Search Results - "Dannals, RF"

Imaging Brain Mu-Opioid Receptors in Abstinent Cocaine Users: Time Course and Relation to Cocaine Craving by Gorelick, David A., Kim, Yu Kyeong, Bencherif, Badreddine, Boyd, Susan J., Nelson, Richard, Copersino, Marc, Endres, Christopher J., Dannals, Robert F., Frost, J. James

“…Cocaine treatment upregulates brain mu-opioid receptors (mOR) in animals. Human data regarding this phenomenon are limited. We previously used positron…”
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Gender and Age Influences on Human Brain Mu-Opioid Receptor Binding Measured by PET by Zubieta, Jon-Kar, Dannals, Robert F., Frost, J. James

“…OBJECTIVE: Both age and gender are being increasingly recognized as important factors influencing CNS structure and function. However, there are relatively few…”
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Mu-opioid receptor binding measured by [ 11C]carfentanil positron emission tomography is related to craving and mood in alcohol dependence by Bencherif, Badreddine, Wand, Gary S, McCaul, Mary E, Kim, Yu Kyeong, Ilgin, Nese, Dannals, Robert F, Frost, James J

“…The endogenous opioid system has been linked to alcohol dependence through animal and human studies. We investigated the relationship between alcohol craving…”
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Increased mu opioid receptor binding detected by PET in cocaine-dependent men is associated with cocaine craving by Zubieta, Jon-Kar, Gorelick, David A, Stauffer, Robin, Ravert, Hayden T, Dannals, Robert F, Frost, J. James

“…The endogenous opioid system has been recently implicated in the reinforcing actions of cocaine and other addictive drugs. In this study we examined mu opioid…”
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Imaging of delta- and mu-opioid receptors in temporal lobe epilepsy by positron emission tomography by Madar, I, Lesser, R P, Krauss, G, Zubieta, J K, Lever, J R, Kinter, C M, Ravert, H T, Musachio, J L, Mathews, W B, Dannals, R F, Frost, J J

“…The involvement of opioid neurotransmitter systems in seizure mechanisms is well documented. In previous positron emission tomography (PET) studies in patients…”
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PET imaging of cortical S2 serotonin receptors after stroke: lateralized changes and relationship to depression by Mayberg, H S, Robinson, R G, Wong, D F, Parikh, R, Bolduc, P, Starkstein, S E, Price, T, Dannals, R F, Links, J M, Wilson, A A

“…Patients with right-hemisphere strokes (N = 9) more than 1 year after injury had greater cortical binding of (3-N-[11C]methyl)spiperone than a similar group of…”
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Mu-opiate receptors measured by positron emission tomography are increased in temporal lobe epilepsy by Frost, J J, Mayberg, H S, Fisher, R S, Douglass, K H, Dannals, R F, Links, J M, Wilson, A A, Ravert, H T, Rosenbaum, A E, Snyder, S H

“…Neurochemical studies in animal models of epilepsy have demonstrated the importance of multiple neurotransmitters and their receptors in mediating seizures…”
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Multicompartmental analysis of [11C]-carfentanil binding to opiate receptors in humans measured by positron emission tomography by Frost, J J, Douglass, K H, Mayberg, H S, Dannals, R F, Links, J M, Wilson, A A, Ravert, H T, Crozier, W C, Wagner, Jr, H N

“…[11C]-Carfentanil is a high affinity opiate agonist that can be used to localize mu opiate receptors in humans by positron emission tomography (PET). A…”
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Positron emission tomography radioligands for the opioid system by Dannals, Robert F.

