Search Results - "Danigo, Aurore"

Neuroprotective effect of angiotensin II type 2 receptor stimulation in vincristine-induced mechanical allodynia by Bessaguet, Flavien, Danigo, Aurore, Bouchenaki, Hichem, Duchesne, Mathilde, Magy, Laurent, Richard, Laurence, Sturtz, Franck, Desmoulière, Alexis, Demiot, Claire

“…Peripheral neuropathy is the major dose-limiting side effect of many currently used chemotherapies, such as vincristine (VCR). We recently demonstrated that…”
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An overview of ongoing clinical trials assessing pharmacological therapeutic strategies to manage chemotherapy‐induced peripheral neuropathy, based on preclinical studies in rodent models by Bouchenaki, Hichem, Danigo, Aurore, Sturtz, Franck, Hajj, Rodolphe, Magy, Laurent, Demiot, Claire

“…Chemotherapy‐induced peripheral neuropathy (CIPN) is a major dose‐limiting side effect induced by a variety of chemotherapeutic agents. Symptoms are mainly…”
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Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation by Bessaguet, Flavien, Danigo, Aurore, Magy, Laurent, Sturtz, Franck, Desmoulière, Alexis, Demiot, Claire

“…Sensory defects associated with small-fiber neuropathy (SFN) can lead to profound disabilities. The relationship between the sensory nervous system and…”
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Netazepide, an Antagonist of Cholecystokinin Type 2 Receptor, Prevents Vincristine-Induced Sensory Neuropathy in Mice by Bernard, Amandine, Mroué, Mohamad, Bourthoumieu, Sylvie, Boyce, Malcolm, Richard, Laurence, Sturtz, Franck, Demiot, Claire, Danigo, Aurore

“…Among the vinca-alkaloid class, vincristine is a potent chemotherapeutic agent with significant neurotoxic effects and is employed to address a wide spectrum…”
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The Cholecystokinin Type 2 Receptor, a Pharmacological Target for Pain Management by Bernard, Amandine, Danigo, Aurore, Bourthoumieu, Sylvie, Mroué, Mohamad, Desmoulière, Alexis, Sturtz, Franck, Rovini, Amandine, Demiot, Claire

“…Over the past decades, accumulating evidence has demonstrated a pivotal role of cholecystokinin type 2 receptor (CCK2R) in pain modulation. The established…”
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Ramipril Alleviates Oxaliplatin-Induced Acute Pain Syndrome in Mice by Bouchenaki, Hichem, Danigo, Aurore, Bernard, Amandine, Bessaguet, Flavien, Richard, Laurence, Sturtz, Franck, Balayssac, David, Magy, Laurent, Demiot, Claire

“…Oxaliplatin is a key drug for colorectal cancer that causes OXP-induced peripheral neuropathy, a dose-limiting effect characterized by cold and tactile…”
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Neuroprotective Effect of Polyvalent Immunoglobulins on Mouse Models of Chemotherapy-Induced Peripheral Neuropathy by Mroué, Mohamad, Bessaguet, Flavien, Nizou, Angélique, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Bourthoumieu, Sylvie, Danigo, Aurore, Demiot, Claire

“…The occurrence of neuropathic pain in chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting effect of many commonly-used anticancer…”
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The Angiotensin II Type 2 Receptor, a Target for Protection and Regeneration of the Peripheral Nervous System? by Danigo, Aurore, Rovini, Amandine, Bessaguet, Flavien, Bouchenaki, Hichem, Bernard, Amandine, Sturtz, Franck, Bourthoumieu, Sylvie, Desmoulière, Alexis, Magy, Laurent, Demiot, Claire

“…Preclinical evidence, accumulated over the past decade, indicates that the angiotensin II type 2 receptor (AT2R) stimulation exerts significant neuroprotective…”
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Neuroprotective Effect of Ramipril Is Mediated by AT2 in a Mouse MODEL of Paclitaxel-Induced Peripheral Neuropathy by Bouchenaki, Hichem, Bernard, Amandine, Bessaguet, Flavien, Frachet, Simon, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Bourthoumieu, Sylvie, Demiot, Claire, Danigo, Aurore

