Search Results - "Danzer, M."

Release and uptake of pathologic alpha-synuclein by Grozdanov, Veselin, Danzer, Karin M.

“…Parkinson’s disease (PD) is a chronic progressive neurodegenerative disease, which is characterized by severe loss of dopaminergic neurons and formation of…”
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TDP-43 is intercellularly transmitted across axon terminals by Feiler, Marisa S, Strobel, Benjamin, Freischmidt, Axel, Helferich, Anika M, Kappel, Julia, Brewer, Bryson M, Li, Deyu, Thal, Dietmar R, Walther, Paul, Ludolph, Albert C, Danzer, Karin M, Weishaupt, Jochen H

“…Transactive response DNA-binding protein 43 kD (TDP-43) is an aggregation-prone prion-like domain-containing protein and component of pathological…”
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Systematic comparison of the effects of Alpha-synuclein mutations on its oligomerization and aggregation by Lázaro, Diana F., Rodrigues, Eva F., Langohr, Ramona, Shahpasandzadeh, Hedieh, Ribeiro, Thales, Guerreiro, Patrícia, Gerhardt, Ellen, Kröhnert, Katharina, Klucken, Jochen, Pereira, Marcos D., Popova, Blagovesta, Kruse, Niels, Mollenhauer, Brit, Rizzoli, Silvio O., Braus, Gerhard H., Danzer, Karin M., Outeiro, Tiago

“…Copyright: © 2014 Lázaro et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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Exosomal cell-to-cell transmission of alpha synuclein oligomers by Danzer, Karin M, Kranich, Lisa R, Ruf, Wolfgang P, Cagsal-Getkin, Ozge, Winslow, Ashley R, Zhu, Liya, Vanderburg, Charles R, McLean, Pamela J

“…Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy…”
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The long-run consequences of Chernobyl: Evidence on subjective well-being, mental health and welfare by Danzer, Alexander M., Danzer, Natalia

“…This paper assesses the long-run toll taken by a large-scale technological disaster on welfare, well-being and mental health. We estimate the causal effect of…”
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Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients by Grozdanov, Veselin, Bliederhaeuser, Corinna, Ruf, Wolfgang P., Roth, Valerie, Fundel-Clemens, Kathrin, Zondler, Lisa, Brenner, David, Martin-Villalba, Ana, Hengerer, Bastian, Kassubek, Jan, Ludolph, Albert C., Weishaupt, Jochen H., Danzer, Karin M.

“…Despite extensive effort on studying inflammatory processes in the CNS of Parkinson’s disease (PD) patients, implications of peripheral monocytes are still…”
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Stress induced TDP-43 mobility loss independent of stress granules by Streit, Lisa, Kuhn, Timo, Vomhof, Thomas, Bopp, Verena, Ludolph, Albert C., Weishaupt, Jochen H., Gebhardt, J. Christof M., Michaelis, Jens, Danzer, Karin M.

“…TAR DNA binding protein 43 (TDP-43) is closely related to the pathogenesis of amyotrophic lateral sclerosis (ALS) and translocates to stress granules (SGs)…”
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Proteasome impairment by α-synuclein by Zondler, Lisa, Kostka, Marcus, Garidel, Patrick, Heinzelmann, Udo, Hengerer, Bastian, Mayer, Benjamin, Weishaupt, Jochen H, Gillardon, Frank, Danzer, Karin M

“…Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide and characterized by the loss of dopaminergic neurons in the…”
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The impact of photobiomodulation on the chondrogenic potential of adipose-derived stromal/stem cells by Schneider, C., Dungel, P., Priglinger, E., Danzer, M., Schädl, B., Nürnberger, S.

“…Due to their capacity to differentiate into the chondrogenic lineage, adipose-derived stromal/stem cells (ASC) are a promising source of therapeutically…”
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T-cell dysregulation is associated with disease severity in Parkinson's Disease by Bhatia, Divisha, Grozdanov, Veselin, Ruf, Wolfgang P, Kassubek, Jan, Ludolph, Albert C, Weishaupt, Jochen H, Danzer, Karin M

“…The dysregulation of peripheral immunity in Parkinson's Disease (PD) includes changes in both the relative numbers and gene expression of T cells. The presence…”
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Peripheral monocytes are functionally altered and invade the CNS in ALS patients by Zondler, Lisa, Müller, Kathrin, Khalaji, Samira, Bliederhäuser, Corinna, Ruf, Wolfgang P., Grozdanov, Veselin, Thiemann, Meinolf, Fundel-Clemes, Katrin, Freischmidt, Axel, Holzmann, Karlheinz, Strobel, Benjamin, Weydt, Patrick, Witting, Anke, Thal, Dietmar R., Helferich, Anika M., Hengerer, Bastian, Gottschalk, Kay-Eberhard, Hill, Oliver, Kluge, Michael, Ludolph, Albert C., Danzer, Karin M., Weishaupt, Jochen H.

