Search Results - "Daou, Salima"

Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes by Barbour, Haithem, Daou, Salima, Hendzel, Michael, Affar, El Bachir

“…Histone posttranslational modifications are key regulators of chromatin-associated processes including gene expression, DNA replication and DNA repair…”
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Functional characterization of a PROTAC directed against BRAF mutant V600E by Posternak, Ganna, Tang, Xiaojing, Maisonneuve, Pierre, Jin, Ting, Lavoie, Hugo, Daou, Salima, Orlicky, Stephen, Goullet de Rugy, Theo, Caldwell, Lauren, Chan, Kin, Aman, Ahmed, Prakesch, Michael, Poda, Gennady, Mader, Pavel, Wong, Cassandra, Maier, Stefan, Kitaygorodsky, Julia, Larsen, Brett, Colwill, Karen, Yin, Zhe, Ceccarelli, Derek F., Batey, Robert A., Taipale, Mikko, Kurinov, Igor, Uehling, David, Wrana, Jeff, Durocher, Daniel, Gingras, Anne-Claude, Al-Awar, Rima, Therrien, Marc, Sicheri, Frank

“…The RAF family kinases function in the RAS–ERK pathway to transmit signals from activated RAS to the downstream kinases MEK and ERK. This pathway regulates…”
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Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair by Yu, Helen, Pak, Helen, Hammond-Martel, Ian, Ghram, Mehdi, Rodrigue, Amélie, Daou, Salima, Barbour, Haithem, Corbeil, Luc, Hébert, Josée, Drobetsky, Elliot, Masson, Jean Yves, Noia, Javier M. Di, El Bachir Affar

“…The cellular response to highly genotoxic DNA double-strand breaks (DSBs) involves the exquisite coordination of multiple signaling and repair factors. Here,…”
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Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O by Mashtalir, Nazar, Daou, Salima, Barbour, Haithem, Sen, Nadine N., Gagnon, Jessica, Hammond-Martel, Ian, Dar, Haider H., Therrien, Marc, Affar, El Bachir

“…The tumor suppressor BAP1 interacts with chromatin-associated proteins and regulates cell proliferation, but its mechanism of action and regulation remain…”
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The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression by Yu, Helen, Mashtalir, Nazar, Daou, Salima, Hammond-Martel, Ian, Ross, Julie, Sui, Guangchao, Hart, Gerald W., Rauscher, Frank J., Drobetsky, Elliot, Milot, Eric, Shi, Yang, Affar, El Bachir

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer by Daou, Salima, Hammond-Martel, Ian, Mashtalir, Nazar, Barbour, Haithem, Gagnon, Jessica, Iannantuono, NicholasV.G., Nkwe, Nadine Sen, Motorina, Alena, Pak, Helen, Yu, Helen, Wurtele, Hugo, Milot, Eric, Mallette, Frédérick A., Carbone, Michele, Affar, El Bachir

“…The deubiquitinase (DUB) and tumor suppressor BAP1 catalyzes ubiquitin removal from histone H2A Lys-119 and coordinates cell proliferation, but how BAP1…”
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Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis by Uriarte, Maxime, Sen Nkwe, Nadine, Tremblay, Roch, Ahmed, Oumaima, Messmer, Clémence, Mashtalir, Nazar, Barbour, Haithem, Masclef, Louis, Voide, Marion, Viallard, Claire, Daou, Salima, Abdelhadi, Djaileb, Ronato, Daryl, Paydar, Mohammadjavad, Darracq, Anaïs, Boulay, Karine, Desjardins-Lecavalier, Nicolas, Sapieha, Przemyslaw, Masson, Jean-Yves, Sergeev, Mikhail, Kwok, Benjamin H., Hulea, Laura, Mallette, Frédérick A., Milot, Eric, Larrivée, Bruno, Wurtele, Hugo, Affar, El Bachir

“…Eukaryotic cells have evolved highly orchestrated protein catabolic machineries responsible for the timely and selective disposal of proteins and organelles,…”
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Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1 by Daou, Salima, Barbour, Haithem, Ahmed, Oumaima, Masclef, Louis, Baril, Caroline, Sen Nkwe, Nadine, Tchelougou, Daméhan, Uriarte, Maxime, Bonneil, Eric, Ceccarelli, Derek, Mashtalir, Nazar, Tanji, Mika, Masson, Jean-Yves, Thibault, Pierre, Sicheri, Frank, Yang, Haining, Carbone, Michele, Therrien, Marc, Affar, El Bachir

“…The tumor suppressor and deubiquitinase (DUB) BAP1 and its Drosophila ortholog Calypso assemble DUB complexes with the transcription regulators Additional sex…”
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The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis by Bottardi, Stefania, Mavoungou, Lionel, Pak, Helen, Daou, Salima, Bourgoin, Vincent, Lakehal, Yahia A, Affar, El Bachir, Milot, Eric

