Search Results - "Danesin, Cathy"
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Modelling variability and heterogeneity of EMT scenarios highlights nuclear positioning and protrusions as main drivers of extrusion
Published in Nature communications (28-08-2024)“…Epithelial-Mesenchymal Transition (EMT) is a key process in physiological and pathological settings. EMT is often presented as a linear sequence with (i)…”
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Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord
Published in Scientific reports (08-01-2021)“…Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates, a critical regulation level…”
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Moving the Shh Source over Time: What Impact on Neural Cell Diversification in the Developing Spinal Cord?
Published in Journal of developmental biology (12-04-2017)“…A substantial amount of data has highlighted the crucial influence of Shh signalling on the generation of diverse classes of neurons and glial cells throughout…”
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Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord
Published in The Journal of neuroscience (12-12-2012)“…In the developing ventral spinal cord, motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) are sequentially generated from a common pool of neural…”
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Dynamics of sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring sulfatase 1
Published in Development (Cambridge) (15-03-2014)“…In the ventral spinal cord, generation of neuronal and glial cell subtypes is controlled by Sonic hedgehog (Shh). This morphogen contributes to cell diversity…”
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Ventral Neural Progenitors Switch toward an Oligodendroglial Fate in Response to Increased Sonic Hedgehog (Shh) Activity: Involvement of Sulfatase 1 in Modulating Shh Signaling in the Ventral Spinal Cord
Published in The Journal of neuroscience (10-05-2006)“…In the embryonic chick ventral spinal cord, the initial emergence of oligodendrocytes is a relatively late event that depends on prolonged Sonic hedgehog (Shh)…”
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FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord
Published in Neural development (08-03-2018)“…Most oligodendrocytes of the spinal cord originate from ventral progenitor cells of the pMN domain, characterized by expression of the transcription factor…”
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Distinct sites of origin of oligodendrocytes and somatic motoneurons in the chick spinal cord: oligodendrocytes arise from Nkx2.2-expressing progenitors by a Shh-dependent mechanism
Published in Development (Cambridge) (15-04-2001)“…In the vertebrate spinal cord, oligodendrocytes arise from the ventral part of the neuroepithelium, a region also known to generate somatic motoneurons. The…”
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Converse control of oligodendrocyte and astrocyte lineage development by Sonic hedgehog in the chick spinal cord
Published in Developmental biology (15-06-2004)“…In the developing spinal cord, oligodendrocyte progenitors (OLPs) originate from the ventral neuroepithelium and the specification of this lineage depends on…”
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Sulfatase 2 promotes generation of a spinal cord astrocyte subtype that stands out through the expression of Olig2
Published in Glia (01-08-2019)“…Generation of glial cell diversity in the developing spinal cord is known to depend on spatio‐temporal patterning programs. In particular, expression of the…”
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Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord
Published in Scientific reports (08-01-2021)“…Abstract Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates, a critical regulation…”
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Anteroposterior elongation of the chicken anterior trunk neural tube is hindered by interaction with its surrounding tissues
Published in Cells & development (01-12-2021)Get full text
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Anteroposterior elongation of the chicken anterior trunk neural tube is hindered by interaction with its surrounding tissues
Published in Cells & development (01-12-2021)“…The neural tube is the precursor of the central nervous system. Its early formation and growth are known to be extremely biased along the anteroposterior (AP)…”
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A subtractive approach to characterize genes with regionalized expression in the gliogenic ventral neuroepithelium: identification of chick Sulfatase 1 as a new oligodendrocyte lineage gene
Published in Molecular and cellular neuroscience (01-04-2004)“…To address the question of the origin of glial cells and the mechanisms leading to their specification, we have sought to identify novel genes expressed in…”
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A substractive approach to characterize genes with regionalized expression in the gliogenic ventral neuroepithelium: identification of chick Sulfatase 1 as a new oligodendrocyte lineage gene
Published in Molecular and cellular neuroscience (2004)“…To address the question of the origin of glial cells and the mechanisms leading to their specification, we have sought to identify novel genes expressed in…”
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