Search Results - "Danneels, Adeline"

A reporter cell line for the automated quantification of SARS-CoV-2 infection in living cells by Desmarets, Lowiese, Callens, Nathalie, Hoffmann, Eik, Danneels, Adeline, Lavie, Muriel, Couturier, Cyril, Dubuisson, Jean, Belouzard, Sandrine, Rouillé, Yves

“…The SARS-CoV-2 pandemic and the urgent need for massive antiviral testing highlighted the lack of a good cell-based assay that allowed for a fast, automated…”
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Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice by Belouzard, Sandrine, Machelart, Arnaud, Sencio, Valentin, Vausselin, Thibaut, Hoffmann, Eik, Deboosere, Nathalie, Rouillé, Yves, Desmarets, Lowiese, Séron, Karin, Danneels, Adeline, Robil, Cyril, Belloy, Loic, Moreau, Camille, Piveteau, Catherine, Biela, Alexandre, Vandeputte, Alexandre, Heumel, Séverine, Deruyter, Lucie, Dumont, Julie, Leroux, Florence, Engelmann, Ilka, Alidjinou, Enagnon Kazali, Hober, Didier, Brodin, Priscille, Beghyn, Terence, Trottein, François, Deprez, Benoit, Dubuisson, Jean

“…Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in…”
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IL-12Rβ2 is essential for the development of experimental cerebral malaria by Fauconnier, Mathilde, Palomo, Jennifer, Bourigault, Marie-Laure, Meme, Sandra, Szeremeta, Frédéric, Beloeil, Jean-Claude, Danneels, Adeline, Charron, Sabine, Rihet, Pascal, Ryffel, Bernhard, Quesniaux, Valérie F J

“…A Th1 response is required for the development of Plasmodium berghei ANKA (PbA)-induced experimental cerebral malaria (ECM). The role of pro-Th1 IL-12 in…”
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Regulation of core expression during the hepatitis C virus life cycle by Afzal, Muhammad Sohail, Alsaleh, Khaled, Farhat, Rayan, Belouzard, Sandrine, Danneels, Adeline, Descamps, Véronique, Duverlie, Gilles, Wychowski, Czeslaw, Zaidi, Najam Us Sahar Sadaf, Dubuisson, Jean, Rouillé, Yves

“…Core plays a critical role during hepatitis C virus (HCV) assembly, not only as a structural component of the virion, but also as a regulator of the formation…”
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Protein Kinase C-Theta Is Required for Development of Experimental Cerebral Malaria by Fauconnier, Mathilde, Bourigault, Marie-Laure, Meme, Sandra, Szeremeta, Frederic, Palomo, Jennifer, Danneels, Adeline, Charron, Sabine, Fick, Lizette, Jacobs, Muazzam, Beloeil, Jean-Claude, Ryffel, Bernhard, Quesniaux, Valerie F.J

“…Cerebral malaria is the most severe neurologic complication in children and young adults infected with Plasmodium falciparum . T-cell activation is required…”
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The C-terminal domain of the MERS coronavirus M protein contains a trans-Golgi network localization signal by Perrier, Anabelle, Bonnin, Ariane, Desmarets, Lowiese, Danneels, Adeline, Goffard, Anne, Rouillé, Yves, Dubuisson, Jean, Belouzard, Sandrine

“…Coronavirus M proteins represent the major protein component of the viral envelope. They play an essential role during viral assembly by interacting with all…”
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The KxGxYR and DxE motifs in the C-tail of the Middle East respiratory syndrome coronavirus membrane protein are crucial for infectious virus assembly by Desmarets, Lowiese, Danneels, Adeline, Burlaud-Gaillard, Julien, Blanchard, Emmanuelle, Dubuisson, Jean, Belouzard, Sandrine

“…The coronavirus’ (CoV) membrane (M) protein is the driving force during assembly, but this process remains poorly characterized. Previously, we described two…”
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MERS-CoV and SARS-CoV-2 membrane proteins are modified with polylactosamine chains by Juckel, Dylan, Desmarets, Lowiese, Danneels, Adeline, Rouillé, Yves, Dubuisson, Jean, Belouzard, Sandrine

“…Coronaviruses are positive-stranded RNA enveloped viruses. The helical nucleocapsid is surrounded by a lipid bilayer in which are anchored three viral…”
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Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin by Millet, Jean K., Séron, Karin, Labitt, Rachael N., Danneels, Adeline, Palmer, Kenneth E., Whittaker, Gary R., Dubuisson, Jean, Belouzard, Sandrine

