Search Results - "Daniel, Leclair"

Optimization of Spray Drying Conditions for Yield, Particle Size and Biological Activity of Thermally Stable Viral Vectors by LeClair, Daniel A., Cranston, Emily D., Xing, Zhou, Thompson, Michael R.

“…Purpose This work examines the relevance of viral activity in the optimization of spray drying process parameters for the development of thermally stable…”
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Evaluation of excipients for enhanced thermal stabilization of a human type 5 adenoviral vector through spray drying by LeClair, Daniel A., Cranston, Emily D., Xing, Zhou, Thompson, Michael R.

“…[Display omitted] We have produced a thermally stable recombinant human type 5 adenoviral vector (AdHu5) through spray drying with three excipient formulations…”
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Stabilization of HSV-2 viral vaccine candidate by spray drying by LeClair, Daniel A., Li, Lillian, Rahman, Nausheen, Cranston, Emily D., Xing, Zhou, Thompson, Michael R.

“…[Display omitted] This work demonstrates that an HSV-2 candidate vaccine can be thermostabilized by spray drying to reduce cold chain demands. This work is…”
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Systematic Evaluation of Whole Genome Sequence-Based Predictions of Salmonella Serotype and Antimicrobial Resistance by Cooper, Ashley L, Low, Andrew J, Koziol, Adam G, Thomas, Matthew C, Leclair, Daniel, Tamber, Sandeep, Wong, Alex, Blais, Burton W, Carrillo, Catherine D

“…Whole-genome sequencing (WGS) is used increasingly in public-health laboratories for typing and characterizing foodborne pathogens. To evaluate the performance…”
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Spray dried human and chimpanzee adenoviral-vectored vaccines are thermally stable and immunogenic in vivo by Afkhami, Sam, LeClair, Daniel A, Haddadi, Siamak, Lai, Rocky, Toniolo, Steven P, Ertl, Hildegund C, Cranston, Emily D, Thompson, Michael R, Xing, Zhou

“…Highlights • Human and chimpanzee adenoviral-vectored vaccines spray dried in a sugar matrix. • Spray dried vaccine powders demonstrate thermostability and in…”
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Systematic Evaluation of Whole-Genome Sequencing Based Prediction of Antimicrobial Resistance in Campylobacter jejuni and C. coli by Hodges, Lisa M., Taboada, Eduardo N., Koziol, Adam, Mutschall, Steven, Blais, Burton W., Inglis, G. Douglas, Leclair, Daniel, Carrillo, Catherine D.

“…The increasing prevalence of antimicrobial resistance (AMR) in Campylobacter spp. is a global concern. This study evaluated the use of whole-genome sequencing…”
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Foodborne botulism in Canada, 1985-2005 by Leclair, Daniel, Fung, Joe, Isaac-Renton, Judith L, Proulx, Jean-Francois, May-Hadford, Jennifer, Ellis, Andrea, Ashton, Edie, Bekal, Sadjia, Farber, Jeffrey M, Blanchfield, Burke, Austin, John W

“…During 1985-2005, a total of 91 laboratory-confirmed outbreaks of foodborne botulism occurred in Canada; these outbreaks involved 205 cases and 11 deaths. Of…”
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Distribution of Clostridium botulinum Type E Strains in Nunavik, Northern Quebec, Canada by LECLAIR, Daniel, FARBER, Jeffrey M, DOIDGE, Bill, BLANCHFIELD, Burke, SUPPA, Sandy, PAGOTTO, Franco, AUSTIN, John W

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Consecutive Spray Drying to Produce Coated Dry Powder Vaccines Suitable for Oral Administration by LeClair, Daniel A, Cranston, Emily D, Lichty, Brian D, Xing, Zhou, Thompson, Michael R

“…Current global vaccination programs are challenged by costs associated with vaccine cold chain storage and administration. A solid, thermally stable oral…”
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Tracking sources of Clostridium botulinum type E contamination in seal meat by Leclair, Daniel, Farber, Jeffrey M., Pagotto, Franco, Suppa, Sandy, Doidge, Bill, Austin, John W.

