Search Results - "Danielsen, E M"
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1
Lipid raft organization and function in the small intestinal brush border
Published in Journal of physiology and biochemistry (01-12-2008)“…The enterocyte brush border of the small intestine is a highly specialized membrane designed to function both as a high capacity digestive/absorptive surface…”
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2
Scavenger receptor class B type I (SR-BI) in pig enterocytes: trafficking from the brush border to lipid droplets during fat absorption
Published in Gut (01-10-2003)“…Background: Scavenger receptor class B type I (SR-BI) is known to mediate cellular uptake of cholesterol from high density lipoprotein particles and is…”
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3
Transcytosis of immunoglobulin A in the mouse enterocyte occurs through glycolipid raft- and rab17-containing compartments
Published in Gastroenterology (New York, N.Y. 1943) (01-03-1999)“…Background & Aims: Glycolipid “rafts” have been shown to play a role in apical membrane trafficking in the enterocyte. The present study characterized the…”
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4
A Transferrin-Like GPI-Linked Iron-Binding Protein in Detergent-Insoluble Noncaveolar Microdomains at the Apical Surface of Fetal Intestinal Epithelial Cells
Published in The Journal of cell biology (01-11-1995)“…A GPI-anchored 80-kD protein was found to be the major component of detergent-insoluble complexes, prepared from fetal porcine small intestine, constituting…”
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5
Dimeric Assembly of Enterocyte Brush Border Enzymes
Published in Biochemistry (Easton) (15-02-1994)“…The noncovalent, dimeric assembly of small intestinal brush border enzymes was studied by sedimentation analysis in density gradients of extracts of…”
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6
Post-translational Suppression of Expression of Intestinal Brush Border Enzymes by Fructose
Published in The Journal of biological chemistry (15-08-1989)“…The two major dietary sugars, fructose and sucrose, were found to suppress effectively the biosynthetic renewal of brush border enzymes in the gut. When…”
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7
Involvement of detergent-insoluble complexes in the intracellular transport of intestinal brush border enzymes
Published in Biochemistry (Easton) (07-02-1995)“…A number of transmembrane digestive enzymes of the porcine small intestinal brush border membrane were found to be partially Triton X-100-insoluble at 0 degree…”
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8
Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA
Published in FEBS letters (10-10-1988)“…The complete primary structure (967 amino acids) of an intestinal human aminopeptidase N (EC 3.4.11.2) was deduced from the sequence of a cDNA clone…”
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9
Apical Secretion of Apolipoproteins from Enterocytes
Published in The Journal of cell biology (01-03-1993)“…Synthesis and secretion of apolipoproteins in pig small intestine was studied by pulse-chase labeling of jejunal segments, kept in organ culture. Apo A-1 and…”
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10
Sucrase-isomaltase: An epithelial chloride channel?
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2001)“…GASTROENTEROLOGY 2001;121:741-742…”
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11
Cholesterol depletion of enterocytes. Effect on the Golgi complex and apical membrane trafficking
Published in The Journal of biological chemistry (18-02-2000)“…Intestinal brush border enzymes, including aminopeptidase N and sucrase-isomaltase, are associated with "rafts" (membrane microdomains rich in cholesterol and…”
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12
Cholera Toxin Entry into Pig Enterocytes Occurs via a Lipid Raft- and Clathrin-Dependent Mechanism
Published in Biochemistry (Easton) (25-01-2005)“…The small intestinal brush border is composed of lipid raft microdomains, but little is known about their role in the mechanism whereby cholera toxin gains…”
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13
Tyrosine sulfation, a post‐translational modification of microvillar enzymes in the small intestinal enterocyte
Published in The EMBO journal (01-10-1987)“…Protein sulfation in small intestinal epithelial cells was studied by labelling of organ cultured mucosal explants with [35S]‐sulfate. Six bands in SDS‐PAGE…”
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14
Perturbation of intestinal microvillar enzyme biosynthesis by amino acid analogs. Evidence that dimerization is required for the transport of aminopeptidase N out of the endoplasmic reticulum
Published in The Journal of biological chemistry (25-08-1990)“…The amino acid analogs canavanine, 3-hydroxynorvaline, thialysine, 6-fluorotryptophan, m-fluorotyrosine, and 2-fluorophenylalanine were incorporated into…”
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15
Lactase-phlorizin hydrolase and aminopeptidase N are differentially regulated in the small intestine of the pig
Published in Biochemical journal (01-10-1993)“…The longitudinal expression of two brush-border enzymes, lactase-phlorizin hydrolase (EC 3.2.1.23/62) and aminopeptidase N (EC 3.4.11.2), was studied in the…”
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16
Biosynthesis of intestinal microvillar proteins. Dimerization of aminopeptidase N and lactase-phlorizin hydrolase
Published in Biochemistry (Easton) (09-01-1990)“…The pig intestinal brush border enzymes aminopeptidase N (EC 3.4.11.2) and lactase-phlorizin hydrolase (EC 3.2.1.23-62) are present in the microvillar membrane…”
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17
Lipid Rafts Exist as Stable Cholesterol-independent Microdomains in the Brush Border Membrane of Enterocytes
Published in The Journal of biological chemistry (24-08-2001)“…Glycosphingolipid/cholesterol-rich membranes (âraftsâ)can be isolated from many types of cells, but their existence as stable microdomains in the cell…”
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18
Biosynthesis of intestinal microvillar proteins. Pulse-chase labelling studies on aminopeptidase N and sucrase-isomaltase
Published in Biochemical journal (15-06-1982)“…The biogenesis of two microvillar enzymes, aminopeptidase N (EC 3.4.11.2) and sucrase (EC 3.2.1.48)-isomaltase (EC 3.2.1.10), was studied by pulse-chase…”
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Biosynthesis of intestinal microvillar proteins. Characterization of intestinal explants in organ culture and evidence for the existence of pro-forms of the microvillar enzymes
Published in Biochemical journal (15-03-1982)“…Explants of pig small intestine were maintained at 37 degrees C in organ culture for periods up to 24 h in a system using Trowell T-8 medium supplemented with…”
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20
Localization and biosynthesis of aminopeptidase N in pig fetal small intestine
Published in Gastroenterology (New York, N.Y. 1943) (01-10-1995)“…Little is known about the expression of brush border enzymes in fetal enterocytes. The aim of this study was to describe the localization and biosynthesis of…”
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