Search Results - "Dannenberg, Lisa"
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Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1
Published in Circulation research (14-02-2020)“…A reduced rate of myocardial infarction has been reported in patients with atrial fibrillation treated with FXa (factor Xa) inhibitors including rivaroxaban…”
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Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells
Published in Nature communications (14-12-2023)“…Red blood cells (RBC) are the major carriers of sphingosine-1-phosphate (S1P) in blood. Here we show that variations in RBC S1P content achieved by altering…”
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Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction
Published in Nature communications (26-04-2023)“…Antiplatelet medication is standard of care in acute myocardial infarction (AMI). However, it may have obscured beneficial properties of the activated platelet…”
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Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis
Published in Scientific reports (28-07-2022)“…Thromboembolism is frequent in infective endocarditis (IE). However, the optimal antithrombotic regimen in IE is unknown. Staphylococcus aureus (SA) is the…”
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5
Aortic valve calcification is subject to aortic stenosis severity and the underlying flow pattern
Published in Heart and vessels (01-02-2021)“…Sex- and flow-related aortic valve calcification (AVC) studies are still limited in number, and data on the exact calcium quantity and distribution are scarce…”
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Impact of high on-treatment platelet reactivity after angioplasty in patients with peripheral arterial disease
Published in Platelets (Edinburgh) (03-04-2021)“…Objective: High on-treatment platelet reactivity (HTPR) to dual antiplatelet therapy (DAPT) predicts adverse events in coronary artery disease patients. In…”
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The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data
Published in Annals of intensive care (03-05-2023)“…Background This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in the intensive care unit (ICU). Methods…”
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Rivaroxaban reduces thromboxane induced platelet aggregation - the forgotten compass arm?
Published in Platelets (Edinburgh) (17-11-2021)Get full text
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Predictors of calcification distribution in severe tricuspid aortic valve stenosis
Published in The International Journal of Cardiovascular Imaging (01-09-2021)“…We investigated aortic valve calcification (AVC) distribution and predictors for leaflet calcification patterns in patients with severe tricuspid aortic valve…”
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Mitochondrial Creatine Kinase 2 (Ckmt2) as a Plasma-Based Biomarker for Evaluating Reperfusion Injury in Acute Myocardial Infarction
Published in Biomedicines (16-10-2024)“…Acute myocardial infarction (AMI), characterized by irreversible heart muscle damage and impaired cardiac function caused by myocardial ischemia, is a leading…”
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SYSTEMI - systemic organ communication in STEMI: design and rationale of a cohort study of patients with ST-segment elevation myocardial infarction
Published in BMC cardiovascular disorders (03-05-2023)“…ST-segment elevation myocardial infarction (STEMI) still causes significant mortality and morbidity despite best-practice revascularization and adjunct medical…”
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Excess Mortality in Aspirin and Dipyrone (Metamizole) Co-Medicated in Patients With Cardiovascular Disease: A Nationwide Study
Published in Journal of the American Heart Association (16-11-2021)“…Background Pain is a major issue in our aging society. Dipyrone (metamizole) is one of the most frequently used analgesics. Additionally, it has been shown to…”
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Risk prediction of bleeding and MACCE by PRECISE-DAPT score post-PCI
Published in International journal of cardiology. Heart & vasculature (01-04-2021)“…Guidelines recommend the PRECISE-DAPT (PD) score to adapt duration of dual antiplatelet therapy due to bleeding risk. However, there is first evidence that PD…”
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Sphingosine‐1‐phosphate improves outcome of no‐reflow acute myocardial infarction via sphingosine‐1‐phosphate receptor 1
Published in ESC Heart Failure (01-02-2023)“…Aims Therapeutic options targeting post‐ischaemic cardiac remodelling are sparse. The bioactive sphingolipid sphingosine‐1‐phosphate (S1P) reduces…”
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Pannexin-1 Deficient Mice Have an Increased Susceptibility for Atrial Fibrillation and Show a QT-Prolongation Phenotype
Published in Cellular physiology and biochemistry (01-01-2016)“…Background/Aims: Pannexin-1 (Panx1) is an ATP release channel that is ubiquitously expressed and coupled to several ligand-gated receptors. In isolated cardiac…”
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Dynamic coronary roadmapping during percutaneous coronary intervention: a feasibility study
Published in European journal of medical research (31-07-2018)“…A novel software ("Dynamic Coronary Roadmap") was developed, which offers a real-time, dynamic overlay of the coronary tree on fluoroscopy. Once the roadmap…”
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Cardioprotection by very mild hypothermia in mice
Published in Cardiovascular diagnosis and therapy (01-02-2019)“…Target temperature management is recommended in post-resuscitation care. Additionally, hypothermia is a promising option in adjunctive therapy of acute…”
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Cellular mechanisms and recommended drug-based therapeutic options in diabetic cardiomyopathy
Published in Pharmacology & therapeutics (Oxford) (01-12-2021)“…Diabetes mellitus (DM) is associated with a specific cardiac phenotype characterized by structural and functional alterations. This so-called diabetic…”
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Targeting the human microbiome and its metabolite TMAO in cardiovascular prevention and therapy
Published in Pharmacology & therapeutics (Oxford) (01-09-2020)“…The human gut microbiota is the most important active part of the intestinal micro-ecosystem. Lifestyle modification, drug intake and nutrition have an impact…”
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Potent anti‐inflammatory properties of HDL in vascular smooth muscle cells mediated by HDL‐S1P and their impairment in coronary artery disease due to lower HDL‐S1P: a new aspect of HDL dysfunction and its therapy
Published in The FASEB journal (01-01-2019)“…ABSTRACT Dysfunctional HDL is associated with coronary artery disease (CAD), but its effect on inflammation in vascular smooth muscle cells (VSMCs) in…”
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