Search Results - "Dantas, Ezequiel"
-
1
Extracellular Acidosis and mTOR Inhibition Drive the Differentiation of Human Monocyte-Derived Dendritic Cells
Published in Cell reports (Cambridge) (05-05-2020)“…During inflammation, recruited monocytes can differentiate either into macrophages or dendritic cells (DCs); however, little is known about the environmental…”
Get full text
Journal Article -
2
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer
Published in Nature communications (08-08-2022)“…Cancer cachexia is a common, debilitating condition with limited therapeutic options. Using an established mouse model of lung cancer, we find that cachexia is…”
Get full text
Journal Article -
3
Strategic Assessment of Lisbon’s Accessibility and Mobility Problems from an Equity Perspective
Published in Networks and spatial economics (01-06-2018)“…Accessibility planning with reference to sustainability and equity principles has been advocated as the best approach to deal with the urban mobility…”
Get full text
Journal Article -
4
Correction to: Strategic Assessment of Lisbon’s Accessibility and Mobility Problems from an Equity Perspective
Published in Networks and spatial economics (01-09-2021)“…A Correction to this paper has been published: https://doi.org/10.1007/s11067-021-09544-7…”
Get full text
Journal Article -
5
TIMP1 is an early biomarker for detection and prognosis of lung cancer
Published in Clinical and translational medicine (01-10-2023)“…Lung cancer remains the major cause of cancer-related deaths worldwide. Early stages of lung cancer are characterized by long asymptomatic periods that are…”
Get full text
Journal Article -
6
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase
Published in Cancer & metabolism (24-03-2021)“…Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that…”
Get full text
Journal Article -
7
Unravelling the Interplay between Extracellular Acidosis and Immune Cells
Published in Mediators of inflammation (01-01-2018)“…The development of an acidic tissue environment is a hallmark of a variety of inflammatory processes and solid tumors. However, little attention has been paid…”
Get full text
Journal Article -
8
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
Published in Nature communications (11-06-2024)“…Spaceflight induces an immune response in astronauts. To better characterize this effect, we generated single-cell, multi-ome, cell-free RNA (cfRNA),…”
Get full text
Journal Article -
9
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer
Published in Acta Physiologica (01-08-2024)“…Aim To investigate systemic regulators of the cancer‐associated cachexia syndrome (CACS) in a pre‐clinical model for lung cancer with the goal to identify…”
Get full text
Journal Article -
10
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Published in Nature (London) (29-08-2024)“…Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming…”
Get full text
Journal Article -
11
Histidine-Rich Glycoprotein Inhibits HIV-1 Infection in a pH-Dependent Manner
Published in Journal of virology (15-02-2019)“…Histidine-rich glycoprotein (HRG) is an abundant plasma protein with a multidomain structure, allowing its interaction with many ligands, including…”
Get full text
Journal Article -
12
Fever-range hyperthermia improves the anti-apoptotic effect induced by low pH on human neutrophils promoting a proangiogenic profile
Published in Cell death & disease (27-10-2016)“…Neutrophils have the shortest lifespan among leukocytes and usually die via apoptosis, limiting their deleterious potential. However, this tightly regulated…”
Get full text
Journal Article -
13
Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells
Published in Oncotarget (08-11-2016)“…Local acidosis is a common feature of allergic, vascular, autoimmune, and cancer diseases. However, few studies have addressed the effect of extracellular pH…”
Get full text
Journal Article -
14
-
15
Dosaje de una glicoproteína rica en histidina en el lavado broncoalveolar de pacientes con enfermedades intersticiales difusas de pulmón
Published in Revista americana de medicina respiratoria (01-06-2015)“…Introducción: La proteína rica en histidina (HRG) se encuentra en el plasma en altas concentraciones (100-150 μg/ml) y puede interaccionar con una gran…”
Get full text
Journal Article -
16
A big data approach for smart transportation management on bus network
Published in 2016 IEEE International Smart Cities Conference (ISC2) (01-09-2016)“…Urbanization in developing countries has resulted in increased demand for public transportation in the face of limited resources. This requires smart…”
Get full text
Conference Proceeding -
17
SMARTBIKE: Policy making and decision support for bike share systems
Published in 2016 IEEE International Smart Cities Conference (ISC2) (01-09-2016)“…Bike share systems have been implemented in many cities to provide an alternative low-cost environmentally friendly and healthy public transportation. Citizens…”
Get full text
Conference Proceeding