Search Results - "Dang, Pham My‐Chan"
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Priming of the neutrophil respiratory burst: role in host defense and inflammation
Published in Immunological reviews (01-09-2016)“…Summary Neutrophils are the major circulating white blood cells in humans. They play an essential role in host defense against pathogens. In healthy…”
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NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits
Published in European journal of clinical investigation (01-11-2018)“…Neutrophils are key cells of innate immunity and during inflammation. Upon activation, they produce large amounts of superoxide anion (O2−.) and ensuing…”
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3
TLR8, but not TLR7, induces the priming of the NADPH oxidase activation in human neutrophils
Published in Journal of leukocyte biology (01-06-2015)“…TLR‐8 primes PMN ROS by inducing the phosphorylation of p47phox and p38MAPKinase, while also involving Pin1. Neutrophils play a key role in host defense…”
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NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activation
Published in The FASEB journal (01-04-2013)“…Reactive oxygen species (ROS) production by NADPH oxidase 1 (NOX1), which is mainly expressed in colon epithelial cells, requires the membrane‐bound component…”
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Phosphorylation of NADPH oxidase activator 1 (NOXA1) on serine 282 by MAP kinases and on serine 172 by protein kinase C and protein kinase A prevents NOX1 hyperactivation
Published in The FASEB journal (01-06-2010)“…NADPH oxidase activator 1 (NOXA1) together with NADPH oxidase organizer 1 (NOXO1) are key regulatory subunits of the NADPH oxidase NOX1. NOX1 is expressed…”
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Aspergillus -induced pneumonia in adult without obvious immunodeficiency: test the burst
Published in The European respiratory journal (01-04-2018)“…Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by a germline defect in one of the genes (CYBB, NCF1, CYBA, NCF2) encoding the…”
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Eugenol prevents fMLF-induced superoxide anion production in human neutrophils by inhibiting ERK1/2 signaling pathway and p47phox phosphorylation
Published in Scientific reports (06-12-2019)“…Eugenol is a polyphenol extracted from Syzygium aromaticum essential oil. It is known to have anti-inflammatory and chemoprotective properties as well as a…”
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The protein kinase A negatively regulates reactive oxygen species production by phosphorylating gp91phox/NOX2 in human neutrophils
Published in Free radical biology & medicine (20-11-2020)“…Superoxide anion production by neutrophils is essential for host defense against microbes. Superoxide anion generates other reactive oxygen species (ROS) that…”
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Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation
Published in Frontiers in immunology (23-07-2018)“…( ) is a pathogen causing significant morbidity and mortality, in particular, in hospital patients undergoing ventilation and in patients with cystic fibrosis…”
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10
Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
Published in The Journal of experimental medicine (04-11-2019)“…Neutrophils produce high levels of reactive oxygen species (ROS) by NADPH oxidase that are crucial for host defense but can lead to tissue injury when produced…”
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p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases
Published in Experimental & molecular medicine (30-04-2009)“…Phagocytes such as neutrophils play a vital role in host defense against microbial pathogens. The anti-microbial function of neutrophils is based on the…”
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NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions
Published in Mucosal immunology (2019)“…Inflammatory bowel disease (IBD) is characterized by severe and recurrent inflammation of the gastrointestinal tract, associated with altered patterns of…”
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Eugenol Inhibits Neutrophils Myeloperoxidase In Vitro and Attenuates LPS-Induced Lung Inflammation in Mice
Published in Pharmaceuticals (Basel, Switzerland) (01-04-2024)“…Eugenol (Eug) is a polyphenol extracted from the essential oil of (L.) Merr. and Perry (Myrtaceae). The health benefits of eugenol in human diseases were…”
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The Prolyl Isomerase Pin1 Controls Lipopolysaccharide-Induced Priming of NADPH Oxidase in Human Neutrophils
Published in Frontiers in immunology (01-11-2019)“…Production of superoxide anion and other reactive oxygen species (ROS) by neutrophils has a vital role in host defense against microbes. However,…”
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Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane
Published in Seminars in immunopathology (01-07-2008)“…Neutrophils play an essential role in host defense against microbial pathogens and in the inflammatory reaction. Upon activation, neutrophils produce…”
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Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: Involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase
Published in Biochemical pharmacology (01-01-2013)“…Pathways involved in zymosan-induced NADPH oxidase (NOX2) activation in human neutrophils. Reactive oxygen species (ROS) production by the neutrophil NADPH…”
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Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes
Published in Nature cell biology (01-04-2007)“…To prevent excessive degradation of internalized antigens, which could destroy the peptides recognized by T lymphocytes, dendritic cells have developed several…”
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Thymoquinone strongly inhibits fMLF-induced neutrophil functions and exhibits anti-inflammatory properties in vivo
Published in Biochemical pharmacology (15-03-2016)“…Thymoquinone, a natural product from Nigella sativa inhibits fMLF-induced human neutrophils superoxide production and granules exocytosis. [Display omitted]…”
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TNFα counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes
Published in Redox biology (01-11-2023)“…TNFα-mediated signaling pathways play a pivotal role in the pathogenesis of inflammatory diseases such as rheumatoid arthritis (RA) and inflammatory bowel…”
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Tumor Necrosis Factor-α-Induced Colitis Increases NADPH Oxidase 1 Expression, Oxidative Stress, and Neutrophil Recruitment in the Colon: Preventive Effect of Apocynin
Published in Mediators of inflammation (01-01-2014)“…Reactive oxygen species- (ROS-) mediated injury has been implicated in several inflammatory disorders, including inflammatory bowel disease (IBD). NADPH…”
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