Search Results - "Daniel, Władysława A"

Effect of diethyldithiocarbamate (DDC) and ticlopidine on CYP1A2 activity and caffeine metabolism: an in vitro comparative study with human cDNA-expressed CYP1A2 and liver microsomes by Kot, Marta, A. Daniel, Władysława

“…The aim of the present study was to test the effect of diethyldithiocarbamate (DDC), which is regarded as a cytochrome P450 (CYP) CYP2A6 and CYP2E1 inhibitor,…”
Get full text

The Novel Atypical Antipsychotic Lurasidone Affects Cytochrome P450 Expression in the Liver and Peripheral Blood Lymphocytes by Danek, Przemysław J, Daniel, Władysława A

“…Lurasidone is a novel atypical antipsychotic drug acting on dopaminergic, serotonergic and noradrenergic receptors; it is applied for the long-term treatment…”
Get full text

Contribution of human cytochrome P‐450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine by Wójcikowski, Jacek, Pichard‐Garcia, Lydiane, Maurel, Patrick, Daniel, Władysława A

“…The aim of the present study was to identify human cytochrome P‐450 isoforms (CYPs) involved in 5‐sulphoxidation and N‐demethylation of the simplest…”
Get full text

The mechanisms of interactions of psychotropic drugs with liver and brain cytochrome P450 and their significance for drug effect and drug-drug interactions by Daniel, Władysława A., Bromek, Ewa, Danek, Przemysław J., Haduch, Anna

“…[Display omitted] Cytochrome P450 (CYP) plays an important role in psychopharmacology. While liver CYP enzymes are responsible for the biotransformation of…”
Get full text

The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat by Haduch, Anna, Rysz, Marta, Papp, Mariusz, Daniel, Władysława A.

“…[Display omitted] The effect of two second-generation antidepressants escitalopram and venlafaxine on the activity of brain and liver cytochrome P450 2D…”
Get full text

The effect of new atypical antipsychotic drugs on the expression of transcription factors regulating cytochrome P450 enzymes in rat liver by Danek, Przemysław J, Daniel, Władysława A

“…Our recent studies showed that prolonged administration of novel atypical antipsychotics affected the expression and activity of cytochrome P450 (CYP), as…”
Get more information

The Effect of Chronic Iloperidone Treatment on Cytochrome P450 Expression and Activity in the Rat Liver: Involvement of Neuroendocrine Mechanisms by Danek, Przemysław J., Kuban, Wojciech, Daniel, Władysława A.

“…In order to achieve a desired therapeutic effect in schizophrenia patients and to maintain their mental wellbeing, pharmacological therapy needs to be…”
Get full text

Molecular Mechanisms of the Regulation of Liver Cytochrome P450 by Brain NMDA Receptors and via the Neuroendocrine Pathway-A Significance for New Psychotropic Therapies by Pukło, Renata, Bromek, Ewa, Haduch, Anna, Basińska-Ziobroń, Agnieszka, Kuban, Wojciech, Daniel, Władysława A

“…Recent investigations have highlighted the potential utility of the selective antagonist of the NMDA receptor GluN2B subunit for addressing major depressive…”
Get full text

Serotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone–Releasing Hormone/Growth Hormone Hormonal Pathway by Bromek, Ewa, Rysz, Marta, Haduch, Anna, Daniel, Władysława A

“…Our recent study carried out after local injection of the serotonergic neurotoxin 5,7-dihydroxytryptamine into the arcuate nucleus (ARC) of the hypothalamus…”
Get full text

Serotonin Receptors of 5-HT 2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone-Releasing Hormone/Growth Hormone Hormonal Pathway by Bromek, Ewa, Rysz, Marta, Haduch, Anna, Daniel, Władysława A

“…Our recent study carried out after local injection of the serotonergic neurotoxin 5,7-dihydroxytryptamine into the arcuate nucleus (ARC) of the hypothalamus…”
Get full text

The Effect of Chronic Treatment with Lurasidone on Rat Liver Cytochrome P450 Expression and Activity in the Chronic Mild Stress Model of Depression by Kot, Marta, Haduch, Anna, Papp, Mariusz, Daniel, Władysława A

“…Recent studies indicated an important role of the monoaminergic nervous systems (dopaminergic, noradrenergic, and serotonergic systems) and stress in the…”
Get full text

Cytochrome P450 mediates dopamine formation in the brain in vivo by Bromek, Ewa, Haduch, Anna, Gołembiowska, Krystyna, Daniel, Władysława A.

“…J. Neurochem. (2011) 118, 806–815. The cytochrome P450‐mediated synthesis of dopamine from tyramine has been shown in vitro. The aim of the present study was…”
Get full text

The Effect of Maternal High-Fat or High-Carbohydrate Diet during Pregnancy and Lactation on Cytochrome P450 2D (CYP2D) in the Liver and Brain of Rat Offspring by Kuban, Wojciech, Haduch, Anna, Bromek, Ewa, Basińska-Ziobroń, Agnieszka, Gawlińska, Kinga, Gawliński, Dawid, Filip, Małgorzata, Daniel, Władysława A

“…Cytochrome P450 2D (CYP2D) is important in psychopharmacology as it is engaged in the metabolism of drugs, neurosteroids and neurotransmitters. An unbalanced…”
Get full text

Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy by Danek, Przemysław J., Wójcikowski, Jacek, Daniel, Władysława A.

“…Antipsychotics are often used in combination with other psychotropic drugs to treat a variety of psychiatric disorders, as well as in combination with other…”
Get full text

Activation of 5-HT 1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver by Bromek, Ewa, Rysz, Marta, Haduch, Anna, Wójcikowski, Jacek, Daniel, Władysława A

“…Our recent work suggested a negative effect for the serotonergic innervation of the paraventricular nuclei (PVN) of the hypothalamus on growth hormone…”
Get full text

Chronic treatment with asenapine affects cytochrome P450 2D (CYP2D) in rat brain and liver. Pharmacological aspects by Danek, Przemysław J., Bromek, Ewa, Haduch, Anna, Daniel, Władysława A.

“…Neuroleptics have to be used for a long time to produce a therapeutic effect. Cytochrome P450 2D (CYP2D) enzymes mediate alternative pathways of…”
Get full text

Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450 by Rysz, Marta, Bromek, Ewa, Daniel, Wſadysſawa A.

“…[Display omitted] Our recent studies suggest that brain serotonergic system may be involved in the neuroendocrine regulation of cytochrome P450 expression…”
Get full text

The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats by Haduch, Anna, Bromek, Ewa, Kuban, Wojciech, Basińska-Ziobroń, Agnieszka, Danek, Przemysław J, Alenina, Natalia, Bader, Michael, Daniel, Władysława A

“…Liver cytochrome P450 (CYP) greatly contributes to the metabolism of endogenous substances and drugs. Recent studies have demonstrated that CYP expression in…”
Get more information

The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11 by Rysz, Marta, Bromek, Ewa, Haduch, Anna, Liskova, Barbora, Wójcikowski, Jacek, Daniel, Władysława A.

“…[Display omitted] Our recent work showed that the brain serotonergic system negatively regulated liver cytochrome P450. The aim of our present research was to…”
Get full text

The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats by Haduch, Anna, Pukło, Renata, Alenina, Natalia, Nikiforuk, Agnieszka, Popik, Piotr, Bader, Michael, Daniel, Władysława A.

“…Brain cytochrome P450 (CYP) contributes to the local metabolism of endogenous substrates and drugs. The aim of present study was to ascertain whether the…”
Get full text