Search Results - "Danilenko, E. D"
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Production methods and properties of virus-like particles of Saccharomyces cerevisiae yeast killer strain
Published in Applied biochemistry and microbiology (01-12-2015)“…Based on the technology for producting virus-like particles of a killer strain of Saccharomyces cerevisiae Y-448 yeast, which includes stages of extraction,…”
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2
The synthesis of TNF-alpha conjugates with alendronic acid
Published in Russian journal of bioorganic chemistry (01-11-2016)“…Conjugates of recombinant human tumor necrosis factor alpha (TNFα) and alendronic acid linked through the protein sulfhydryl, carboxyl, and amino groups were…”
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3
A single blind, placebo-controlled randomized study of the safety, reactogenicity and immunogenicity of the “EpiVacCorona” Vaccine for the prevention of COVID-19, in volunteers aged 18–60 years (phase I–II)
Published in Infekt͡s︡ii͡a︡ i immunitet (01-04-2021)“…Vaccination of the population is one of the most effective countermeasures in responding to the pandemic caused by novel coronavirus infection. Therefore,…”
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4
An antitumor osteotropic agent based on tumor necrosis factor
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2016)“…An osteotropic agent based on the human recombinant tumor necrosis factor alpha (TNF-alpha) has been designed for treatment of bone metastases. It represents a…”
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5
Studying the effect of double-stranded RNA upon activity of mouse splenocytes using flow cytometry
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-04-2023)“…Ribonucleic acids (RNA), in particular, double-stranded RNAs, due to their ability to modulate innate immune responses, are of undoubted interest in view of…”
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6
Immunomodulatory properties of recombinant human granulocyte-macrophage colony-stimulating factor
Published in Medit͡s︡inskai͡a︡ immunologii͡a (05-04-2023)“…Granulocyte-macrophage colony stimulating factor (GM-CSF) is a myelopoietic growth factor that exerts pleiotropic effect not only on the differentiation of…”
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7
The Production of Soluble Human Gamma Interferon in the Escherichiacoli Expression System with a Decrease in Cultivation Temperature
Published in Applied biochemistry and microbiology (2023)“…A recombinant strain for producing human gamma interferon (IFN-γ) E. coli BL 21/pET-IFN-γ was constructed to provide a high level of its expression. A method…”
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8
Mannans: Obtaining from the cell walls of Saccharomyces cerevisiae yeast and assessing their adjuvant properties in a subunit vaccine model
Published in Acta biomedica scientifica (28-09-2024)“…Background. Polysaccharides are known to possess adjuvant properties, they are biodegradable, safe, and are of low-labor production. In this regard, the…”
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Study of the adjuvant properties of preparations containing recombinant human granulocyte-macrophage colony stimulating factor
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…The relevance of the search for new vaccine adjuvants is growing along with the increase in the number of current vaccine preparations, especially those…”
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10
Study of the adjuvant properties of beta-glucans from Saccharomyces Cerevisiae yeast
Published in Infekt͡s︡ii͡a︡ i immunitet (28-07-2024)“…To increase the effectiveness and immunogenicity of modern vaccines, especially subunit ones, it is required to use adjuvants. Polysaccharides, due to their…”
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11
Study of Ridostin Pro and Poly(I:C) as adjuvants that enhance the immunogenicity of an antitumor vaccine
Published in Sibirskiĭ onkologicheskiĭ zhurnal (04-07-2024)“…Aim of the study: to compare the antitumor efficacy and immunogenicity of vaccines with the same antigens but different adjuvants: Ridostin Pro or Poly(I:C);…”
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12
Development of Drugs Based on High-Polymeric Double-Stranded RNA for Antiviral and Antitumor Therapy
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (2019)“…—The review summarizes literature data on the development of drugs based on natural and synthetic high-polymeric double-stranded RNA (dsRNA), their antiviral,…”
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Study on Antiviral Activity and Pharmacological Safety of Double-Stranded Ribonucleic Acid for Intranasal Administration
Published in Antibiotiki i himioterapiâ (28-12-2022)“…Interferon inducers are of interest as the first line of defense against viral infections, including influenza. Double-stranded ribonucleic acid (dsRNA) for…”
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14
Development of a vaccine adjuvant based on squalene and study of its adjuvant properties
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…The use of modern subunit vaccines involves adjuvant introduction into their composition. Currently, the search for new and improvement of existing adjuvant…”
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15
Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes
Published in Medit͡s︡inskai͡a︡ immunologii͡a (10-01-2021)“…Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons…”
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16
Pharmacokinetics and Antitumor Effects of the Drug Containing TNF-α in Nanoparticles
Published in Bulletin of experimental biology and medicine (01-09-2010)“…Antitumor activity of TNF-α incorporated in nanoparticles (VLP-TNF-α) and dynamics of its accumulation and elimination from the blood and tumor tissue were…”
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HEMOSTIMULATING PROPERTIES OF THE CONJUGATES OF GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR WITH ALENDRONIC ACID
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (15-12-2022)“…The aim of the work is to evaluate the hemostimulating activity of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) conjugates…”
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INDUCTION OF APOPTOSIS IN B16 MELANOMA CELLS UNDER THE ACTION OF DRUG CONTAINING TUMOR NECROSIS FACTOR ALPHA AS A PART OF VIRUS-LIKE PARTICLES IN VITRO
Published in Sibirskiĭ onkologicheskiĭ zhurnal (02-09-2020)“…Aim: to evaluate the antitumor activity of the drug containing TNF-alpha and high-polymer double-stranded RNA (dsRNA) in the composition of virus-like…”
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19
Antitumor and Immunomodulating Effects of a Fragment of HL-60 Cell Differentiation Factor in Mice with Lewis Pulmonary Carcinoma
Published in Bulletin of experimental biology and medicine (01-02-2009)“…A six-member HLDF6 peptide, fragment of HL-60 cell differentiation factor, exhibited antimetastatic and immunomodulating effects…”
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20
CombiHIV vac vaccine which contains polypepitope B-and T-cell immunogens of HIV-1
Published in Doklady. Biochemistry and biophysics (01-04-2007)“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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