Search Results - "Dangol, Gita"

Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics by Yazdani, Azam, Yazdani, Akram, Elsea, Sarah H, Schaid, Daniel J, Kosorok, Michael R, Dangol, Gita, Samiei, Ahmad

“…Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains…”
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Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma by Hosein, Abdel Nasser, Dangol, Gita, Okumura, Takashi, Roszik, Jason, Rajapakshe, Kimal, Siemann, Megan, Zaid, Mohamed, Ghosh, Bidyut, Monberg, Maria, Guerrero, Paola A., Singhi, Aatur, Haymaker, Cara L., Clevers, Hans, Abou-Elkacem, Lotfi, Woermann, Sonja M., Maitra, Anirban

“…RNF43 is an E3 ubiquitin ligase that is recurrently mutated in pancreatic ductal adenocarcinoma (PDAC) and precursor cystic neoplasms of the pancreas. The…”
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Loss of Rnf43 to accelerate KRAS-mediated neoplasia in a clinically relevant genetically engineered mouse model of pancreatic adenocarcinoma by Hosein, Abdel Nasser, Dangol, Gita, Okumura, Takashi, Abou-Elkacem, Lotfi, Maitra, Anirban

“…Abstract only 733 Background: The genetic heterogeneity of pancreatic ductal adenocarcinoma (PDAC) demands a personalized molecular-targeted treatment…”
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Induction of R201C mutant G[alpha]s modifies mutant Kras-driven murine pancreatic tumorigenesis and leads to differentiated ductal phenotypes by Yamaguchi, Hiroshi, Ideno, Noboru, Dangol, Gita, Ghosh, Bidyut, Gupta, Sonal, Gutkind, Silvio J, Maitra, Anirban

“…In LGKC cells, induction of R201C Gαs followed by cAMP elevation transiently increased cell growth via Protein kinase A and Mitogen-activated protein kinase…”
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Induction of R201C mutant Gαs modifies mutant Kras-driven murine pancreatic tumorigenesis and leads to differentiated ductal phenotypes by Yamaguchi, Hiroshi, Ideno, Noboru, Dangol, Gita, Ghosh, Bidyut, Gupta, Sonal, Gutkind, Silvio J, Maitra, Anirban

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Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics by Yazdani, Azam, Yazdani, Akram, Elsea, Sarah H, Schaid, Daniel J, Kosorok, Michael R, Dangol, Gita, Samiei, Ahmad

“…Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association…”
Get full text