“…Highly pathogenic human coronaviruses associated with a severe respiratory syndrome, including Middle East respiratory syndrome coronavirus (MERS-CoV), have…”
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Entry and Release of Hepatitis C Virus in Polarized Human Hepatocytes by Belouzard, Sandrine, Danneels, Adeline, Fénéant, Lucie, Séron, Karin, Rouillé, Yves, Dubuisson, Jean

“…Hepatitis C virus (HCV) primarily infects hepatocytes, which are highly polarized cells. The relevance of cell polarity in the HCV life cycle has been…”
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HCoV-229E spike protein fusion activation by trypsin-like serine proteases is mediated by proteolytic processing in the S2' region by Bonnin, Ariane, Danneels, Adeline, Dubuisson, Jean, Goffard, Anne, Belouzard, Sandrine

“…Human coronavirus 229E (HCoV-229E) is responsible for common colds. Like other coronaviruses, HCoV-229E exploits cellular proteases to activate fusion mediated…”
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Correction for Belouzard et al., "Entry and Release of Hepatitis C Virus in Polarized Human Hepatocytes" by Belouzard, Sandrine, Danneels, Adeline, Fénéant, Lucie, Séron, Karin, Rouillé, Yves, Dubuisson, Jean

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Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice by Belouzard, Sandrine, Machelart, Arnaud, Sencio, Valentin, Vausselin, Thibaut, Hoffmann, Eik, Deboosere, Nathalie, Rouillé, Yves, Desmarets, Lowiese, Séron, Karin, Danneels, Adeline, Robil, Cyril, Belloy, Loic, Moreau, Camille, Piveteau, Catherine, Biela, Alexandre, Vandeputte, Alexandre, Heumel, Séverine, Deruyter, Lucie, Dumont, Julie, Leroux, Florence, Engelmann, Ilka, Alidjinou, Enagnon Kazali, Hober, Didier, Brodin, Priscille, Beghyn, Terence, Trottein, François, Deprez, Benoit, Dubuisson, Jean

“…Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in…”
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Large-scale deep learning identifies the antiviral potential of PKI-179 and MTI-31 against coronaviruses by van der Horst, Demi, Carter-Timofte, Madalina E., Danneels, Adeline, Silva da Costa, Leandro, Kurmasheva, Naziia, Thielke, Anne L., Hansen, Anne Louise, Chorošajev, Vladimir, Holm, Christian K., Belouzard, Sandrine, de Weber, Ivan, Beny, Cedric, Olagnier, David

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to the global pandemic of Coronavirus Disease (2019) (COVID-19), underscoring the urgency…”
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Identification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C Virus by Vausselin, Thibaut, Séron, Karin, Lavie, Muriel, Mesalam, Ahmed Atef, Lemasson, Matthieu, Belouzard, Sandrine, Fénéant, Lucie, Danneels, Adeline, Rouillé, Yves, Cocquerel, Laurence, Foquet, Lander, Rosenberg, Arielle R, Wychowski, Czeslaw, Meuleman, Philip, Melnyk, Patricia, Dubuisson, Jean

“…Aminoquinolines and piperazines, linked or not, have been used successfully to treat malaria, and some molecules of this family also exhibit antiviral…”
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Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters by Delval, Lou, Hantute-Ghesquier, Aline, Sencio, Valentin, Flaman, Jean Michel, Robil, Cyril, Angulo, Fabiola Silva, Lipskaia, Larissa, Çobanoğlu, Ozmen, Lacoste, Anne-Sophie, Machelart, Arnaud, Danneels, Adeline, Corbin, Mathieu, Deruyter, Lucie, Heumel, Séverine, Idziorek, Thierry, Séron, Karin, Sauve, Florent, Bongiovanni, Antonino, Prévot, Vincent, Wolowczuk, Isabelle, Belouzard, Sandrine, Saliou, Jean-Michel, Gosset, Philippe, Bernard, David, Rouillé, Yves, Adnot, Serge, Duterque-Coquillaud, Martine, Trottein, François

“…Older age is one of the strongest risk factors for severe COVID-19. In this study, we determined whether age-associated cellular senescence contributes to the…”
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IL-12R beta 2 Is Essential for the Development of Experimental Cerebral Malaria by Fauconnier, Mathilde, Palomo, Jennifer, Bourigault, Marie-Laure, Meme, Sandra, Szeremeta, Frederic, Beloeil, Jean-Claude, Danneels, Adeline, Charron, Sabine, Rihet, Pascal, Ryffel, Bernhard, Quesniaux, Valerie FJ

“…A Th1 response is required for the development of Plasmodium berghei ANKA (PbA)-induced experimental cerebral malaria (ECM). The role of pro-Th1 IL-12 in…”
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