Search Results - "Dantzer, F."

Expanding functions of ADP-ribosylation in the maintenance of genome integrity by Martin-Hernandez, K., Rodriguez-Vargas, J-M., Schreiber, V., Dantzer, F.

“…Cell response to genotoxic stress requires a complex network of sensors and effectors from numerous signaling and repair pathways, among them the nuclear…”
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Therapeutic considerations of PARP in stem cell biology: Relevance in cancer and beyond by Zeniou, M., Nguekeu-Zebaze, L., Dantzer, F.

“…[Display omitted] Cancer stem cells (CSCs) are of fundamental importance in tumor progression because of their tumor-initiating properties, their resistance to…”
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PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors by Farrés, J, Llacuna, L, Martin-Caballero, J, Martínez, C, Lozano, J J, Ampurdanés, C, López-Contreras, A J, Florensa, L, Navarro, J, Ottina, E, Dantzer, F, Schreiber, V, Villunger, A, Fernández-Capetillo, O, Yélamos, J

“…Erythropoiesis is a tightly regulated process in which multipotential hematopoietic stem cells produce mature red blood cells. Here we show that deletion of…”
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Poly(ADP-ribose)-dependent regulation of Snail1 protein stability by Rodríguez, M I, González-Flores, A, Dantzer, F, Collard, J, de Herreros, A G, Oliver, F J

“…Snail1 is a master regulator of the epithelial–mesenchymal transition (EMT) and has been implicated in key tumor biological processes such as invasion and…”
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A PARP1-ERK2 synergism is required for the induction of LTP by Visochek, L., Grigoryan, G., Kalal, A., Milshtein-Parush, H., Gazit, N., Slutsky, I., Yeheskel, A., Shainberg, A., Castiel, A., Seger, R., Langelier, M. F., Dantzer, F., Pascal, J. M., Segal, M., Cohen-Armon, M.

“…Unexpectedly, a post-translational modification of DNA-binding proteins, initiating the cell response to single-strand DNA damage, was also required for…”
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Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice by Nicolás, L, Martínez, C, Baró, C, Rodríguez, M, Baroja-Mazo, A, Sole, F, Flores, J M, Ampurdanés, C, Dantzer, F, Martin-Caballero, J, Aparicio, P, Yelamos, J

“…Poly(ADP-ribose) polymerase-2 (Parp-2) belongs to a family of enzymes that catalyse poly(ADP-ribosyl)ation of proteins. Parp-2 deficiency in mice (Parp-2 −/− )…”
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Functional Interaction between Poly(ADP-Ribose) Polymerase 2 (PARP-2) and TRF2: PARP Activity Negatively Regulates TRF2 by Dantzer, Françoise, Giraud-Panis, Marie-Josèphe, Jaco, Isabel, Amé, Jean-Christophe, Schultz, Inès, Blasco, Maria, Koering, Catherine-Elaine, Gilson, Eric, Ménissier-de Murcia, Josiane, de Murcia, Gilbert, Schreiber, Valérie

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo by Dantzer, Françoise, Luna, Luisa, Bjørås, Magnar, Seeberg, Erling

“…OGG1 is the major DNA glycosylase in human cells for removal of 7,8 dihydro-8-oxoguanine (8-oxoG), one of the most frequent endogenous base lesions formed in…”
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Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) activity in PARP-1 silenced tumour cells increases chemosensitivity to temozolomide and to a N3-adenine selective methylating agent by Tentori, L, Muzi, A, Dorio, A S, Scarsella, M, Leonetti, C, Shah, G M, Xu, W, Camaioni, E, Gold, B, Pellicciari, R, Dantzer, F, Zhang, J, Graziani, G

“…We recently demonstrated that poly(ADP-ribose) polymerase (PARP)-1 is involved in angiogenesis and tumour aggressiveness. In this study we have compared the…”
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A Fast Signal-Induced Activation of Poly(ADP-Ribose) Polymerase: A Novel Downstream Target of Phospholipase C by Homburg, S., Visochek, L., Moran, N., Dantzer, F., Priel, E., Asculai, E., Schwartz, D., Rotter, V., Dekel, N., Cohen-Armon, M.

