Search Results - "Danielson, P E"

The Hypocretins: Hypothalamus-Specific Peptides with Neuroexcitatory Activity by De Lecea, L., Kilduff, T. S., Peyron, C., X.-B. Gao, Foye, P. E., Danielson, P. E., Fukuhara, C., Battenberg, E. L. F., Gautvik, V. T., Bartlett, F. S., Frankel, W. N., Van Den Pol, A. N., Bloom, F. E., Gautvik, K. M., Sutcliffe, J. G.

“…We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share substantial amino acid…”
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No hypothermic response to serotonin in 5-HT7 receptor knockout mice by Hedlund, P B, Danielson, P E, Thomas, E A, Slanina, K, Carson, M J, Sutcliffe, J G

“…With data from recently available selective antagonists for the 5-HT 7 receptor, it has been hypothesized that 5-hydroxytryptamine (5-HT)-induced hypothermia…”
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Antipsychotic drug treatment alters expression of mRNAs encoding lipid metabolism-related proteins by THOMAS, E. A, GEORGE, R. C, DANIELSON, P. E, NELSON, P. A, WARREN, A. J, LO, D, SUTCLIFFE, J. Gregor

“…Using an automated PCR-based genomics approach, TOtal Gene expression Analysis (TOGA), we have examined gene expression profiles of mouse striatum and frontal…”
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A cortical neuropeptide with neuronal depressant and sleep-modulating properties by de Lecea, Luis, Criado, José R, Prospero-Garcia, Óscar, Gautvik, Kaare M, Schweitzer, Paul, Danielson, Patria E, Dunlop, Charles L. M, Siggins, George R, Henriksen, Steven J, Sutcliffe, J. Gregor

“…Acetylcholine (ACh) plays a key role in the transitions between the different phases of sleep: Slow-wave sleep requires low ACh concentrations in the brain,…”
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Overview of the Most Prevalent Hypothalamus-Specific mRNAs, as Identified by Directional Tag PCR Subtraction by Gautvik, Kaare M., De Lecea, Luis, Gautvik, Vigdis T., Danielson, Patria E., Tranque, Pedro, Dopazo, Ana, Bloom, Floyd E., Sutcliffe, J. Gregor

“…We applied the directional tag PCR subtractive hybridization method to construct a rat hypothalamic cDNA library from which cerebellar and hippocampal…”
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Two Members of a Distinct Subfamily of 5-Hydroxytryptamine Receptors Differentially Expressed in Rat Brain by Erlander, Mark G., Lovenberg, Timothy W., Baron, Bruce M., de Lecea, Luis, Danielson, Patria E., Racke, Margaret, Slone, Amy L., Siegel, Barry W., Foye, Pamela E., Cannon, Keith, Burns, Jeffrey E., Sutcliffe, J. Gregor

“…We report two serotonin (5-hydroxytryptamine, 5-HT) receptors, MR22 and REC17, that belong to the G-protein-associated receptor superfamily. MR22 and REC17 are…”
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Molecular Cloning and Functional Expression of 5-HT1E-Like Rat and Human 5-Hydroxytryptamine Receptor Genes by Lovenberg, Timothy W., Erlander, Mark G., Baron, Bruce M., Racke, Margaret, Slone, Amy L., Siegel, Barry W., Craft, Cheryl M., Burns, Jeffrey E., Danielson, Patria E., Sutcliffe, J. Gregor

“…Sequential polymerase chain reaction experiments were performed to amplify a unique sequence representing a guanine nucleotide-binding protein…”
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Cloning, mRNA Expression, and Chromosomal Mapping of Mouse and Human Preprocortistatin by de Lecea, Luis, Ruiz-Lozano, Pilar, Danielson, Patria E., Peelle-Kirley, Jessica, Foye, Pamela E., Frankel, Wayne N., Sutcliffe, J.Gregor

“…Cortistatin is a 14-residue putative neuropeptide with strong structural similarity to somatostatin and is expressed predominantly in cortical GABAergic…”
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Heterogeneous expression of the triggering receptor expressed on myeloid cells‐2 on adult murine microglia by Schmid, Christoph D., Sautkulis, Lauren N., Danielson, Patria E., Cooper, Judith, Hasel, Karl W., Hilbush, Brian S., Sutcliffe, J. Gregor, Carson, Monica J.