“…Botulism in Nunavik, Quebec is associated with the consumption of aged marine mammal meat and fat. The objective was to identify meat handling practices…”
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Comparison of DNA Fingerprinting Methods for Use in Investigation of Type E Botulism Outbreaks in the Canadian Arctic by Leclair, Daniel, Pagotto, Franco, Farber, Jeffrey M, Cadieux, Brigitte, Austin, John W

“…Pulsed-field gel electrophoresis (PFGE), randomly amplified polymorphic DNA (RAPD) analysis, and automated ribotyping were compared for epidemiological typing…”
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Novel Prevention Program for Trichinellosis in Inuit Communities by Jean-François, Proulx, MacLean, J. Dick, Theresa, W. Gyorkos, Daniel, Leclair, Anne-Katrin, Richter, Bouchra, Serhir, Lorry, Forbes, Alvin, A. Gajadhar

“…Repeated outbreaks of trichinellosis caused by the consumption of Trichinella-infected walrus (Odobenus rosmarus) meat, which have sometimes led to serious…”
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Associations of processing level variables with Salmonella prevalence and concentration on broiler chicken carcasses and parts in Canada by Hardie, Kate M., Guerin, Michele T., Ellis, Andrea, Leclair, Daniel

“…A national baseline study was conducted between December 2012 and December 2013 to determine the pre-packaging prevalence and concentration of foodborne…”
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Botulism in the North: A Disease Without Borders by Austin, John W., Leclair, Daniel

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Evaluation of a Multiplex PCR Assay for the Identification of Salmonella Serovars Enteritidis and Typhimurium Using Retail and Abattoir Samples by Ogunremi, Dele, Nadin-Davis, Susan, Dupras, Andrée Ann, Márquez, Imelda Gálvan, Omidi, Katayoun, Pope, Louise, Devenish, John, Burke, Teresa, Allain, Ray, Leclair, Daniel

“…A multiplex PCR was developed to identify the two most common serovars of Salmonella causing foodborne illness in Canada, namely, serovars Enteritidis and…”
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Does incapacitation guarantee public safety? Lessons from the Massachusetts furlough and prerelease programs by LeClair, Daniel P., Guarino-Ghezzi, Susan

“…Individualized offender risk models do not account for expected reductions in risk that are caused by programmatic interventions, in part because of a…”
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Giardia duodenalis and Cryptosporidium Spp. in the Intestinal Contents of Ringed Seals (Phoca hispida) and Bearded Seals (Erignathus barbatus) in Nunavik, Quebec, Canada by Dixon, Brent R, Parrington, Lorna J, Parenteau, Monique, Leclair, Daniel, Santín, Mónica, Fayer, Ronald

“…The prevalence of Giardia duodenalis and Cryptosporidium spp. was determined for ringed and bearded seals harvested for food in the Nunavik region in northern…”
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Supervising a revolution: British ordnance committees, private inventors, and military technology in the Victorian era by LeClair, Daniel R

“…This project is a study of the changes in military technology and administration in Great Britain between 1855 and 1907. After a period of quiescence following…”
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Home Furlough Program Effects On Rates of Recidivism by LeClair, Daniel P.

“…In an effort to evaluate the effectiveness of the furlough program as a correctional device, an analysis of rates of recidivism for individuals released from…”
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Cadmium concentrations in tissues of willow ptarmigan ( Lagopus lagopus) and rock ptarmigan ( Lagopus muta) in Nunavik, Northern Québec by Rodrigue, Jean, Champoux, Louise, Leclair, Daniel, Duchesne, Jean-François

“…Willow and rock ptarmigan were obtained from Northern Québec. Willow ptarmigan were found to have mean cadmium concentrations of 179.7 μg/g (dw) in the kidneys…”
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