Search Results - "Darbon, Pascal"

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    A Nonpeptide Oxytocin Receptor Agonist for a Durable Relief of Inflammatory Pain by Hilfiger, Louis, Zhao, Qian, Kerspern, Damien, Inquimbert, Perrine, Andry, Virginie, Goumon, Yannick, Darbon, Pascal, Hibert, Marcel, Charlet, Alexandre

    Published in Scientific reports (20-02-2020)
    “…Oxytocin possesses several physiological and social functions, among which an important analgesic effect. For this purpose, oxytocin binds mainly to its unique…”
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    Journal Article
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    Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury by Vinay, Laurent, Boulenguez, Pascale, Liabeuf, Sylvie, Bos, Rémi, Bras, Hélène, Jean-Xavier, Céline, Brocard, Cécile, Stil, Aurélie, Darbon, Pascal, Cattaert, Daniel, Delpire, Eric, Marsala, Martin

    Published in Nature Medicine (01-03-2010)
    “…Muscle spasticity is a major problem for individuals with SCI. Now, Laurent Vinay and his colleagues report that downregulation of the potassium-chloride…”
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    Anti-Hyperalgesic Properties of Menthol and Pulegone by Hilfiger, Louis, Triaux, Zélie, Marcic, Christophe, Héberlé, Eléa, Emhemmed, Fathi, Darbon, Pascal, Marchioni, Eric, Petitjean, Hugues, Charlet, Alexandre

    Published in Frontiers in pharmacology (30-11-2021)
    “…Menthol, the main monoterpene found in L. ( ) is known to modulate nociceptive threshold and is present in different curative preparations that reduce sensory…”
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    Journal Article
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    Spinal cellular and network properties modulate pain perception by Darbon, Pascal

    Published in BIO web of conferences (2016)
    “…Through the example the modulation of pain perception by a steroid hormone, I’m going to show you a multiscale interaction between two systems of an organism…”
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    Journal Article Conference Proceeding
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    The Role of Oxytocin in Abnormal Brain Development: Effect on Glial Cells and Neuroinflammation by Knoop, Marit, Possovre, Marie-Laure, Jacquens, Alice, Charlet, Alexandre, Baud, Olivier, Darbon, Pascal

    Published in Cells (Basel, Switzerland) (02-12-2022)
    “…The neonatal period is critical for brain development and determinant for long-term brain trajectory. Yet, this time concurs with a sensitivity and risk for…”
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    Journal Article
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    Antinociceptive Action of Oxytocin Involves Inhibition of Potassium Channel Currents in Lamina Ii Neurons of the Rat Spinal Cord by Breton, Jean Didier, Poisbeau, Pierrick, Darbon, Pascal

    Published in Molecular pain (12-11-2009)
    “…Background Growing evidence in the literature shows that oxytocin (OT) has a strong spinal anti-nociceptive action. Oxytocinergic axons originating from a…”
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    Journal Article
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    Calcium imaging and BAPTA loading of amygdala astrocytes in mouse brain slices by Baudon, Angel, Clauss-Creusot, Etienne, Darbon, Pascal, Patwell, Ryan, Grinevich, Valery, Charlet, Alexandre

    Published in STAR protocols (18-03-2022)
    “…Astrocytes are glial cells that exhibit calcium signaling-mediated activity. Here, we present a protocol to monitor and manipulate astrocyte calcium activity…”
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    Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice in vivo by Gabel, Florian, Aubry, Anne-Sophie, Hovhannisyan, Volodya, Chavant, Virginie, Weinsanto, Ivan, Maduna, Tando, Darbon, Pascal, Goumon, Yannick

    Published in Frontiers in oncology (21-02-2020)
    “…Tamoxifen is used to treat breast cancer and cancer recurrences. After administration, tamoxifen is converted into two more potent antitumor compounds,…”
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    Lithium reverses mechanical allodynia through a mu opioid-dependent mechanism by Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Aouad, Maya, Maduna, Tando, Petit-Demoulière, Nathalie, Chavant, Virginie, Poisbeau, Pierrick, Darbon, Pascal, Charlet, Alexandre, Giersch, Anne, Parat, Marie-Odile, Goumon, Yannick

    Published in Molecular pain (01-01-2018)
    “…Abstract Background Lithium is widely used to treat bipolar disorders and displays mood stabilizing properties. In addition, lithium relieves painful cluster…”
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    Journal Article
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    Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms by Charlet, Alexandre, Lasbennes, François, Darbon, Pascal, Poisbeau, Pierrick

    Published in Pain (Amsterdam) (31-10-2008)
    “…Fast Inhibitory controls mediated by glycine (GlyRs) and GABAA receptors (GABAARs) play an important role to prevent the apparition of pathological pain…”
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    Journal Article
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    Mechanisms controlling bursting activity induced by disinhibition in spinal cord networks by Darbon, Pascal, Scicluna, Luke, Tscherter, Anne, Streit, Jürg

    Published in The European journal of neuroscience (01-02-2002)
    “…Disinhibition reliably induces regular synchronous bursting in networks of spinal interneurons in culture as well as in the intact spinal cord. We have…”
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    Journal Article
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    Contributions of NMDA receptors to network recruitment and rhythm generation in spinal cord cultures by Legrand, Jean-Christophe, Darbon, Pascal, Streit, Jürg

    Published in The European journal of neuroscience (01-02-2004)
    “…N‐methyl‐d‐aspartic acid (NMDA) receptors are implicated in fictive locomotion; however, their precise role there is not clear. In cultures of dissociated…”
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    INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons by Darbon, Pascal, Yvon, Cédric, Legrand, Jean-Christophe, Streit, Jürg

    Published in The European journal of neuroscience (01-08-2004)
    “…We have shown previously that rhythm generation in disinhibited spinal networks is based on intrinsic spiking, network recruitment and a network refractory…”
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    Journal Article
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    Contribution of Persistent Sodium Current to Locomotor Pattern Generation in Neonatal Rats by Tazerart, Sabrina, Viemari, Jean-Charles, Darbon, Pascal, Vinay, Laurent, Brocard, Frederic

    Published in Journal of neurophysiology (01-08-2007)
    “…Laboratoire de Plasticité et Physio-Pathologie de la Motricité, Unité Mixte de Recherche 6196, Centre National de la Recherche Scientifique, Aix-Marseille…”
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    Favouring inhibitory synaptic drive mediated by GABA(A) receptors in the basolateral nucleus of the amygdala efficiently reduces pain symptoms in neuropathic mice by Zeitler, Alexandre, Kamoun, Nisrine, Goyon, Stéphanie, Wahis, Jérôme, Charlet, Alexandre, Poisbeau, Pierrick, Darbon, Pascal

    Published in The European journal of neuroscience (01-04-2016)
    “…Pain is an emotion and neuropathic pain symptoms are modulated by supraspinal structures such as the amygdala. The central nucleus of the amygdala is often…”
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