“…Opiate receptors are found in the brain, the spinal cord, some peripheral sensory neurons, and the gastrointestinal tract. Naturally occurring and synthetic…”
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Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [ C]McN5652 and [ C]DASB by MCCANN, Una D, SZABO, Zsolt, SECKIN, Esen, ROSENBLATT, Peter, MATHEWS, William B, RAVERT, Hayden T, DANNALS, Robert F, RICAURTE, George A

“…(+/-)3,4-Methylenedioxymethamphetamine (MDMA, 'Ecstasy') is a widely used illicit drug that produces toxic effects on brain serotonin axons and axon terminals…”
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Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: In vivo Imaging in Experimental Models of Prostate Cancer by FOSS, Catherine A, MEASE, Ronnie C, HONG FAN, YUCHUAN WANG, RAVEN, Hayden T, DANNALS, Robert F, OLSZEWSKI, Rafal T, HESTON, Warren D, KOZIKOWSKI, Alan P, POMPER, Martin G

“…Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein that is overexpressed in prostate cancer, including hormone-refractory and…”
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Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings by McCann, UD, Szabo, Z, Scheffel, U, Dannals, RF, Ricaurte, GA

“…(±)3,4-methylenedioxymethamphetamine (MDMA, “Ecstasy”) is a popular recreational drug that selectively damages brain serotonin (5-HT) neurons in animals at…”
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N-(4-Cyanotetrahydro-2H-pyran-4-yl) and N-(1-Cyanocyclohexyl) Derivatives of 1,5-Diarylpyrazole-3-carboxamides Showing High Affinity for 18 kDa Translocator Protein and/or Cannabinoid Receptors by Donohue, Sean R, Dannals, Robert F, Halldin, Christer, Pike, Victor W

“…In order to develop improved radioligands for imaging brain CB1 receptors with positron emission tomography (PET) based on rimonabant…”
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Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428 by McCann, Una D, Wong, Dean F, Yokoi, Fuji, Villemagne, Victor, Dannals, Robert F, Ricaurte, George A

“…Methamphetamine and methcathinone are psychostimulant drugs with high potential for abuse. In animals, methamphetamine and related drugs are known to damage…”
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Buprenorphine reduces cerebral glucose metabolism in polydrug abusers by WALSH, S. L, GILSON, S. F, SULLIVAN, J. T, CONTOREGGI, C, LONDON, E. D, JASINSKI, D. R, STAPLETON, J. M, PHILLIPS, R. L, DANNALS, R. F, SCHMIDT, J, PRESTON, K. L, GRAYSON, R, BIGELOW, G. E

“…Buprenorphine is a mixed opioid agonist-antagonist, which acts as a partial mu agonist and a kappa antagonist. The present study evaluated the acute effects of…”
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Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain by Titeler, M, Lyon, R A, Kuhar, M J, Frost, J F, Dannals, R F, Leonhardt, S, Bullock, A, Rydelek, L T, Price, D L, Struble, R G

“…[11C]Carfentanil is a potent opioid agonist currently in use as a specific PET (position emission tomography) scan radioligand for brain mu opioid receptors…”
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Regional mu-opioid receptor binding in insular cortex is decreased in bulimia nervosa and correlates inversely with fasting behavior by Bencherif, Badreddine, Guarda, Angela S, Colantuoni, Carlo, Ravert, Hayden T, Dannals, Robert F, Frost, J James

“…The endogenous opioid system of the brain has been implicated in feeding behavior. Abnormal repeated activation of this system may constitute a neural…”
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Pain activation of human supraspinal opioid pathways as demonstrated by [ 11C]-carfentanil and positron emission tomography (PET) by Bencherif, B, Fuchs, P.N, Sheth, R, Dannals, R.F, Campbell, J.N, Frost, J.J

“…The role of the supraspinal endogenous opioid system in pain processing has been investigated in this study using positron emission tomography imaging of […”
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Cognition and amyloid load in Alzheimer’s imaged with florbetapir F 18 (AV-45) PET by Rosenberg, PB, Wong, DF, Edell, S, Ross, J, Joshi, AD, Brašić, Zhou, Y, Raymont, Kumar, A, Ravert, HT, Dannals, RF, Pontecorvo, MJ, Skovronsky, DM, Lyketsos, CG

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Column-switching HPLC for the analysis of plasma in PET imaging studies by Hilton, John, Yokoi, Fuji, Dannals, Robert F, Ravert, Hayden T, Szabo, Zsolt, Wong, Dean F

“…A column-switch high performance liquid chromatography method for the analysis of 4 mL of plasma is described with six examples of chromatography of […”
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