Search Results - "Dang, C V"

Therapeutic targeting of Myc-reprogrammed cancer cell metabolism by Dang, C V

“…Studies from many laboratories document that the MYC oncogene produces a pleiotropic transcription factor, Myc, which influences genes driven by all three RNA…”
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MYC, metabolism, cell growth, and tumorigenesis by Dang, Chi V

“…The MYC proto-oncogene is frequently activated in human cancers through a variety of mechanisms. Its deregulated expression, unconstrained by inactivation of…”
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Myc target transcriptomes by Lee, L A, Dang, C V

“…The c-Myc oncogenic transcription factor plays a central role in many human cancers through the regulation of gene expression. Although the molecular…”
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Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor by ORLOWSKI, R. Z, ESWARA, J. R, LAFOND-WALKER, A, GREVER, M. R, ORLOWSKI, M, DANG, C. V

“…Cell growth and viability are dependent on the function of the multicatalytic proteinase complex (proteasome), a multisubunit particle that affects progression…”
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Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease by BRODSKY, R. A, PETRI, M, SMITH, B. D, SEIFTER, E. J, SPIVAK, J. L, STYLER, M, DANG, C. V, BRODSKY, I, JONES, R. J

“…Immunoablative high-dose cyclophosphamide without stem-cell rescue induces durable, complete remission in most patients with aplastic anemia. To determine the…”
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Identification of the human c-myc protein nuclear translocation signal by DANG, C. V, LEE, W. M. F

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Runner's Anemia by Dang, Chi V

“…Macrocytic anemia occurring in patients with fatigue suggests numerous diagnoses, ranging from nutritional deficiencies to a myelodysplastic syndrome. A…”
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Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins by Dang, C V, Lee, W M

“…Protein import into the cell nucleus requires specific binding of nuclear proteins to the nuclear pore complex. Based on amino acid sequence “motifs” of known…”
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The interplay between MYC and HIF in the Warburg effect by Dang, C V

“…c-MYC and the hypoxia-inducible factors (HIFs) are critical factors for tumorigenesis in a large number of human cancers. While the normal function of MYC…”
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Glycosylation of the c-Myc Transactivation Domain by Chou, Teh-Ying, Dang, Chi V., Hart, Gerald W.

“…O-linked N-acetylglucosamine (O-GlcNAc) is an abundant and dynamic posttranslational modification composed of a single monosaccharide, GlcNAc, glycosidically…”
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Identification of putative c-Myc-responsive genes: characterization of rcl, a novel growth-related gene by Lewis, Brian C., Shim, Hyunsuk, Li, Qing, Wu, Chyi Sun, Lee, Linda A., Maity, Amit, Dang, Chi V.

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Discrimination Between Related DNA Sites by a Single Amino Acid Residue of Myc-Related Basic-Helix-Loop-Helix Proteins by Dang, Chi V., Dolde, Christine, Gillison, Maura L., Kato, Gregory J.

“…A yeast genetic system was developed to study how the basic regions of basic-helix-loop-helix (bHLH) proteins distinguish between related consensus bHLH…”
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Participation of Cyclin A in Myc-Induced Apoptosis by Hoang, Arthur T., Cohen, Kenneth J., Barrett, John F., Bergstrom, Donald A., Dang, Chi V.

“…The involvement of c-Myc in cellular proliferation or apoptosis has been linked to differential cyclin gene expression. We observed that in both proliferating…”
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An amino-terminal c-myc domain required for neoplastic transformation activates transcription by Kato, G J, Barrett, J, Villa-Garcia, M, Dang, C V

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Function of the c-Myc oncoprotein by Kato, G J, Dang, C V

“…The c-Myc protein, the product of the c-myc proto-oncogene, is a nuclear phosphoprotein with DNA binding properties. Deregulated c-myc expression participates…”
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Max : functional domains and interaction with c-Myc by KATO, G. J, LEE, W. M. F, CHEN, L, DANG, C. V

“…The product of the c-myc proto-oncogene is a DNA-binding protein, the deregulated expression of which is associated with a variety of malignant neoplasms. The…”
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MXI1, a putative tumor suppressor gene, suppresses growth of human glioblastoma cells by WECHSLER, D. S, SHELLY, C. A, PETROFF, C. A, DANG, C. V

“…The Mxi1 protein functions in a regulatory network with members of the c-Myc family, in which c-Myc activates transcription and stimulates cell proliferation,…”
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Oncogenic alterations of metabolism by Dang, Chi V, Semenza, Gregg L

“…Over seven decades ago, classical biochemical studies showed that tumors have altered metabolic profiles and display high rates of glucose uptake and…”
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Translocations involving c-myc and c-myc function by Boxer, L M, Dang, C V

“…c-MYC is the prototype for oncogene activation by chromosomal translocation. In contrast to the tightly regulated expression of c-myc in normal cells, c-myc is…”
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A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain by Hoang, Arthur T., Lutterbach, Bart, Lewis, Brian C., Yano, Takahiro, Chou, Teh-Ying, Barrett, John F., Raffeld, Mark, Hann, Stephen R., Dang, Chi V.

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