“…IKAROS is a critical regulator of hematopoietic cell fate and its dynamic expression pattern is required for proper hematopoiesis. In collaboration with the…”
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Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway by Daou, Salima, Mashtalir, Nazar, Hammond-Martel, Ian, Pak, Helen, Yu, Helen, Sui, Guangchao, Vogel, Jodi L, Kristie, Thomas M, Affar, El Bachir

“…Host Cell Factor 1 (HCF-1) plays critical roles in regulating gene expression in a plethora of physiological processes. HCF-1 is first synthesized as a…”
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An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes by Barbour, Haithem, Nkwe, Nadine Sen, Estavoyer, Benjamin, Messmer, Clémence, Gushul-Leclaire, Mila, Villot, Romain, Uriarte, Maxime, Boulay, Karine, Hlayhel, Sari, Farhat, Bassel, Milot, Eric, Mallette, Frédérick A., Daou, Salima, Affar, El Bachir

“…Ubiquitination is an important post-translational modification (PTM) that regulates a large spectrum of cellular processes in eukaryotes. Abnormalities in…”
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Undetectable histone O-GlcNAcylation in mammalian cells by Gagnon, Jessica, Daou, Salima, Zamorano, Natalia, Iannantuono, Nicholas V G, Hammond-Martel, Ian, Mashtalir, Nazar, Bonneil, Eric, Wurtele, Hugo, Thibault, Pierre, Affar, El Bachir

“…O-GlcNAcylation is a posttranslational modification catalyzed by the O-Linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) and reversed by O-GlcNAcase…”
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Vivid views of the PINK1 protein by Daou, Salima, Sicheri, Frank

“…Structures of an unusual enzymatic domain in PINK1 provide insights into how this protein regulates the function of organelles called mitochondria, and how…”
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Electron transfer dissociation (ETD): The mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein Host Cell Factor C1 by Myers, Samuel A., Daou, Salima, Affar, El Bachir, Burlingame, Al

“…The development of electron‐based, unimolecular dissociation MS, i.e. electron capture and electron transfer dissociation (ECD and ETD, respectively), has…”
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Vivid views of the PINK1 protein by Daou, Salima, Sicheri, Frank

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A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency by Daou, Salima, Talukdar, Manisha, Tang, Jinle, Dong, Beihua, Banerjee, Shuvojit, Li, Yize, Duffy, Nicole M., Ogunjimi, Abiodun A., Gaughan, Christina, Jha, Babal K., Gish, Gerald, Tavernier, Nicolas, Mao, Daniel, Weiss, Susan R., Huang, Hao, Silverman, Robert H., Sicheri, Frank

“…The oligoadenylate synthetase (OAS)–RNase L system is an IFN-inducible antiviral pathway activated by viral infection. Viral double-stranded (ds) RNA activates…”
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A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase by Sen Nkwe, Nadine, Daou, Salima, Uriarte, Maxime, Gagnon, Jessica, Iannantuono, Nicholas Victor, Barbour, Haithem, Yu, Helen, Masclef, Louis, Fernández, Erlinda, Zamorano Cuervo, Natalia, Mashtalir, Nazar, Binan, Loïc, Sergeev, Mikhail, Bélanger, François, Drobetsky, Elliot, Milot, Eric, Wurtele, Hugo, Costantino, Santiago, Affar, El Bachir

“…USP16 (also known as UBP-M) has emerged as a histone H2AK119 deubiquitylase (DUB) implicated in the regulation of chromatin-associated processes and cell cycle…”
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The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis: e1004827 by Bottardi, Stefania, Mavoungou, Lionel, Pak, Helen, Daou, Salima, Bourgoin, Vincent, Lakehal, Yahia A, Affar, El Bachir, Milot, Eric

“…IKAROS is a critical regulator of hematopoietic cell fate and its dynamic expression pattern is required for proper hematopoiesis. In collaboration with the…”
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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones by Masclef, Louis, Maxime, Uriarte, Ahmed, Oumaima, Sen Nkwe, Nadine, Barbour, Haithem, Iannantuono, Nicholas V G, Boubekeur, Amina, Daou, Salima, Affar, El Bachir

“…Ubiquitination is a post-translational modification that plays important roles in various signaling pathways and is notably involved in the coordination of…”
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Electron transfer dissociation ( ETD ): The mass spectrometric breakthrough essential for O ‐Glc NA c protein site assignments—a study of the O ‐Glc NA cylated protein H ost C ell F actor C 1 by Myers, Samuel A., Daou, Salima, Affar, El Bachir, Burlingame, Al

“…The development of electron‐based, unimolecular dissociation MS , i.e. electron capture and electron transfer dissociation ( ECD and ETD , respectively), has…”
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