“…Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease affecting primarily the upper and lower motor neurons. A common…”
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The Role of Lipids in the Initiation of α-Synuclein Misfolding by Kiechle, Martin, Grozdanov, Veselin, Danzer, Karin M.

“…The aggregation of α-synuclein (α-syn) is inseparably connected to Parkinson’s disease (PD). It is now well-established that certain forms of α-syn aggregates,…”
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Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice by Brenner, David, Sieverding, Kirsten, Bruno, Clara, Lüningschrör, Patrick, Buck, Eva, Mungwa, Simon, Fischer, Lena, Brockmann, Sarah J, Ulmer, Johannes, Bliederhäuser, Corinna, Philibert, Clémentine E, Satoh, Takashi, Akira, Shizuo, Boillée, Séverine, Mayer, Benjamin, Sendtner, Michael, Ludolph, Albert C, Danzer, Karin M, Lobsiger, Christian S, Freischmidt, Axel, Weishaupt, Jochen H

“…Heterozygous loss-of-function mutations of ( cause familial ALS, yet downstream mechanisms of mutations remained elusive. TBK1 is a pleiotropic kinase involved…”
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Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients by Yazar, Volkan, Kühlwein, Julia K., Knehr, Antje, Grozdanov, Veselin, Ekici, Arif B., Ludolph, Albert C., Danzer, Karin M.

“…Epigenetic remodeling is emerging as a critical process for several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Genetics alone…”
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Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease by Ruf, Wolfgang P., Palmer, Annette, Dörfer, Lena, Wiesner, Diana, Buck, Eva, Grozdanov, Veselin, Kassubek, Jan, Dimou, Leda, Ludolph, Albert C., Huber-Lang, Markus, Danzer, Karin M.

“…Systemic and neuroinflammatory processes play key roles in neurodegenerative diseases such as Parkinson's disease (PD). Physical trauma which induces…”
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Intracellular Alpha-Synuclein and Immune Cell Function by Grozdanov, Veselin, Danzer, Karin M

“…Intracellular alpha-synuclein has numerous effects on different functions of the cell. Although it is expressed in a wide spectrum of cell types from different…”
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Low T-cell reactivity to TDP-43 peptides in ALS by Ramachandran, Swetha, Grozdanov, Veselin, Leins, Bianca, Kandler, Katharina, Witzel, Simon, Mulaw, Medhanie, Ludolph, Albert C, Weishaupt, Jochen H, Danzer, Karin M

“…Dysregulation of the immune system in amyotrophic lateral sclerosis (ALS) includes changes in T-cells composition and infiltration of T cells in the brain and…”
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Personal, financial and time burden in inherited ichthyoses: A survey of 144 patients in a university-based setting by Klein, C, Oji, V, Sommer, R, Augustin, M, Ständer, S, Salzmann, S, Kiekbusch, K, Bodes, J, Danzer, M F, Traupe, H, Fischer, J, Steinke, S, Süßmuth, K

“…Patients with inherited ichthyosis suffer from scaling due to mutations affecting the epidermal barrier. Symptomatic treatment with ointments, bathing and…”
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PGC-1  is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis by Eschbach, J., Schwalenstocker, B., Soyal, S. M., Bayer, H., Wiesner, D., Akimoto, C., Nilsson, A.-C., Birve, A., Meyer, T., Dupuis, L., Danzer, K. M., Andersen, P. M., Witting, A., Ludolph, A. C., Patsch, W., Weydt, P.

“…Amyotrophic lateral sclerosis (ALS) is a devastating, adult-onset neurodegenerative disorder of the upper and lower motor systems. It leads to paresis, muscle…”
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Mitochondrial genome study in blood of maternally inherited ALS cases by Brockmann, Sarah J, Buck, Eva, Casoli, Tiziana, Meirelles, João L, Ruf, Wolfgang P, Fabbietti, Paolo, Holzmann, Karlheinz, Weishaupt, Jochen H, Ludolph, Albert C, Conti, Fiorenzo, Danzer, Karin M

“…ALS is a heterogeneous disease in which different factors such as mitochondrial phenotypes act in combination with a genetic predisposition. This study…”
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