Search Results - "Dang, Thuy T"

Cytochrome P450 Enzymes as Key Drivers of Alkaloid Chemical Diversification in Plants by Nguyen, Trinh-Don, Dang, Thu-Thuy T.

“…Plants produce more than 20,000 nitrogen-containing heterocyclic metabolites called alkaloids. These chemicals serve numerous eco-physiological functions in…”
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Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina by Dang, Thu‐Thuy T., Franke, Jakob, Tatsis, Evangelos, O'Connor, Sarah E.

“…Plants create tremendous chemical diversity from a single biosynthetic intermediate. In plant‐derived ajmalan alkaloid pathways, the biosynthetic intermediate…”
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A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate by Tatsis, Evangelos C., Carqueijeiro, Inês, Dugé de Bernonville, Thomas, Franke, Jakob, Dang, Thu-Thuy T., Oudin, Audrey, Lanoue, Arnaud, Lafontaine, Florent, Stavrinides, Anna K., Clastre, Marc, Courdavault, Vincent, O’Connor, Sarah E.

“…Monoterpene indole alkaloids comprise a diverse family of over 2000 plant-produced natural products. This pathway provides an outstanding example of how nature…”
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Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes by Dang, Thu-Thuy T., Franke, Jakob, Carqueijeiro, Ines Soares Teto, Langley, Chloe, Courdavault, Vincent, O’Connor, Sarah E.

“…Cyclization reactions that create complex polycyclic scaffolds are hallmarks of alkaloid biosynthetic pathways. We present the discovery of three homologous…”
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Characterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy by Dang, Thu-Thuy T., Facchini, Peter J.

“…Noscapine is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of the Papaveraceae. It has been used as a cough…”
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Acetylation serves as a protective group in noscapine biosynthesis in opium poppy by Dang, Thu-Thuy T, Chen, Xue, Facchini, Peter J

“…Characterization of four enzymes involved in biosynthesis of the plant metabolite and anticancer agent noscapine completes this pathway and identifies an…”
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CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy by Dang, Thu-Thuy T, Facchini, Peter J

“…Noscapine is a phthalideisoquinoline alkaloid investigated for its potent pharmacological properties. Although structurally elucidated more than a century ago,…”
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Editorial: Exploring and Engineering Plant Specialized Metabolism: Latest Advances and New Horizons by Franke, Jakob, Zhang, Yang, Dang, Thu-Thuy T.

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Discovery of a cytochrome P450 enzyme catalyzing the formation of spirooxindole alkaloid scaffold by Nguyen, Tuan-Anh M, Grzech, Dagny, Chung, Khoa, Xia, Zhicheng, Nguyen, Trinh-Don, Dang, Thu-Thuy T

“…Spirooxindole alkaloids feature a unique scaffold of an oxindole ring sharing an atom with a heterocyclic moiety. These compounds display an extensive range of…”
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Board gender diversity and financial stability: Evidence from microfinance institutions by Dang, Thuy T

“…The effects of board gender diversity (BGD) on financial stability of financial institutions have long been an important topic, creating a rich strand of…”
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The relationship between central bank independence and systemic fragility: global evidence by Nguyen, Duc Nguyen, Dang, Thuy T.

“…This study investigates the relationship between central bank independence and financial stability in a global sample covering 56 countries from 1980 to 2012…”
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Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle by Caputi, Lorenzo, Franke, Jakob, Farrow, Scott C, Chung, Khoa, Payne, Richard M E, Nguyen, Trinh-Don, Dang, Thu-Thuy T, Soares Teto Carqueijeiro, Inês, Koudounas, Konstantinos, Dugé de Bernonville, Thomas, Ameyaw, Belinda, Jones, D Marc, Vieira, Ivo Jose Curcino, Courdavault, Vincent, O'Connor, Sarah E

“…Vinblastine, a potent anticancer drug, is produced by (Madagascar periwinkle) in small quantities, and heterologous reconstitution of vinblastine biosynthesis…”
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Employee-friendly practices and corporate financial performance: Evidence from a frontier market by Nguyen, Duc Nguyen, Truong, Quang Thai, Tran, Nhat Thien, Dang, Thuy T

“…This study investigates the association between employee-friendly schemes and firm financial performance using a frontier market, Vietnam, as a research…”
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Discovering and harnessing oxidative enzymes for chemoenzymatic synthesis and diversification of anticancer camptothecin analogues by Nguyen, Tuan-Anh M., Nguyen, Trinh-Don, Leung, Yuen Yee, McConnachie, Matthew, Sannikov, Oleg, Xia, Zhicheng, Dang, Thu-Thuy T.

“…Semi-synthetic derivatives of camptothecin, a quinoline alkaloid found in the Camptotheca acuminata tree, are potent anticancer agents. Here we discovered two…”
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Quantitation of Select Terpenes/Terpenoids and Nicotine Using Gas Chromatography–Mass Spectrometry with High-Temperature Headspace Sampling by Nguyen, Trinh-Don, Riordan-Short, Seamus, Dang, Thu-Thuy T, O’Brien, Rob, Noestheden, Matthew

“…Plants are the main sources of many high-value bioactive terpenoids used in the medical, fragrance, and food industries. Increasing demand for these bioactive…”
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Developing Green Bank Operation In India And Vietnam: Comparison And Evaluation by DANG, Thuy T, NGUYEN, Trang Thu

“…Purpose: The purpose of the paper is to assess the greening of investment flows as well as the orientation of financial sources of effective environmental…”
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Impact of monetary policy on private investment: Evidence from Vietnam's provincial data by Dang, Thuy T, Pham, A. D, Tran, Diem N

“…This study sheds new light on the relationship between monetary policy and private investment using Vietnam's provincial data and a system generalized method…”
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Leveraging synthetic biology and metabolic engineering to overcome obstacles in plant pathway elucidation by Kwan, Brooke D., Seligmann, Benedikt, Nguyen, Trinh-Don, Franke, Jakob, Dang, Thu-Thuy T.

“…Major hurdles in plant biosynthetic pathway elucidation and engineering include the need for rapid testing of enzyme candidates and the lack of complex…”
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Noscapine comes of age by Chen, Xue, Dang, Thu-Thuy T, Facchini, Peter J

“…Noscapine is a phthalideisoquinoline alkaloid, which represents a class of plant specialized metabolites within the large and structurally diverse group of…”
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Integration of discovery and engineering in plant alkaloid research: Recent developments in elucidation, reconstruction, and repurposing biosynthetic pathways by Bui, Van-Hung, Rodríguez-López, Carlos Eduardo, Dang, Thu-Thuy T.

“…Plants synthesize tens of thousands of bioactive nitrogen-containing compounds called alkaloids, including some clinically important drugs in modern medicine…”
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