Search Results - "Daniels, Rodney S."

Prediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses by Neher, Richard A., Bedford, Trevor, Daniels, Rodney S., Russell, Colin A., Shraiman, Boris I.

“…Human seasonal influenza viruses evolve rapidly, enabling the virus population to evade immunity and reinfect previously infected individuals. Antigenic…”
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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses by Tan, Tiong Kit, Rijal, Pramila, Rahikainen, Rolle, Keeble, Anthony H., Schimanski, Lisa, Hussain, Saira, Harvey, Ruth, Hayes, Jack W. P., Edwards, Jane C., McLean, Rebecca K., Martini, Veronica, Pedrera, Miriam, Thakur, Nazia, Conceicao, Carina, Dietrich, Isabelle, Shelton, Holly, Ludi, Anna, Wilsden, Ginette, Browning, Clare, Zagrajek, Adrian K., Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Hollinghurst, Philippa, Tully, Matthew, Moffat, Katy, Chiu, Chris, Waters, Ryan, Gray, Ashley, Azhar, Mehreen, Mioulet, Valerie, Newman, Joseph, Asfor, Amin S., Burman, Alison, Crossley, Sylvia, Hammond, John A., Tchilian, Elma, Charleston, Bryan, Bailey, Dalan, Tuthill, Tobias J., Graham, Simon P., Duyvesteyn, Helen M. E., Malinauskas, Tomas, Huo, Jiandong, Tree, Julia A., Buttigieg, Karen R., Owens, Raymond J., Carroll, Miles W., Daniels, Rodney S., McCauley, John W., Stuart, David I., Huang, Kuan-Ying A., Howarth, Mark, Townsend, Alain R.

“…There is need for effective and affordable vaccines against SARS-CoV-2 to tackle the ongoing pandemic. In this study, we describe a protein nanoparticle…”
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Receptor binding by an H7N9 influenza virus from humans by Xiong, Xiaoli, Martin, Stephen R., Haire, Lesley F., Wharton, Stephen A., Daniels, Rodney S., Bennett, Michael S., McCauley, John W., Collins, Patrick J., Walker, Philip A., Skehel, John J., Gamblin, Steven J.

“…An examination of the receptor-binding properties of the H7N9 virus, which has recently emerged in China, shows that the virus has acquired the ability to bind…”
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Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin by Lin, Yi Pu, Xiong, Xiaoli, Wharton, Stephen A., Martin, Stephen R., Coombs, Peter J., Vachieri, Sebastien G., Christodoulou, Evangelos, Walker, Philip A., Liu, Junfeng, Skehel, John J., Gamblin, Steven J., Hay, Alan J., Daniels, Rodney S., McCauley, John W.

“…The hemagglutinin (HA) of influenza A(H3N2) virus responsible for the 1968 influenza pandemic derived from an avian virus. On introduction into humans, its…”
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Genome-wide evolutionary dynamics of influenza B viruses on a global scale by Langat, Pinky, Raghwani, Jayna, Dudas, Gytis, Bowden, Thomas A, Edwards, Stephanie, Gall, Astrid, Bedford, Trevor, Rambaut, Andrew, Daniels, Rodney S, Russell, Colin A, Pybus, Oliver G, McCauley, John, Kellam, Paul, Watson, Simon J

“…The global-scale epidemiology and genome-wide evolutionary dynamics of influenza B remain poorly understood compared with influenza A viruses. We compiled a…”
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Breadth and function of antibody response to acute SARS-CoV-2 infection in humans by Huang, Kuan-Ying A, Tan, Tiong Kit, Chen, Ting-Hua, Huang, Chung-Guei, Harvey, Ruth, Hussain, Saira, Chen, Cheng-Pin, Harding, Adam, Gilbert-Jaramillo, Javier, Liu, Xu, Knight, Michael, Schimanski, Lisa, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Jan, Jia-Tsrong, Ma, Che, James, William, Daniels, Rodney S, McCauley, John W, Rijal, Pramila, Townsend, Alain R

“…Serological and plasmablast responses and plasmablast-derived IgG monoclonal antibodies (MAbs) have been analysed in three COVID-19 patients with different…”
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Molecular Characterization of Influenza C Viruses from Outbreaks in Hong Kong SAR, China by Daniels, Rodney S, Tse, Herman, Ermetal, Burcu, Xiang, Zheng, Jackson, Deborah J, Guntoro, Jeremy, Nicod, Jérôme, Stewart, Aengus, Cross, Karen J, Hussain, Saira, McCauley, John W, Lo, Janice

“…In 2014, the Centre for Health Protection in Hong Kong introduced screening for influenza C virus (ICV) as part of its routine surveillance for infectious…”
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Detection of Influenza C Virus Infection among Hospitalized Patients, Cameroon by Njouom, Richard, Monamele, Gwladys Chavely, Ermetal, Burcu, Tchatchouang, Serge, Moyo-Tetang, Sylvie, McCauley, John W, Daniels, Rodney S

“…We report 3 cases of influenza C virus in children hospitalized with severe acute respiratory infection in Cameroon. Two of these case-patients had grave…”
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A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses by Harvey, William T, Davies, Vinny, Daniels, Rodney S, Whittaker, Lynne, Gregory, Victoria, Hay, Alan J, Husmeier, Dirk, McCauley, John W, Reeve, Richard

