Search Results - "Danser, AHJ"

A human trigeminovascular biomarker for antimigraine drugs: A randomised, double-blind, placebo-controlled, crossover trial with sumatriptan by Ibrahimi, K, Danser, Ahj, Terwindt, G M, van den Meiracker, A H, MaassenVanDenBrink, A

“…Current antimigraine drugs are believed, besides their direct vasoconstrictive effect, to inhibit calcitonin gene-related peptide (CGRP) release from…”
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Local renin–angiotensin systems: the unanswered questions by Jan Danser, A.H.

“…The concept of local renin–angiotensin systems has been introduced almost 20 years ago to explain the beneficial blood pressure-independent effects of ACE…”
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A human capsaicin model to quantitatively assess salivary CGRP secretion by van Oosterhout, W P J, Schoonman, G G, Garrelds, I M, Danser, A H J, Chan, K Y, Terwindt, G M, Ferrari, M D, MaassenVanDenBrink, A

“…Capsaicin induces the release of calcitonin gene-related peptide (CGRP) via the transient receptor potential channel V1 (TRPV1). The CGRP response after…”
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Influence of varying estrogen levels on trigeminal CGRP release in healthy women by Ibrahimi, K, Danser, AHJ, Villalón, CM, van den Meiracker, AH, MaassenVanDenBrink, A

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PO6_05. Restoring the angiogenic imbalance in preeclampsia and fetal growth restriction: is sflt-1 removal sufficient? by Kluivers, ACM, Biesbroek, A., Visser, W., Saleh, L., Russcher, H., Danser, AHJ, Neuman, RI

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Renin, Prorenin and the Putative (Pro)renin Receptor by Jan Danser, A H, Deinum, Jaap

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Trigeminovascular calcitonin gene-related peptide function in Cacna1a R192Q-mutated knock-in mice by Chan, Kayi Y, Labastida-Ramírez, Alejandro, Ramírez-Rosas, Martha B, Labruijere, Sieneke, Garrelds, Ingrid M, Danser, Alexander HJ, van den Maagdenberg, Arn MJM, MaassenVanDenBrink, Antoinette

“…Familial hemiplegic migraine type 1 (FHM1) is a rare migraine subtype. Whereas transgenic knock-in mice with the human pathogenic FHM1 R192Q missense mutation…”
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Therapeutic Potential of Sunitinib in Ameliorating Endothelial Dysfunction in Type 2 Diabetic Rats by Mahdi, Ali, Jiao, Tong, Tratsiakovich, Yahor, Wernly, Bernhard, Yang, Jiangning, Östenson, Claes-Göran, Danser, A H Jan, Pernow, John, Zhou, Zhichao

“…Sunitinib, a multi-targeted tyrosine kinase receptor inhibitor used to treat renal-cell carcinoma and gastrointestinal stromal tumor, was recently shown to…”
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Aliskiren, a Human Renin Inhibitor, Ameliorates Cardiac and Renal Damage in Double-Transgenic Rats by Pilz, Bernhard, Shagdarsuren, Erdenechimeg, Wellner, Maren, Fiebeler, Anette, Dechend, Ralf, Gratze, Petra, Meiners, Silke, Feldman, David L, Webb, Randy L, Garrelds, Ingrid M, Danser, A H. Jan, Luft, Friedrich C, Müller, Dominik N

“…We tested the hypothesis that the renin inhibitor aliskiren ameliorates organ damage in rats transgenic for human renin and angiotensinogen genes (double…”
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Elevated Blood Pressure and Heart Rate in Human Renin Receptor Transgenic Rats by Burcklé, Céline A, Danser, A H. Jan, Müller, Dominik N, Garrelds, Ingrid M, Gasc, Jean-Marie, Popova, Elena, Plehm, Ralph, Peters, Jörg, Bader, Michael, Nguyen, Geneviève

