Search Results - "Dang, Juanjuan"
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Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)
Published in Biomaterials science (25-07-2017)“…Photodynamic therapy (PDT) is considered a promising approach for the treatment of cancer and is achieved via the photosensitizer (PS)-mediated incomplete…”
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Thermal-Responsive Carbon Monoxide (CO) Delivery Expedites Metabolic Exhaustion of Cancer Cells toward Reversal of Chemotherapy Resistance
Published in ACS central science (26-06-2019)“…Multidrug resistance (MDR) is the main cause of chemotherapy failure, and the mechanism of MDR is largely associated with drug efflux mediated by the adenosine…”
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Photodynamic therapy-triggered on-demand drug release from ROS-responsive core-cross-linked micelles toward synergistic anti-cancer treatment
Published in Nano research (01-05-2019)“…Polymeric micelles have demonstrated wide utility for chemodrug delivery, which however, still suffer from shortcomings such as undesired drug loading,…”
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Carbon monoxide (CO)-Strengthened cooperative bioreductive anti-tumor therapy via mitochondrial exhaustion and hypoxia induction
Published in Biomaterials (01-07-2019)“…Bioreductive chemodrugs require hypoxic conditions to activate their anti-cancer efficacy. The insufficient and heterogeneous hypoxic condition in tumor…”
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Correlation of hysteroscopic findings of chronic endometritis with CD138 immunohistochemistry and their correlation with pregnancy outcomes
Published in Journal of assisted reproduction and genetics (01-09-2024)“…Purpose To investigate the correlation between hysteroscopic findings of chronic endometritis and CD138 immunohistochemistry positive in endometritis and to…”
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Multivalency-assisted membrane-penetrating siRNA delivery sensitizes photothermal ablation via inhibition of tumor glycolysis metabolism
Published in Biomaterials (01-12-2019)“…The success of photothermal therapy (PTT) is often hampered by the thermo-resistance of tumor cells mediated by over-expressed heat shock proteins (HSPs)…”
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Drug resistance reversal by interventing cancer bioenergetics with spherical helical polypeptide-potented gene silencing
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-06-2021)“…[Display omitted] •Reversal of drug resistance via genetic intervention of cancer bioenergetics.•Multivalency enhanced the trans-membrane siRNA delivery…”
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Cardiomyocyte-targeted anti-inflammatory nanotherapeutics against myocardial ischemia reperfusion (IR) injury
Published in Nano research (2022)“…Myocardial ischemia reperfusion (IR) injury is closely related to the overwhelming inflammation in the myocardium. Herein, cardiomyocyte-targeted…”
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Reversal of Chemoresistance via Staged Liberation of Chemodrug and siRNA in Hierarchical Response to ROS Gradient
Published in Advanced healthcare materials (01-06-2024)“…P‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR) often leads to the failure of antitumor chemotherapy, and codelivery of chemodrug with P‐gp siRNA…”
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Photodynamic therapy-mediated remote control of chemotherapy toward synergistic anticancer treatment
Published in Nanoscale (14-08-2018)“…Stimuli-responsive nanomedicine (NM) with an on-demand drug release property has demonstrated promising utility toward cancer therapy. However, sensitivity and…”
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