Search Results - "Dansin, E."
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Lung cancer patients with HER2 mutations treated with chemotherapy and HER2-targeted drugs: results from the European EUHER2 cohort
Published in Annals of oncology (01-02-2016)“…HER2 mutations have been identified as oncogenic drivers in lung cancers and are found in 1–2% of lung adenocarcinomas. There is, to date, no standard of care…”
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The future: surgical advances in MEN1 therapeutic approaches and management strategies
Published in Endocrine-related cancer (01-10-2017)“…Multiple endocrine neoplasia type 1 (MEN1) is a hereditary autosomal dominant disorder associated with numerous neuroendocrine tumors (NETs). Recent advances…”
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Méthodes diagnostiques et stratégie thérapeutique des TNE pulmonaires (tumeurs carcinoïdes typiques et atypiques)
Published in Oncologie (Paris, France) (2020)“…Les carcinoïdes bronchiques typiques ou atypiques sont des tumeurs rares. La prise en charge des formes localisées repose essentiellement sur la chirurgie, et…”
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Clinical characteristics and outcomes of non-small cell lung cancer (NSCLC) patients harboring MET exon 14 splice sites mutations
Published in Annals of oncology (01-10-2018)Get full text
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Clinical characteristic and survival outcomes of patients with advanced NSCLC according to KRAS mutational status in the French real-life ESME cohort
Published in ESMO open (01-06-2024)“…The RAS/MEK signaling pathway is essential in carcinogenesis and frequently altered in non-small-cell lung cancer (NSCLC), notably by KRAS mutations (KRASm)…”
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MET exon 14 splicing sites mutations: A new therapeutic opportunity in lung cancer
Published in Revue des maladies respiratoires (01-10-2018)“…The mutations leading to MET exon 14 skipping represent a new class of molecular alterations described in various cancers. These alterations are observed in 2…”
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Necrosis- and apoptosis-related Met cleavages have divergent functional consequences
Published in Cell death & disease (01-05-2015)“…Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of…”
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Cost-effectiveness of three strategies for second-line erlotinib initiation in nonsmall-cell lung cancer: the ERMETIC study part 3
Published in The European respiratory journal (01-01-2012)“…Several clinical and biological parameters are known to influence the efficacy of second-line erlotinib therapy for nonsmall cell lung cancer (NSCLC), but…”
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Phase I dose-escalation study of oral vinflunine in combination with erlotinib in pre-treated and unselected EGFR patients with locally advanced or metastatic non-small-cell lung cancer
Published in Cancer chemotherapy and pharmacology (01-02-2014)“…Background Erlotinib, the epidermal growth factor receptor tyrosine kinase inhibitor, and the intra-venous vinflunine vinca alkaloid microtubule inhibitor have…”
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Megestrol acetate versus metronomic cyclophosphamide in patients having exhausted all effective therapies under standard care
Published in British journal of cancer (13-04-2010)“…Background: To evaluate the antitumour activity and safety of metronomic cyclophosphamide vs megestrol acetate in progressive and advanced cancer patients…”
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Somatic profile in lung cancers is associated to reproductive factors in never-smokers women: Results from the IFCT-1002 BioCAST study
Published in Respiratory medicine and research (01-03-2020)“…Lung cancer in women is on the rise, with a higher proportion occurring in lifelong never-smokers. Lung cancer in never-smokers (LCINS) exhibits a high…”
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Reflections on the limits of specific treatments in thoracic oncology
Published in Revue des maladies respiratoires (01-02-2015)“…The modest impact of specific treatments is a major problem in oncology and particularly for metastatic lung cancer patients. Therapeutic progress achieved by…”
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Inter- and intraobserver consistency in assessing eligibility for bevacizumab (BVZ) in non-small-cell lung cancer (NSCLC) patients with centrally located tumors
Published in Annals of oncology (01-08-2010)“…Bevacizumab (BVZ) combined with platinum-based therapy is registered for first-line treatment of nonsquamous non-small-cell lung cancer (NSCLC). Patients with…”
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Anti-Hu antibody syndrome: diagnostic and therapeutic difficulties
Published in Revue des maladies respiratoires (01-09-2013)“…Anti-Hu antibody syndrome is a paraneoplastic syndrome usually associated with small cell lung carcinoma which induces various symptoms, particularly…”
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Durable responses to Erlotinib despite KRAS mutations in two patients with metastatic lung adenocarcinoma
Published in Annals of oncology (01-06-2010)Get full text
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Information on head, neck and lung cancers
Published in Bulletin du cancer (2009)“…Notable advances have been achieved in head and neck cancer and in lung cancer as regards oncogenesis knowledge and treatment optimization. Multimodal…”
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