Search Results - "Daniela Di, Pinto"
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Osteosarcoma in Children: Not Only Chemotherapy
Published in Pharmaceuticals (Basel, Switzerland) (13-09-2021)“…Osteosarcoma (OS) is the most severe bone malignant tumor, responsible for altered osteoid deposition and with a high rate of metastasis. It is characterized…”
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The Role of Mifamurtide in Chemotherapy-induced Osteoporosis of Children with Osteosarcoma
Published in Current cancer drug targets (01-01-2017)“…Osteosarcoma is the most frequent malignant bone tumor in childhood and young adulthood. Long-term survivors of osteosarcoma patients show high prevalence of…”
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Curcumin and Methotrexate: A Promising Combination for Osteosarcoma Treatment via Hedgehog Pathway Inhibition
Published in International journal of molecular sciences (21-10-2024)“…Osteosarcoma (OS) is the most severe bone tumor in children. A chemotherapy regimen includes a combination of high-dose Methotrexate (MTX), doxorubicin, and…”
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Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells
Published in Oncotarget (18-02-2020)“…Tumor-associated macrophages and their alternative activation states together with cytokines and growth factors trapped in tumor microenvironment contribute to…”
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Osteoporosis in Childhood Cancer Survivors: Physiopathology, Prevention, Therapy and Future Perspectives
Published in Cancers (06-09-2022)“…The improvement of chemotherapy, radiotherapy, and surgical interventions, together with hematopoietic stem cell transplantation, increased childhood cancer…”
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Alteration of osteoclast activity in childhood cancer survivors: Role of iron and of CB2/TRPV1 receptors
Published in PloS one (21-07-2022)“…Childhood cancer survivors (CCS) are predisposed to the onset of osteoporosis (OP). It is known that iron overload induces osteoclasts (OCs) overactivity and…”
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Biological Aspects of Inflamm-Aging in Childhood Cancer Survivors
Published in Cancers (30-09-2021)“…Anti-cancer treatments improve survival in children with cancer. A total of 80% of children treated for childhood cancer achieve 5-year survival, becoming…”
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Can Denosumab be used in combination with Doxorubicin in Osteosarcoma?
Published in Oncotarget (14-07-2020)“…Osteosarcoma is an aggressive bone tumor of the pediatric age. It is therefore important to improve conventional therapies (chemotherapy and surgery)…”
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Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia
Published in Oncotarget (06-07-2021)“…Pediatric acute myeloid leukemia (AML) represents 20% of total childhood leukemia diagnoses and is characterized by poor prognosis with a long-term survival…”
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Effect of CB2 Stimulation on Gene Expression in Pediatric B-Acute Lymphoblastic Leukemia: New Possible Targets
Published in International journal of molecular sciences (01-08-2022)“…Acute lymphoblastic leukemia type B (B-ALL) is the most common kind of pediatric leukemia, characterized by the clonal proliferation of type B lymphoid stem…”
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Safety of Anticancer Agents Used in Children: A Focus on Their Off-Label Use Through Data From the Spontaneous Reporting System
Published in Frontiers in pharmacology (07-05-2020)“…Among factors influencing the higher risk of developing unknown or rare adverse drug reactions (ADRs) among children and adolescents, there is the frequent…”
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Effects of Iron Chelation in Osteosarcoma
Published in Current cancer drug targets (01-01-2021)“…Osteosarcoma is an aggressive bone tumor. It represents the principal cause of cancer-associated death in children. Considering the recent findings on the role…”
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High EZH2 expression is correlated to metastatic disease in pediatric soft tissue sarcomas
Published in Cancer cell international (28-07-2016)“…Enhancer of Zeste Drosophila Homologue 2 (EZH2) is a key regulator of transcription as a member of polycomb repressive complex 2 (PRC2) which exerts repression…”
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Unusual association of non-anaplastic Wilms tumor and Cornelia de Lange syndrome: case report
Published in BMC cancer (13-06-2016)“…Cornelia de Lange syndrome is the prototype for cohesinopathy disorders, which are characterized by defects in chromosome segregation. Kidney malformations,…”
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Poikiloderma With Neutropenia and Mastocytosis: A Case Report and a Review of Dermatological Signs
Published in Frontiers in medicine (10-06-2021)“…Poikiloderma with neutropenia (PN) is a very rare genetic disorder mainly characterized by poikiloderma and congenital neutropenia, which explains the…”
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Osteonecrosis as a complication in pediatric patients with acute lymphoblastic leukemia
Published in La Pediatria medica e chirurgica (28-11-2016)“…Osteonecrosis is a significant adverse effect of treatment administered to children suffering from acute lymphoblastic leukemia (ALL) that may have a negative…”
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Time trends of cancer incidence in childhood in Campania region: 25 years of observation
Published in Italian journal of pediatrics (06-09-2016)“…Childhood cancer is relatively uncommon and the European age-standardized rate was 164 new case per million per year among children 0 to 14 years of age (95 %…”
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Bortezomib and endocannabinoid/endovanilloid system: a synergism in osteosarcoma
Published in Pharmacological research (01-11-2018)“…[Display omitted] Osteosarcoma is the most common primary malignant tumor of bone in children and adolescents. Bortezomib (BTZ) is an approved anticancer drug,…”
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Anti-proliferative, pro-apoptotic and anti-invasive effect of EC/EV system in human osteosarcoma
Published in Oncotarget (15-08-2017)“…Osteosarcoma is the most common and aggressive bone tumor in children. The Endocannabinoid/Endovanilloid system has been proposed as anticancer target in tumor…”
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