Search Results - "Danielsen, SA"
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Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
Published in Clinical cancer research (15-02-2018)“…Response to standard oncologic treatment is limited in colorectal cancer. The gene expression-based consensus molecular subtypes (CMS) provide a new paradigm…”
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MiR-9, -31, and -182 Deregulation Promote Proliferation and Tumor Cell Survival in Colon Cancer
Published in Neoplasia (New York, N.Y.) (01-09-2012)“…Several microRNAs (miRNAs) are known to be deregulated in colon cancer, but the mechanisms behind their potential involvement on proliferation and tumor cell…”
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Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
Published in Molecular oncology (01-09-2017)“…Patients with malignant peripheral nerve sheath tumor (MPNST), a rare soft tissue cancer associated with loss of the tumor suppressor neurofibromin (NF1), have…”
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RAS signaling in colorectal carcinomas through alterations of RAS, RAF, NF1 and/or RASSF1A
Published in Neoplasia (New York, N.Y.) (01-07-2008)“…More than half of all colorectal carcinomas are known to exhibit an activated MAPK (mitogen-activated protein kinase) pathway. The NF1 gene, a negative…”
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