Search Results - "Danko, Jan"
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1
Melatonin and breast cancer: Evidences from preclinical and human studies
Published in Critical reviews in oncology/hematology (01-02-2018)“…The breast cancer affects women with high mortality and morbidity worldwide. The risk is highest in the most developed world but also is markedly rising in the…”
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Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research
Published in Biomedicine & pharmacotherapy (01-12-2017)“…Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast cancer cases are of different ‘sporadic’ cell types, thus placing…”
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3
Does seed size mediate sex-specific reproduction costs in the Callosobruchus maculatus bean beetle?
Published in PloS one (12-12-2019)“…There is a trade-off between reproductive effort and adult longevity, and when resource allocation is taken into account, it is especially pronounced in…”
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4
Why the Gold Standard Approach by Mammography Demands Extension by Multiomics? Application of Liquid Biopsy miRNA Profiles to Breast Cancer Disease Management
Published in International journal of molecular sciences (13-06-2019)“…In the global context, the epidemic of breast cancer (BC) is evident for the early 21st century. Evidence shows that national mammography screening programs…”
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5
Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma in Vivo and in Vitro
Published in International journal of molecular sciences (09-04-2019)“…Naturally-occurring mixtures of phytochemicals present in plant foods are proposed to possess tumor-suppressive activities. In this work, we aimed to evaluate…”
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6
Density-dependence interacts with extrinsic mortality in shaping life histories
Published in PloS one (19-10-2017)“…The role of extrinsic mortality in shaping life histories is poorly understood. However, substantial evidence suggests that extrinsic mortality interacts with…”
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7
Predictive accuracy of the breast cancer genetic risk model based on eight common genetic variants: The BACkSIDE study
Published in Journal of biotechnology (20-06-2019)“…•Predictive performance of genetic risk model combining age had AUC value 0.728.•Age is more important than common genetic variants, showed Random Forest…”
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8
Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma
Published in Journal of cellular and molecular medicine (01-11-2017)“…It is supposed that plant functional foods, rich in phytochemicals, may potentially have preventive effects in carcinogenesis. In this study, the anticancer…”
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Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses
Published in Molecules (Basel, Switzerland) (19-03-2020)“…Comprehensive oncology research suggests an important role of phytochemicals or whole plant foods in the modulation of signaling pathways associated with…”
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10
Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury
Published in International journal of molecular sciences (15-03-2018)“…It was recently shown that the conditioned medium (CM) of mesenchymal stem cells can enhance viability of neural and glial cell populations. In the present…”
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11
Tetracalcium Phosphate Biocement Hardened with a Mixture of Phytic Acid–Phytase in the Healing Process of Osteochondral Defects in Sheep
Published in International journal of molecular sciences (01-11-2023)“…Hyaline articular cartilage has unique physiological, biological, and biomechanical properties with very limited self-healing ability, which makes the process…”
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12
DNA Methylation Status in Cancer Disease: Modulations by Plant-Derived Natural Compounds and Dietary Interventions
Published in Biomolecules (Basel, Switzerland) (18-07-2019)“…The modulation of the activity of DNA methyltransferases (DNMTs) represents a crucial epigenetic mechanism affecting gene expressions or DNA repair mechanisms…”
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13
Uncertainty of fetal fraction determination in Non-Invasive Prenatal Screening by highly polymorphic SNPs
Published in Journal of biotechnology (20-06-2019)“…•There are several methods for determining fetal fraction, including snpFF.•snpFF is based on targeted sequencing of highly polymorphic SNPs.•Individual…”
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Characterization of Properties, In Vitro and In Vivo Evaluation of Calcium Phosphate/Amino Acid Cements for Treatment of Osteochondral Defects
Published in Materials (17-01-2021)“…Novel calcium phosphate cements containing a mixture of four amino acids, glycine, proline, hydroxyproline and either lysine or arginine (CAL, CAK) were…”
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15
Different amplification patterns of 3q26 and 5p15 regions in cervical intraepithelial neoplasia and cervical cancer
Published in Annals of diagnostic pathology (01-08-2018)“…The aim of this study was to evaluate and correlate the amplification of chromosomal regions 3q26 and 5p15 in different cytological and histological subgroups…”
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PHB/CHIT Scaffold as a Promising Biopolymer in the Treatment of Osteochondral Defects-An Experimental Animal Study
Published in Polymers (11-04-2021)“…Biopolymer composites allow the creation of an optimal environment for the regeneration of chondral and osteochondral defects of articular cartilage, where…”
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17
Promoter hypermethylation of the tumor-suppressor genes RASSF1A, GSTP1 and CDH1 in endometrial cancer
Published in Oncology reports (01-12-2013)“…Endometrial cancer is a common gynecological malignancy with a good prognosis in early stages of the disease. The CpG island in the promoter region of…”
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In Vivo Study of Osteochondral Defect Regeneration Using Innovative Composite Calcium Phosphate Biocement in a Sheep Model
Published in Materials (10-08-2021)“…This study aimed to clarify the therapeutic effect and regenerative potential of the novel, amino acids-enriched acellular biocement (CAL) based on calcium…”
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19
Mutation accumulation may be a minor force in shaping life history traits
Published in PloS one (06-04-2012)“…Is senescence the adaptive result of tradeoffs between younger and older ages or the nonadaptive burden of deleterious mutations that act at older ages? To…”
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20
Mutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexual
Published in PloS one (31-10-2012)“…In a previous theoretical study we investigated whether adaptive or non-adaptive processes are more important in the evolution of senescence. We built a model…”
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