“…We present the first evidence for a fast activation of the nuclear protein poly(ADP-ribose) polymerase (PARP) by signals evoked in the cell membrane,…”
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ADP‐ribosyltransferases, an update on function and nomenclature by Lüscher, Bernhard, Ahel, Ivan, Altmeyer, Matthias, Ashworth, Alan, Bai, Peter, Chang, Paul, Cohen, Michael, Corda, Daniela, Dantzer, Françoise, Daugherty, Matthew D., Dawson, Ted M., Dawson, Valina L., Deindl, Sebastian, Fehr, Anthony R., Feijs, Karla L. H., Filippov, Dmitri V., Gagné, Jean‐Philippe, Grimaldi, Giovanna, Guettler, Sebastian, Hoch, Nicolas C., Hottiger, Michael O., Korn, Patricia, Kraus, W. Lee, Ladurner, Andreas, Lehtiö, Lari, Leung, Anthony K. L., Lord, Christopher J., Mangerich, Aswin, Matic, Ivan, Matthews, Jason, Moldovan, George‐Lucian, Moss, Joel, Natoli, Gioacchino, Nielsen, Michael L., Niepel, Mario, Nolte, Friedrich, Pascal, John, Paschal, Bryce M., Pawłowski, Krzysztof, Poirier, Guy G., Smith, Susan, Timinszky, Gyula, Wang, Zhao‐Qi, Yélamos, José, Yu, Xiaochun, Zaja, Roko, Ziegler, Mathias

“…ADP‐ribosylation, a modification of proteins, nucleic acids, and metabolites, confers broad functions, including roles in stress responses elicited, for…”
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Poly(ADP-ribose): novel functions for an old molecule by Schreiber, Valérie, Dantzer, Françoise, Ame, Jean-Christophe, de Murcia, Gilbert

“…The addition to proteins of the negatively charged polymer of ADP-ribose (PAR), which is synthesized by PAR polymerases (PARPs) from NAD(+), is a unique…”
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Distinct roles for PARP-1 and PARP-2 in c-Myc–driven B-cell lymphoma in mice by Galindo-Campos, Miguel A., Lutfi, Nura, Bonnin, Sarah, Martínez, Carlos, Velasco-Hernandez, Talia, García-Hernández, Violeta, Martín-Caballero, Juan, Ampurdanés, Coral, Gimeno, Ramón, Colomo, Lluis, Roué, Gaël, Guilbaud, Guillaume, Dantzer, Françoise, Navarro, Pilar, Murga, Matilde, Fernández-Capetillo, Oscar, Bigas, Anna, Menéndez, Pablo, Sale, Julian E., Yélamos, José

“…Dysregulation of the c-Myc oncogene occurs in a wide variety of hematologic malignancies, and its overexpression has been linked with aggressive tumor…”
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Large scale and heavy traffic asymptotics for systems with unreliable servers by DANTZER, J.-F, MITRANI, I, ROBERT, Ph

“…The asymptotic behaviour of the M/M/n queue, with servers subject to independent breakdowns and repairs, is examined in the limit where the number of servers…”
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A Fast Signal–Induced Activation of Poly(Adp-Ribose) Polymerase by Homburg, S., Visochek, L., Moran, N., Dantzer, F., Priel, E., Asculai, E., Schwartz, D., Rotter, V., Dekel, N., Cohen-Armon, M.

“…We present the first evidence for a fast activation of the nuclear protein poly(ADP-ribose) polymerase (PARP) by signals evoked in the cell membrane,…”
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Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse by de Murcia, Gilbert, Ménissier de Murcia, Josiane, Ricoul, Michelle, Tartier, Laurence, Niedergang, Claude, Huber, Aline, Dantzer, Françoise, Schreiber, Valérie, Amé, Jean-Christophe, Dierich, Andrée, LeMeur, Marianne, Sabatier, Laure, Chambon, Pierre

“…The DNA damage‐dependent poly(ADP‐ribose) polymerases, PARP‐1 and PARP‐2, homo‐ and heterodimerize and are both involved in the base excision repair (BER)…”
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Characterization of a Gain-of-Function Mutant of Poly(ADP-Ribose) Polymerase by Miranda, E.A., Dantzer, F., Ofarrell, M., Demurcia, G., Demurcia, J.M.

“…In order to examine the stucture-function relationship of the poly (ADP-ribose) polymerase (PARP) catalytic domain, potential active-site residues in the…”
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Control of AIF-mediated Cell Death by the Functional Interplay of SIRT1 and PARP-1 in Response to DNA Damage by Kolthur-Seetharam, Ullas, Dantzer, Françoise, McBurney, Michael W., Murcia1, Gilbert de, Sassone-Corsi, Paolo

“…Cell survival after genotoxic stress is determined by a counterbalance of pro- and anti-death factors. Sirtuins (SIRTs) are deacetylases that promote cell…”
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Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA by Seeberg, E, Luna, L, Morland, I, Eide, L, Johnsen, B, Larsen, E, Alseth, I, Dantzer, F, Baynton, K, Aamodt, R, Kristiansen, K I, Rognes, T, Klungland, A, Bjørås, M

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Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair by Dantzer, Françoise, Amé, Jean-Christophe, Schreiber, Valérie, Nakamura, Jun, Ménissier-de Murcia, Josiane, de Murcia, Gilbert

“…Changes in chromatin structure emanating from DNA breaks are among the most initiating events in the damage response of the cell. In higher eukaryotes,…”
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