“…Paclitaxel (PTX)-induced peripheral neuropathy (PIPN) induces numerous symptoms affecting patient quality of life, leading to decreased doses or even to…”
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Blockade of Cholecystokinin Type 2 Receptors Prevents the Onset of Vincristine-Induced Neuropathy in Mice by Bernard, Amandine, Danigo, Aurore, Mroué, Mohamad, Rovini, Amandine, Richard, Laurence, Nizou, Angélique, Desmoulière, Alexis, Sturtz, Franck, Demiot, Claire, Bourthoumieu, Sylvie

“…Vincristine (VCR) is responsible for the onset of the VCR-induced peripheral neuropathy (VIPN), associated with neuropathic pain. Several reports have strongly…”
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Neuroprotective effect of erythropoietin against pressure ulcer in a mouse model of small fiber neuropathy by Danigo, Aurore, Magy, Laurent, Richard, Laurence, Desmoulière, Alexis, Bourthoumieu, Sylvie, Funalot, Benoît, Demiot, Claire

“…An increased risk of skin pressure ulcers (PUs) is common in patients with sensory neuropathies, including those caused by diabetes mellitus. Recombinant human…”
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A mouse model of sensory neuropathy induced by a long course of monomethyl-auristatin E treatment by Frachet, Simon, Danigo, Aurore, Duchesne, Mathilde, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Demiot, Claire

“…Antibody-drug conjugates (ADCs) are anticancer drugs consisting of a monoclonal antibody, targeting selective tumor antigens, to which has been frequently…”
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Skin innervation: important roles during normal and pathological cutaneous repair by Laverdet, Betty, Danigo, Aurore, Girard, Dorothée, Magy, Laurent, Demiot, Claire, Desmoulière, Alexis

“…The skin is a highly sensitive organ. It is densely innervated with different types of sensory nerve endings, which discriminate between pain, temperature and…”
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A reversible functional sensory neuropathy model by Danigo, Aurore, Magy, Laurent, Richard, Laurence, Sturtz, Franck, Funalot, Benoît, Demiot, Claire

“…•Systemic resiniferatoxin induced reversible thermal and mechanical hypoalgesia.•Nociception behaviors were restored three weeks after resiniferatoxin…”
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Renin-Angiotensin-System Inhibitors for the Prevention of Chemotherapy-Induced Peripheral Neuropathy: OncoToxSRA, a Preliminary Cohort Study by Frachet, Simon, Danigo, Aurore, Labriffe, Marc, Bessaguet, Flavien, Quinchard, Bianca, Deny, Nicolas, Baffert, Kim-Arthur, Deluche, Elise, Sturtz, Franck, Demiot, Claire, Magy, Laurent

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and dose-limiting adverse side effect of treatment. CIPN affects the oncological prognosis of…”
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Skin Biopsy Findings in Patients With CMT1A: Baseline Data From the CLN-PXT3003-01 Study Provide New Insights Into the Pathophysiology of the Disorder by Duchesne, Mathilde, Danigo, Aurore, Richard, Laurence, Vallat, Jean-Michel, Attarian, Shahram, Gonnaud, Pierre-Marie, Lacour, Arnaud, Péréon, Yann, Stojkovic, Tania, Nave, Klaus-Armin, Bertrand, Viviane, Nabirotchkin, Serguei, Cohen, Daniel, Demiot, Claire, Magy, Laurent

“…Abstract Charcot-Marie-Tooth disease type 1A (CMT1A), the most common form of Charcot-Marie-Tooth diseases, is a demyelinating neuropathy caused by a deletion…”
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TRPV1 in neuropathic pain: from animal models to therapeutical prospects by Danigo, Aurore, Magy, Laurent, Demiot, Claire

“…Since its cloning in 1997, functional and structural studies of TRPV1 have led to an improvement in our understanding of the mechanisms that underlie the…”
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Candesartan restores pressure-induced vasodilation and prevents skin pressure ulcer formation in diabetic mice by Danigo, Aurore, Nasser, Mohamad, Bessaguet, Flavien, Javellaud, James, Oudart, Nicole, Achard, Jean-Michel, Demiot, Claire

“…Angiotensin II type 1 receptor (AT1R) blockers have beneficial effects on neurovascular complications in diabetes and in organ's protection against ischemic…”
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Fibroblast protective effect of Royal Jelly against deleterious lipid peroxidation by-products by Bonte, Frederic, Otranto, Marcela, Danigo, Aurore, Archambault, Jean Christophe, Desmouliere, Alexis

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