Search Results - "Danielle L. Ippolito"
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1
Vitamin D deficiency in early pregnancy
Published in PloS one (21-04-2015)“…Vitamin D deficiency is a common problem in reproductive-aged women in the United States. The effect of vitamin D deficiency in pregnancy is unknown, but has…”
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2
Predicting Rat and Human Pregnane X Receptor Activators Using Bayesian Classification Models
Published in Chemical research in toxicology (17-10-2016)“…The pregnane X receptor (PXR) is a ligand-activated transcription factor that acts as a master regulator of metabolizing enzymes and transporters. To avoid…”
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3
Alterations in tissue microRNA after heat stress in the conscious rat: potential biomarkers of organ-specific injury
Published in BMC genomics (15-02-2019)“…Heat illness remains a significant cause of morbidity in susceptible populations. Recent research elucidating the cellular mechanism of heat stress leading to…”
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4
Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor
Published in Molecular systems biology (01-12-2009)“…Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To…”
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5
Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides
Published in Toxicology (Amsterdam) (18-01-2016)“…Abstract Chlorpyrifos (CPF), an organophosphorus pesticide (OP), is one of the most widely used pesticides in the world. Subchronic exposures to CPF that do…”
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6
Systems level analysis and identification of pathways and networks associated with liver fibrosis
Published in PloS one (07-11-2014)“…Toxic liver injury causes necrosis and fibrosis, which may lead to cirrhosis and liver failure. Despite recent progress in understanding the mechanism of liver…”
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7
Longitudinal Proteomic Analysis of Plasma across Healthy Pregnancies Reveals Indicators of Gestational Age
Published in International journal of molecular sciences (01-07-2022)“…Longitudinal changes in the blood proteome during gestation relate to fetal development and maternal homeostasis. Charting the maternal blood proteome in…”
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8
Alteration in circulating metabolites during and after heat stress in the conscious rat: potential biomarkers of exposure and organ-specific injury
Published in BMC physiology (24-12-2014)“…Heat illness is a debilitating and potentially life-threatening condition. Limited data are available to identify individuals with heat illness at greatest…”
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9
Characterization of chemically induced liver injuries using gene co-expression modules
Published in PloS one (16-09-2014)“…Liver injuries due to ingestion or exposure to chemicals and industrial toxicants pose a serious health risk that may be hard to assess due to a lack of…”
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10
Correction: The orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor
Published in Cell death & disease (30-06-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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11
Group B streptococcus serotype prevalence in reproductive-age women at a tertiary care military medical center relative to global serotype distribution
Published in BMC infectious diseases (24-11-2010)“…Group B Streptococcus (GBS) serotype (Ia, Ib, II-IX) correlates with pathogen virulence and clinical prognosis. Epidemiological studies of seroprevalence are…”
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12
Transcriptional Analysis of Novel Hormone Receptors PGRMC1 and PGRMC2 as Potential Biomarkers of Breast Adenocarcinoma Staging
Published in The Journal of surgical research (01-12-2011)“…Background The expression of progesterone receptor membrane component 1 (PGRMC1) in breast cancer has generated interest in this recently discovered protein…”
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13
Intramuscular 17α-hydroxyprogesterone caproate administration attenuates immunoresponsiveness of maternal peripheral blood mononuclear cells
Published in American journal of obstetrics and gynecology (01-12-2010)“…Objective 17α-hydroxyprogesterone caproate (17P) may decrease risk of prematurity by suppressing maternal immunity. We hypothesized that in vivo 17P treatment…”
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14
The effect of magnesium sulfate on the activity of matrix metalloproteinase-9 in fetal cord plasma and human umbilical vein endothelial cells
Published in American journal of obstetrics and gynecology (01-10-2010)“…Objective Clinical evidence suggests that magnesium sulfate may reduce the risk of fetal neurologic injury in preterm delivery. Matrix metalloproteinase-9…”
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Journal Article Conference Proceeding -
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Downregulation of Fasting-Induced cAMP Response Element-Mediated Gene Induction by Leptin in Neuropeptide Y Neurons of the Arcuate Nucleus
Published in The Journal of neuroscience (15-02-2001)“…States of increased metabolic demand such as fasting modulate hypothalamic neuropeptide gene expression and decrease circulating leptin levels. This study…”
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Genome-wide gene expression profiling of acute metal exposures in male zebrafish
Published in Genomics data (01-12-2014)“…To capture global responses to metal poisoning and mechanistic insights into metal toxicity, gene expression changes were evaluated in whole adult male…”
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Mining kidney toxicogenomic data by using gene co-expression modules
Published in BMC genomics (10-10-2016)“…Acute kidney injury (AKI) caused by drug and toxicant ingestion is a serious clinical condition associated with high mortality rates. We currently lack…”
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18
Far-Forward Diagnostics in Toxic Industrial Chemical and Material Exposure Scenarios and Biomarker Identification
Published in Journal of occupational and environmental medicine (01-11-2017)“…This study describes key technical solutions for detecting environmental toxicants and diagnosing adverse health effects in military operational settings as…”
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19
Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase
Published in The Journal of neuroscience (07-03-2007)“…Partial sciatic nerve ligation (pSNL) markedly increased glial fibrillary acidic protein immunoreactivity (GFAP-IR) 1 week after lesion in the L4-L5 spinal…”
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Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis
Published in Toxicological sciences (01-01-2016)“…Toxic industrial chemicals induce liver injury, which is difficult to diagnose without invasive procedures. Identifying indicators of end organ injury can…”
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