Search Results - "Daniel Ortuño-Sahagún"
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Phytochemicals That Influence Gut Microbiota as Prophylactics and for the Treatment of Obesity and Inflammatory Diseases
Published in Mediators of inflammation (01-01-2018)“…Gut microbiota (GM) plays several crucial roles in host physiology and influences several relevant functions. In more than one respect, it can be said that you…”
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Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model
Published in Frontiers in cellular neuroscience (15-08-2018)“…Cumulative evidence shows that modifications in lifestyle factors constitute an effective strategy to modulate molecular events related to neurodegenerative…”
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Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds
Published in Journal of immunology research (01-01-2015)“…The benefits of garlic to health have been proclaimed for centuries; however, only recently have Allium sativum and its derivatives been proposed as promising…”
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Alterations in Proteostasis Mechanisms in Niemann-Pick Type C Disease
Published in International journal of molecular sciences (01-04-2024)“…Niemann-Pick Type C (NPC) represents an autosomal recessive disorder with an incidence rate of 1 in 150,000 live births, classified within lysosomal storage…”
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Editorial: Epigenetic Mechanisms Regulating Neural Plasticity
Published in Frontiers in cellular neuroscience (24-04-2019)“…[...]this special issue aims to shed light on the physiological and pathological processes affected by epigenetic mechanisms that are involved in the…”
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Immunomodulatory role of decidual prolactin on the human fetal membranes and placenta
Published in Frontiers in immunology (09-06-2023)“…The close interaction between fetal and maternal cells during pregnancy requires multiple immune-endocrine mechanisms to provide the fetus with a tolerogenic…”
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Global DNA Methylation and Hydroxymethylation Levels in PBMCs Are Altered in RRMS Patients Treated with IFN-β and GA-A Preliminary Study
Published in International journal of molecular sciences (22-05-2023)“…Multiple sclerosis (MS) is a chronic disease affecting the central nervous system (CNS) due to an autoimmune attack on axonal myelin sheaths. Epigenetics is an…”
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Multiple Sclerosis and Obesity: Possible Roles of Adipokines
Published in Mediators of inflammation (01-01-2016)“…Multiple Sclerosis (MS) is an autoimmune disorder of the Central Nervous System that has been associated with several environmental factors, such as diet and…”
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Phytochemicals from Cactaceae family for cancer prevention and therapy
Published in Frontiers in pharmacology (24-10-2024)“…Cancer is a global health issue, increasingly prevalent and a leading cause of mortality. Despite extensive research, conventional treatments remain…”
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Environmental Enrichment Modified Epigenetic Mechanisms in SAMP8 Mouse Hippocampus by Reducing Oxidative Stress and Inflammaging and Achieving Neuroprotection
Published in Frontiers in aging neuroscience (18-10-2016)“…With the increase in life expectancy, aging and age-related cognitive impairments are becoming one of the most important issues for human health. At the same…”
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Expression dynamics of autophagy-related genes in the cattle tick Rhipicephalus microplus during embryonic development and under increasing larval starvation
Published in Experimental & applied acarology (01-10-2019)“…Rhipicephalus microplus is a hematophagous ectoparasite that significantly affects parasitized cattle. As a one-host tick its entire life cycle consists of…”
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Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline
Published in Frontiers in genetics (11-12-2018)“…A growing body of research shows that epigenetic mechanisms are critically involved in normal and pathological aging. The Senescence-Accelerated Mouse Prone 8…”
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Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease
Published in International journal of molecular sciences (26-03-2021)“…Niemann-Pick type C (NPC) disease is a rare autosomal recessive inherited childhood neurodegenerative disease characterized by the accumulation of cholesterol…”
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Use of Extracellular Monomeric Ubiquitin as a Therapeutic Option for Major Depressive Disorder
Published in Pharmaceuticals (Basel, Switzerland) (27-06-2024)“…Major depressive disorder (MDD) is a mood disorder that has become a global health emergency according to the World Health Organization (WHO). It affects 280…”
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Alliin, a Garlic (Allium sativum) Compound, Prevents LPS-Induced Inflammation in 3T3-L1 Adipocytes
Published in Mediators of Inflammation (01-01-2013)“…Garlic (Allium sativum L.) has been used to alleviate a variety of health problems due to its high content of organosulfur compounds and antioxidant activity…”
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Acute promyelocytic leukemia with PML/RARA (bcr1, bcr2 and bcr3) transcripts in a pediatric patient
Published in Oncology letters (01-03-2024)“…Patients with acute promyelocytic leukemia (APL) exhibit the t(15;17)(q24.1;q21.2) translocation that produces the promyelocytic leukemia (PML)/retinoic acid…”
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Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice
Published in Cells (Basel, Switzerland) (01-08-2022)“…Behavioural and psychological symptoms of dementia (BPSD) are presented in 95% of Alzheimer’s Disease (AD) patients and are also associated with neurotrophin…”
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The Human Microbiota and Obesity: A Literature Systematic Review of In Vivo Models and Technical Approaches
Published in International journal of molecular sciences (30-11-2018)“…Obesity is a noncommunicable disease that affects a considerable part of humanity. Recently, it has been recognized that gut microbiota constitutes a…”
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The Role of the miR-17-92 Cluster in Autophagy and Atherosclerosis Supports Its Link to Lysosomal Storage Diseases
Published in Cells (Basel, Switzerland) (26-09-2022)“…Establishing the role of non-coding RNA (ncRNA), especially microRNAs (miRNAs), in the regulation of cell function constitutes a current research challenge…”
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Pleiotrophin and the Expression of Its Receptors during Development of the Human Cerebellar Cortex
Published in Cells (Basel, Switzerland) (27-06-2023)“…During embryonic and fetal development, the cerebellum undergoes several histological changes that require a specific microenvironment. Pleiotrophin (PTN) has…”
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