“…Recently, a receptor for renin was described that may be important for vascular uptake and activation of (pro)renin, thus leading to local generation of…”
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Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness by KLOTZ, Stefan, FORONJY, Robert F, DICKSTEIN, Marc L, ANGUO GU, GARRELDS, Ingrid M, JAN DANSER, A. H, OZ, Mehmet C, D'ARMIENTO, Jeanine, BURKHOFF, Daniel

“…Left ventricular assist devices (LVADs) induce reverse remodeling of the failing heart except for the extracellular matrix, which exhibits additional…”
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Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement by Zhou, Zhichao, Sorop, Oana, de Beer, Vincent J., Heinonen, Ilkka, Cheng, Caroline, Jan Danser, A. H., Duncker, Dirk J., Merkus, Daphne

“…We previously demonstrated that uridine adenosine tetraphosphate (Up 4 A) induces potent and partially endothelium-dependent relaxation in the healthy porcine…”
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FUNCTIONAL CONSEQUENCES OF PRORENIN AND RENIN BINDING IN VASCULAR SMOOTH MUSCLE CELLS EXPRESSING THE (PRO)RENIN RECEPTOR: ROLE OF ANGIOTENSIN II: PP.13.473 by Batenburg, W, Leijten, F, Müller, DN, Danser, AHJ

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ACE SPLICE-SITE MUTATION RESULTING IN 5–10-FOLD ELEVATED ACE LEVELS ALTERS NEITHER BASELINE RENIN AND ANGIOTENSIN LEVELS NOR THE RESPONSE TO ACE INHIBITION: PP.24.464 by Persu, A, Lambert, M, Gala, JL, Danser, AHJ

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DAILY RED WINE CONSUMPTION IMPROVES VASCULAR FUNCTION IN YOUNG HEALTHY WOMEN, PROPABLY BY AN ENDOTHELIUM-DEPENDENT NITRIC OXIDE-SOLUBLE GUANYLYL CYCLASE - MEDIATED PATHWAY: PP.6.236 by Botden, I, Langendonk, JG, Danser, AHJ, Sijbrands, EJG

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Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries by BATENBURG, Wendy W, GARRELDS, Ingrid M, BERNASCONI, Catherine Chapuis, JUILLERAT-JEANNERET, Lucienne, VAN KATS, Jorge P, SAXENA, Pramod R, DANSER, A. H

“…Angiotensin (Ang) II type 2 (AT2) receptor stimulation results in coronary vasodilation in the rat heart. In contrast, AT2 receptor-mediated vasodilation could…”
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Development of an experimental model to study trigeminal nerve-mediated vasodilation on the human forehead by Ibrahimi, K, Vermeersch, S, Danser, Ahj, Villalón, C M, van den Meiracker, A H, de Hoon, J, MaassenVanDenBrink, A

“…During migraine, trigeminal sensory nerve terminals release calcitonin gene-related peptide (CGRP), inducing nociception and vasodilation. Applied on the skin,…”
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Bradykinin, angiotensin-(1–7), and ACE inhibitors: how do they interact? by Tom, Beril, Dendorfer, Andreas, Jan Danser, A.H

“…The beneficial effect of ACE inhibitors in hypertension and heart failure may relate, at least in part, to their capacity to interfere with bradykinin…”
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The role of calcitonin gene-related peptide (CGRP) in ischemic preconditioning in isolated rat hearts by Chai, Wenxia, Mehrotra, Suneet, Jan Danser, A.H., Schoemaker, Regien G.

“…Brief coronary artery occlusion can protect the heart against damage during subsequent prolonged coronary artery occlusion; ischemic preconditioning. The role…”
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Angiotensin II and the Heart: On the Intracrine Renin-Angiotensin System by De Mello, Walmor C, Danser, A H. Jan

“…The active end product of the renin-angiotensin system, angiotensin II (Ang II), through the activation of specific Ang II receptors, regulates cardiac…”
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