“…Microglial activation is an early and common feature of almost all neuropathologies, including multiple sclerosis, Alzheimer's disease and mechanical injury…”
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Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene by Danielson, P E, Forss-Petter, S, Battenberg, E L, deLecea, L, Bloom, F E, Sutcliffe, J G

“…Four structurally related neuron-specific 1B426b mRNAs, designated AMY, BMY, AMZ, and BMZ, have been isolated from rat brain cDNA libraries. The four mRNAs are…”
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Antipsychotic drug treatment alters the expression of mRNAs encoding lipid metabolism-related proteins by Thomas, E A, George, R C, Danielson, P E, Nelson, P A, Warren, A J, Lo, D, Gregor Sutcliffe, J

“…Using an automated PCR-based genomics approach, TOtal Gene expression Analysis (TOGA), we have examined gene expression profiles of mouse striatum and frontal…”
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A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms by Lovenberg, T W, Baron, B M, de Lecea, L, Miller, J D, Prosser, R A, Rea, M A, Foye, P E, Racke, M, Slone, A L, Siegel, B W

“…We report the cloning and characterization of a novel serotonin receptor, designated as 5-HT7, which is coupled to the stimulation of adenylyl cyclase. 5-HT7…”
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Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system by Thomas, Elizabeth A., Cravatt, Benjamin F., Danielson, Patria E., Gilula, Norton B., Sutcliffe, J. Gregor

“…Fatty acid amide hydrolase (FAAH) is a membrane‐bound enzyme activity that degrades neuromodulatory fatty acid amides, including oleamide and anandamide. A…”
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Rhes: A Striatal-Specific Ras Homolog Related to Dexras1 by Falk, J D, Vargiu, P, Foye, P E, Usui, H, Perez, J, Danielson, P E, Lerner, D L, Bernal, J, Sutcliffe, J G

“…We have characterized an apparently full-length cDNA corresponding to a rat mRNA, SE6C, previously identified by subtractive hybridization as being expressed…”
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Identification of a photoreceptor-specific mRNA encoded by the gene responsible for retinal degeneration slow ( rds ) by Travis, Gabriel H, Brennan, Miles B, Danielson, Patria E, Kozak, Christine A, Sutcliffe, J. Gregor

“…Mutant mice homozygous for 'retinal degeneration slow' (rds/rds) are characterized phenotypically by abnormal development of photoreceptor outer segments in…”
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Cortistatin Is Expressed in a Distinct Subset of Cortical Interneurons by de Lecea, Luis, del Rio, Jose Antonio, Criado, Jose R, Alcantara, Soledad, Morales, Marisela, Danielson, Patria E, Henriksen, Steven J, Soriano, Eduardo, Sutcliffe, J. Gregor

“…Cortistatin is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin. In contrast to somatostatin, administration of cortistatin…”
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1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites by Godbout, M, Erlander, MG, Hasel, KW, Danielson, PE, Wong, KK, Battenberg, EL, Foye, PE, Bloom, FE, Sutcliffe, JG

“…We have characterized cDNA clones of 1G5, an mRNA highly enriched in the mammalian forebrain that encodes a 504-residue protein found in association with…”
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Clozapine increases apolipoprotein D expression in rodent brain: towards a mechanism for neuroleptic pharmacotherapy by Thomas, Elizabeth A., Danielson, Patria E., Nelson, P. Austin, Pribyl, Thomas M., Hilbush, Brian S., Hasel, Karl W., Sutcliffe, J. Gregor

“…In contrast to typical neuroleptic drugs, which have high affinities for dopamine D2 receptors, clozapine binds to multiple neurotransmitter receptors. The…”
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Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control by Forss-Petter, S, Danielson, P E, Catsicas, S, Battenberg, E, Price, J, Nerenberg, M, Sutcliffe, J G

“…To gain insights into transcription factors defining neuronal identity, we generated transgenic mice carrying a 1.8 kb rat neuron-specific enolase (NSE)…”
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The 5-HT5A serotonin receptor is expressed predominantly by astrocytes in which it inhibits cAMP accumulation: A mechanism for neuronal suppression of reactive astrocytes by Carson, Monica J., Thomas, Elizabeth A., Danielson, Patria E., Sutcliffe, J. Gregor

“…The mRNA for the 5‐hydroxytryptamine receptor 5‐HT5A was detected at embryonic day 18 in the rat central nervous system and peaked by postnatal day 20. At all…”
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