Search Results - "Dar, Hamza"
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Comprehensive bioinformatics-based annotation and functional characterization of bovine chymosin protein revealed novel biological insights
Published in Food chemistry. Molecular sciences (30-07-2024)“…•Bovine chymosin is overall conserved.•We identified two peptidase active sites and a functional domain.•Secondary structure has many β-strands (44.27%) and…”
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Evaluating parental knowledge and attitudes toward childhood hearing loss: a cross-sectional study in Rawalpindi, Pakistan
Published in BMC pediatrics (15-11-2024)“…Background Childhood hearing loss poses a significant public health challenge in Pakistan, with prevalence rates over double the global average. Parental…”
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Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy in mice
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-06-2019)“…Painful diabetic neuropathy (PDN) is known to adversely affect psychosocial functioning by enhancing levels of anxiety and depression. This study was designed…”
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Association of Gestational Iron-deficiency Anemia with Antenatal Depression among Pregnant Women: A Case–control Study from Tertiary Care Hospitals, Lahore
Published in Dental research journal (01-01-2024)“…ABSTRACTObjective:The goal of this study is to investigate the potential association between gestational anemia and antenatal depression in pregnant…”
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Designing a multi-epitope vaccine against Mycobacteroides abscessus by pangenome-reverse vaccinology
Published in Scientific reports (27-05-2021)“…Mycobacteroides abscessus (Previously Mycobacterium abscessus ) is an emerging microorganism of the newly defined genera Mycobacteroides that causes mainly…”
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In Vitro Antioxidant, Anti-inflammatory, and In Vivo Anticolitis Effects of Combretin A and Combretin B on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
Published in Gastroenterology research and practice (07-11-2020)“…Combretum fragrans (Combretaceae) is a Cameroonian medicinal plant containing various secondary metabolites and traditionally used for the treatment of several…”
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Immunoinformatics-Aided Design and Evaluation of a Potential Multi-Epitope Vaccine against Klebsiella Pneumoniae
Published in Vaccines (Basel) (12-08-2019)“…is an opportunistic gram-negative bacterium that causes nosocomial infection in healthcare settings. Despite the high morbidity and mortality rate associated…”
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Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An In Silico Analysis
Published in Journal of immunology research (2020)“…The global health crisis caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, has resulted in a negative…”
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Immunoinformatics-Aided Analysis of RSV Fusion and Attachment Glycoproteins to Design a Potent Multi-Epitope Vaccine
Published in Vaccines (Basel) (24-08-2022)“…Respiratory syncytial virus (RSV) usually causes respiratory tract infections of upper airways in infants and young children. Despite recent medical advances,…”
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Anti-COVID-19 multi-epitope vaccine designs employing global viral genome sequences
Published in PeerJ (San Francisco, CA) (03-08-2020)“…The coronavirus SARS-CoV-2 is a member of the Coronaviridae family that has caused a global public health emergency. Currently, there is no approved treatment…”
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Pangenome Analysis of Mycobacterium tuberculosis Reveals Core-Drug Targets and Screening of Promising Lead Compounds for Drug Discovery
Published in Antibiotics (Basel) (01-11-2020)“…Tuberculosis, caused by Mycobacterium tuberculosis (M. tuberculosis), is one of the leading causes of human deaths globally according to the WHO TB 2019…”
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Genomic Investigation of Methicillin-Resistant Staphylococcus aureus ST113 Strains Isolated from Tertiary Care Hospitals in Pakistan
Published in Antibiotics (Basel) (17-09-2021)“…Methicillin-resistant Staphylococcus aureus (MRSA) is a multi-drug resistant and opportunistic pathogen. The emergence of new clones of MRSA in both healthcare…”
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Structural analysis and insight into Zika virus NS5 mediated interferon inhibition
Published in Infection, genetics and evolution (01-07-2017)“…The Zika virus outbreak in 2015–2016 is the largest of its kind for which WHO declared a Public Health Emergency of International Concerns. No FDA approved…”
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Revisiting the AIDS Epidemic in Pakistan: Where We Stand and What We Must Aim For
Published in AIDS research and human retroviruses (01-10-2017)“…Human immunodeficiency virus type 1 (HIV-1) is the major cause of acquired immunodeficiency syndrome (AIDS) in humans, where the immune system totally succumbs…”
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Whole-genome sequencing of a new sequence type (ST5352) strain of community-acquired methicillin-resistant Staphylococcus aureus from a hospital in Pakistan
Published in Journal of global antimicrobial resistance. (01-12-2019)“…Methicillin-resistant Staphylococcus aureus (MRSA) is an important drug-resistant pathogen causing a number of diseases, resulting in increased mortality…”
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Potential link between Complement 5a Receptor and mood disorders in mouse exposed to experimental malaria in utero
Published in Nigerian journal of physiological sciences (30-12-2017)“…In Africa, a large number of pregnancies are exposed to Plasmodium falciparum infection. The in-utero environment extremely influences childhood…”
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Low Complexity Bidirectional Equalization of Doubly Selective Channel Using BEM
Published in 2012 10th International Conference on Frontiers of Information Technology (01-12-2012)“…Low complexity equalization of doubly selective channels is motivated for real time processing of received signals to establish duplex communications…”
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