“…Surface antigens of pathogens are commonly targeted by vaccine-elicited antibodies but antigenic variability, notably in RNA viruses such as influenza, HIV and…”
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Identification of Low- and High-Impact Hemagglutinin Amino Acid Substitutions That Drive Antigenic Drift of Influenza A(H1N1) Viruses by Harvey, William T, Benton, Donald J, Gregory, Victoria, Hall, James P J, Daniels, Rodney S, Bedford, Trevor, Haydon, Daniel T, Hay, Alan J, McCauley, John W, Reeve, Richard

“…Determining phenotype from genetic data is a fundamental challenge. Identification of emerging antigenic variants among circulating influenza viruses is…”
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The characteristics and antigenic properties of recently emerged subclade 3C.3a and 3C.2a human influenza A(H3N2) viruses passaged in MDCK cells by Lin, Yipu, Wharton, Stephen A., Whittaker, Lynne, Dai, Mian, Ermetal, Burcu, Lo, Janice, Pontoriero, Andrea, Baumeister, Elsa, Daniels, Rodney S., McCauley, John W.

“…Background Two new subclades of influenza A(H3N2) viruses became prominent during the 2014‐2015 Northern Hemisphere influenza season. The HA glycoproteins of…”
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Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Bonnet-Di Placido, Marie, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…Pigs are natural hosts for the same subtypes of influenza A viruses as humans and integrally involved in virus evolution with frequent interspecies…”
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Imprinted Anti-Hemagglutinin and Anti-Neuraminidase Antibody Responses after Childhood Infections of A(H1N1) and A(H1N1)pdm09 Influenza Viruses by Daulagala, Pavithra, Mann, Brian R, Leung, Kathy, Lau, Eric H Y, Yung, Louise, Lei, Ruipeng, Nizami, Sarea I N, Wu, Joseph T, Chiu, Susan S, Daniels, Rodney S, Wu, Nicholas C, Wentworth, David, Peiris, Malik, Yen, Hui-Ling

“…Immune imprinting is a driver known to shape the anti-hemagglutinin (HA) antibody landscape of individuals born within the same birth cohort. With the HA and…”
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Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce Lung Pathology but Do Not Prevent Virus Shedding by Paudyal, Basudev, McNee, Adam, Rijal, Pramila, Carr, B Veronica, Nunez, Alejandro, McCauley, John, Daniels, Rodney S, Townsend, Alain R, Hammond, John A, Tchilian, Elma

“…We have established the pig, a large natural host animal for influenza, with many physiological similarities to humans, as a robust model for testing the…”
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Overview of three influenza seasons in Georgia, 2014-2017 by Machablishvili, Ann, Chakhunashvili, Giorgi, Zakhashvili, Khatuna, Karseladze, Irakli, Tarkhan-Mouravi, Olgha, Gavashelidze, Mari, Jashiashvili, Tamar, Sabadze, Lela, Imnadze, Paata, Daniels, Rodney S, Ermetal, Burcu, McCauley, John W

“…Influenza epidemiological and virologic data from Georgia are limited. We aimed to present Influenza Like Illness (ILI) and Severe Acute Respiratory Infection…”
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Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans by Huang, Kuan-Ying A, Tan, Tiong Kit, Chen, Ting-Hua, Huang, Chung-Guei, Harvey, Ruth, Hussain, Saira, Chen, Cheng-Pin, Harding, Adam, Gilbert-Jaramillo, Javier, Liu, Xu, Knight, Michael, Schimanski, Lisa, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Jan, Jia-Tsrong, Ma, Che, James, William, Daniels, Rodney S, McCauley, John W, Rijal, Pramila, Townsend, Alain R

“…[This corrects the article DOI: 10.1371/journal.ppat.1009352.]…”
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Correction: Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Placido, Marie Bonnet-Di, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…[This corrects the article DOI: 10.1371/journal.ppat.1009330.]…”
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A Novel I221L Substitution in Neuraminidase Confers High-Level Resistance to Oseltamivir in Influenza B Viruses by Escuret, Vanessa, Collins, Patrick J., Casalegno, Jean-Sébastien, Vachieri, Sebastien G., Cattle, Nicholas, Ferraris, Olivier, Sabatier, Murielle, Frobert, Emilie, Caro, Valérie, Skehel, John J., Gamblin, Steve, Valla, Frédéric, Valette, Martine, Ottmann, Michèle, McCauley, John W., Daniels, Rodney S., Lina, Bruno

“…Influenza B viruses with a novel I221L substitution in neuraminidase (NA) conferring high-level resistance to oseltamivir were isolated from an…”
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Antigenic characterization of influenza viruses produced using synthetic DNA and novel backbones by Suphaphiphat, Pirada, Whittaker, Lynne, De Souza, Ivna, Daniels, Rodney S, Dormitzer, Philip R, McCauley, John W, Settembre, Ethan C

“…Highlights • Synthetic influenza viruses are antigenically similar to conventional reference viruses. • Use of novel backbones does not affect antigenic…”
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Diversity in the Circulation of Influenza A(H3N2) Viruses in the Northern Hemisphere in the 2018-19 Season by Pando, Rakefet, Stern, Shahar, Nemet, Ital, Glatman-Freedman, Aharona, Sefty, Hanna, Zuckerman, Neta S, Drori, Yaron, Friedman, Nehemya, McCauley, John W, Keinan-Boker, Lital, Mendelson, Ella, Daniels, Rodney S, Mandelboim, Michal

“…While vaccination is considered the most effective means to prevent influenza infection, its seasonal effectiveness varies, depending on the circulating…”
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