Search Results - "Daniel Rech"
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Occupational exposure to pesticides dysregulates systemic Th1/Th2/Th17 cytokines and correlates with poor clinical outcomes in breast cancer patients
Published in Frontiers in immunology (24-10-2023)“…Pesticides are compounds known to cause immunetoxicity in exposed individuals, which have a potential to substantially modify the prognosis of pathologies…”
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Somatic DNA Damage Response and Homologous Repair Gene Alterations and Its Association With Tumor Variant Burden in Breast Cancer Patients With Occupational Exposure to Pesticides
Published in Frontiers in oncology (08-07-2022)“…Homologous recombination is a crucial pathway that is specialized in repairing double-strand breaks; thus, alterations in genes of this pathway may lead to…”
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Toxicoproteomics Disclose Pesticides as Downregulators of TNF-α, IL-1β and Estrogen Receptor Pathways in Breast Cancer Women Chronically Exposed
Published in Frontiers in oncology (28-08-2020)“…Deleterious effects have been widely associated with chronic pesticide exposure, including cancer development. In spite of several known consequences that…”
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Hereditary Breast and Ovarian Cancer Screening Syndrome Profile in Women Diagnosed with Breast Cancer from Paraná State Southwest
Published in Revista Brasileira de ginecologia e obstetrícia (01-08-2021)“…This study evaluated the risk of the hereditary breast and ovarian cancer (HBOC) syndrome in patients with breast cancer by using the Family History Screening…”
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Influence of exogenous opioids on the acute inflammatory response in the perioperative period of oncological surgery: a clinical study
Published in Brazilian journal of anesthesiology (Elsevier) (01-01-2024)“…Recently, opioids have been related to trigger changes in cytokine release and tumor angiogenesis processes, influencing tumor growth, metastasis, and…”
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Brief research report pesticide occupational exposure leads to significant inflammatory changes in normal mammary breast tissue
Published in Frontiers in public health (14-09-2023)“…Studies have documented the high occurrence of several tumors, including female breast cancer, in populations occupationally exposed to pesticides worldwide…”
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Characterization of occupational exposure to pesticides and its impact on the health of rural women
Published in Revista de ciências farmacêuticas básica e aplicada (2022)“…Objective: To characterize the profile of occupational exposure to pesticides and its impact on women’s health. Method: This is a prospective and descriptive…”
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Excess body weight significantly affects systemic and tumor inflammatory status and correlates to poor prognosis parameters in patients with breast cancer
Published in Current research in immunology (01-01-2023)“…Obesity is a pro-inflammatory disease critical for developing breast cancer (BC), which impacts the profiles of systemic inflammatory mediators and…”
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Salivary and plasmatic levels of tumor necrosis factor‐alpha do not correlate with the clinicopathological profile in breast cancer patients
Published in Precision medical sciences (01-12-2022)“…Herein, we evaluated the salivary and plasmatic levels of tumor necrosis factor‐alpha (TNF‐α) in women diagnosed with breast cancer (BC; n = 20) versus women…”
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Impact of body mass index on the circulating levels of nitric oxide metabolites in clinicopathological features from women with breast cancer
Published in Precision medical sciences (01-06-2023)“…To investigate the clinical meaning of systemic nitric oxide metabolites (NOx) by comparing eutrophic and overweight/obese patients with breast cancer,…”
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Clinicopathological correlation between trophic-adipose levels and poor prognosis outcomes in Brazilian women diagnosed with breast cancer
Published in Brazilian Journal of Oncology (01-10-2021)“…Objective: To describe the clinicopathological profile of breast cancer patients and association with excess body weight. Methods: This was a descriptive…”
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Chronic psychological stress and its impact on the development of aggressive breast cancer
Published in Einstein (São Paulo, Brazil) (01-07-2015)“…To investigate the clinicopathological findings of women diagnosed with breast cancer and study the impact of chronic psychological stress on the pathological…”
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Carcinoma de Células de Merkel Metastático: Relato de Caso
Published in Revista Brasileira de Cancerologia (11-01-2021)“…Introdução: O carcinoma de células de Merkel é um raro tumor neuroendócrino cutâneo, que se origina das células responsáveis pela sensibilidade tátil, possui…”
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Tuberculose esofágica primária: relato de caso
Published in Revista do Colégio Brasileiro de Cirurgiões (01-10-2007)“…Esophageal tuberculosis is an extremely rare event, accounting for 0.2 percent of these cases affecting the esophagus. Most of them are secondary to pulmonary…”
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Exposure to Pesticides and Breast Cancer in an Agricultural Region in Brazil
Published in Environmental science & technology (18-06-2024)“…Rural workers are disproportionally exposed to pesticides and might be at an increased risk of developing chronic diseases. Here, we investigated the impact of…”
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Clinical implications of lipid peroxides levels in plasma and tumor tissue in breast cancer patients
Published in Prostaglandins & other lipid mediators (01-08-2022)“…Oxidative stress can promote the oxidation of lipoproteins and polyunsaturated fatty acids present in cell membranes; an event known as lipid peroxidation…”
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Anti-neutrophil antibodies (anti-MPO-ANCAs) are associated with poor prognosis in breast cancer patients
Published in Immunobiology (1979) (01-11-2020)“…p-ANCA acting as a proinflammatory molecule. In 1, autoantibodies produced against myeloperoxidase inside the tumor microenvironment promotes immunemodulation…”
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The Expression of CTLA-4 in Breast Tumors and Tumor-Infiltrating Leukocytes Affects Patients’ Systemic Inflammatory Status and Varies According to Their Molecular Subtypes
Published in Inflammation (01-10-2023)“…Recent evidence has pointed out that the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expression is a poor prognosis factor. However, the implications…”
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Occupational Exposure to Pesticides Affects Pivotal Immunologic Anti-Tumor Responses in Breast Cancer Women from the Intermediate Risk of Recurrence and Death
Published in Cancers (23-10-2022)“…Breast cancer risk stratification is a strategy based using on clinical parameters to predict patients’ risk of recurrence or death, categorized as low,…”
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