Search Results - "Danpure, C.J."

Peroxisomal alanine:glyoxylate aminotransferase deficiency in primary hyperoxaluria type I by Danpure, C.J., Jennings, P.R

“…Activities of alanine:glyoxylate aminotransferase in the livers of two patients with primary hyperoxaluria type I were substantially lower than those found in…”
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Primary hyperoxaluria type 1 and peroxisome-to-mitochondrion mistargeting of alanine:glyoxylate aminotransferase by Danpure, C J

“…Under the influence of dietary selection pressure, the intracellular compartmentalization of alanine:glyoxylate aminotransferase (AGT) has changed on many…”
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A vertical (pseudodominant) pattern of inheritance in the autosomal recessive disease primary hyperoxaluria type 1: lack of relationship between genotype, enzymic phenotype, and disease severity by Hoppe, B, Danpure, C J, Rumsby, G, Fryer, P, Jennings, P R, Blau, N, Schubiger, G, Neuhaus, T, Leumann, E

“…Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disease caused by a deficiency of alanine:glyoxylate aminotransferase (encoded by the AGXT…”
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Enzymological and mutational analysis of a complex primary hyperoxaluria type I phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation by Danpure, C J, Purdue, P E, Fryer, P, Griffiths, S, Allsop, J, Lumb, MJ, Guttridge, K M, Jennings, PR, Davidson, N O

“…Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disease caused by a deficiency of the liver-specific peroxisomal enzyme alanine:glyoxylate…”
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Immunological heterogeneity of hepatic alanine:glyoxylate aminotransferase in primary hyperoxaluria type 1 by Wise, P.J., Danpure, C.J., Jennings, P.R.

“…Immunoblotting of human liver sonicates, after SDS-polyacrylamide gel electrophoresis, demonstrated the presence of a 40 kDa protein, corresponding to the…”
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Exclusion of primary hyperoxaluria type I (PHI) in end-stage renal failure by enzymatic analysis of a percutaneous hepatic biopsy by Morgan, S H, Danpure, C J, Bending, M R, Eisinger, A J

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Further studies on the effect of chloroquine on the uptake, metabolism and intracellular translocation of [35S]cystine in cystinotic fibroblasts by Danpure, C J, Jennings, P R, Fyfe, D A

“…The present study uses the lysosomotropic drug chloroquine to investigate the mechanisms by which exogenous [35S]cystine is able to label the intracellular…”
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Determination of gold in plasma and plasma fractions by atomic absorption spectrometry and by neutron activation analysis by Ward, R J, Danpure, C J, Fyfe, D A

“…Three techniques of gold analysis, flame and electrothermal atomic absorption spectrometry and neutron activation analysis, have been compared, using plasma…”
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Lysosomal uptake of actinide elements by Taylor, D M, Danpure, C J

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The Subcellular Distribution of Plutonium in Rat Liver by Boocock, G., Danpure, C. J., Popplewell, D. S., Taylor, D. M.

“…The subcellular distribution of plutonium and 59 Fe in rat liver has been studied over periods of up to 96 days following intravenous injection of one or both…”
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The Effect of Internally Deposited Plutonium-239 on the Lysosomes of Rat Liver by Danpure, Christopher J., Taylor, David M.

“…The effects of plutonium-239, an α-particle emitting radionuclide which deposits mainly in the lysosomes, on the activity of various lysosomal enzymes have…”
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