcium imaging and BAPTA loading of amygdala astrocytes in mouse brain slices
Published in STAR protocols (18-03-2022)“…Astrocytes are glial cells that exhibit calcium signaling-mediated activity. Here, we present a protocol to monitor and manipulate astrocyte calcium activity…”
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Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice in vivo
Published in Frontiers in oncology (21-02-2020)“…Tamoxifen is used to treat breast cancer and cancer recurrences. After administration, tamoxifen is converted into two more potent antitumor compounds,…”
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Lithium reverses mechanical allodynia through a mu opioid-dependent mechanism
Published in Molecular pain (01-01-2018)“…Abstract Background Lithium is widely used to treat bipolar disorders and displays mood stabilizing properties. In addition, lithium relieves painful cluster…”
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Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms
Published in Pain (Amsterdam) (31-10-2008)“…Fast Inhibitory controls mediated by glycine (GlyRs) and GABAA receptors (GABAARs) play an important role to prevent the apparition of pathological pain…”
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Mechanisms controlling bursting activity induced by disinhibition in spinal cord networks
Published in The European journal of neuroscience (01-02-2002)“…Disinhibition reliably induces regular synchronous bursting in networks of spinal interneurons in culture as well as in the intact spinal cord. We have…”
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Contributions of NMDA receptors to network recruitment and rhythm generation in spinal cord cultures
Published in The European journal of neuroscience (01-02-2004)“…N‐methyl‐d‐aspartic acid (NMDA) receptors are implicated in fictive locomotion; however, their precise role there is not clear. In cultures of dissociated…”
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INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons
Published in The European journal of neuroscience (01-08-2004)“…We have shown previously that rhythm generation in disinhibited spinal networks is based on intrinsic spiking, network recruitment and a network refractory…”
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17
Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents
Published in Nature neuroscience (01-04-2021)“…Oxytocin (OT) orchestrates social and emotional behaviors through modulation of neural circuits. In the central amygdala, the release of OT modulates…”
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A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System
Published in Neuron (Cambridge, Mass.) (03-07-2019)“…Oxytocin (OT) release by axonal terminals onto the central nucleus of the amygdala exerts anxiolysis. To investigate which subpopulation of OT neurons…”
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Contribution of Persistent Sodium Current to Locomotor Pattern Generation in Neonatal Rats
Published in Journal of neurophysiology (01-08-2007)“…Laboratoire de Plasticité et Physio-Pathologie de la Motricité, Unité Mixte de Recherche 6196, Centre National de la Recherche Scientifique, Aix-Marseille…”
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Favouring inhibitory synaptic drive mediated by GABA(A) receptors in the basolateral nucleus of the amygdala efficiently reduces pain symptoms in neuropathic mice
Published in The European journal of neuroscience (01-04-2016)“…Pain is an emotion and neuropathic pain symptoms are modulated by supraspinal structures such as the amygdala. The central nucleus of the amygdala is often…”
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