Search Results - "Dang, Yanna"
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Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency
Published in PLoS genetics (05-07-2022)“…The emergence of the first three lineages during development is orchestrated by a network of transcription factors, which are best characterized in mice…”
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2
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development
Published in Epigenetics (03-10-2022)“…Preimplantation development is critical for reproductive successes in mammals. Thus, it is important to understand how preimplantation embryogenesis is…”
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3
Evolutionary and Molecular Characterization of liver-enriched gene 1
Published in Scientific reports (06-03-2020)“…Liver-enriched gene 1 ( Leg1 ) is a newly identified gene with little available functional information. To evolutionarily and molecularly characterize Leg1…”
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Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development
Published in Epigenetics (02-04-2020)“…Epigenetic modifications, including DNA methylation and histone modifications, are reprogrammed considerably following fertilization during mammalian early…”
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Factors affecting early embryonic development in cattle: relevance for bovine cloning
Published in Frontiers of Agricultural Science and Engineering (2019)“…Female infertility represents a major challenge for improving the production efficiency in the dairy industry. Historically, fertility has declined whereas…”
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SIN3A Regulates Porcine Early Embryonic Development by Modulating CCNB1 Expression
Published in Frontiers in cell and developmental biology (22-02-2021)“…SIN3A is the central scaffold protein of the SIN3/histone deacetylase (HDAC) transcriptional repressor complex. SIN3A participates in the mouse preimplantation…”
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NOTCH signaling pathway is required for bovine early embryonic development
Published in Biology of reproduction (03-08-2021)“…The NOTCH signaling pathway plays an important role in regulating various biological processes, including lineage specification and apoptosis. Multiple…”
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The nucleolar protein NOP2 is required for nucleolar maturation and ribosome biogenesis during preimplantation development in mammals
Published in The FASEB journal (01-02-2020)“…The maternal nucleolus plays an indispensable role in zygotic genome activation (ZGA) and early embryonic development in mice. During oocyte‐to‐embryo…”
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Linker histone H1FOO is required for bovine preimplantation development by regulating lineage specification and chromatin structure
Published in Biology of reproduction (10-12-2022)“…Linker histone H1 binds to the nucleosome and is implicated in the regulation of the chromatin structure and function. The H1 variant H1FOO is heavily…”
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The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle
Published in Development (Cambridge) (01-06-2022)“…The genome is transcriptionally inert at fertilization and must be activated through a remarkable developmental process called zygotic genome activation (ZGA)…”
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11
KDM5-mediated redistribution of H3K4me3 is required for oocyte-to-embryonic transition in cattle
Published in Biology of reproduction (13-06-2022)“…Reprogramming of histone modifications is critical to safeguard correct gene expression profile during preimplantation development. Of interest, trimethylation…”
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Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryos
Published in Biology of reproduction (01-08-2021)“…Upon fertilization, extensive chromatin reprogramming occurs during preimplantation development. Growing evidence reveals species-dependent regulations of this…”
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13
NOTCH signaling pathway is required for bovine early embryonic development
Published in Biology of reproduction (01-08-2021)“…The NOTCH signaling pathway plays an important role in regulating various biological processes, including lineage specification and apoptosis. Multiple…”
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14
Sin3a regulates the developmental progression through morula-to-blastocyst transition via Hdac1
Published in The FASEB journal (01-11-2019)“…Suppressor interacting 3a (Sin3a) is a scaffold component of the chromatin repressive complex Sin3/histone deacetylase (Hdac). Sin3a has been shown as a hub…”
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15
Sin3a regulates the developmental progression through morula‐to‐blastocyst transition via Hdacl
Published in The FASEB journal (01-11-2019)“…Suppressor interacting 3a (Sin3a) is a scaffold component of the chromatin repressive complex Sin3/histone deacetylase (Hdac). Sin3a has been shown as a hub…”
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16
Aminopeptidase N-null neonatal piglets are protected from transmissible gastroenteritis virus but not porcine epidemic diarrhea virus
Published in Scientific reports (12-09-2019)“…Swine enteric diseases have caused significant economic loss and have been considered as the major threat to the global swine industry. Several coronaviruses,…”
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17
Identification of ADPKD-Related Genes and Pathways in Cells Overexpressing PKD2
Published in Genes (22-01-2020)“…Consistent with the gene dosage effect hypothesis, renal cysts can arise in transgenic murine models overexpressing either or , which are causal genes for…”
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18
Transcriptomic Prediction of Pig Liver-Enriched Gene 1 Functions in a Liver Cell Line
Published in Genes (10-04-2020)“…The newly identified liver-enriched gene 1 ( ) encodes a protein with a characteristic domain of unknown function 781 (DUF781/LEG1), constituting a protein…”
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The lysine deacetylase activity of HDAC1/2 is required to safeguard zygotic genome activation in mice and cattle
Published in Development (Cambridge) (16-05-2022)“…The genome is transcriptionally inert at fertilization and must be activated through a remarkable developmental process called zygotic genome activation (ZGA)…”
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