Search Results - "Danesh, John N."
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Shorter leukocyte telomere length is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank
Published in EBioMedicine (01-08-2021)“…Background Older age is the most powerful risk factor for adverse coronavirus disease-19 (COVID-19) outcomes. It is uncertain whether leucocyte telomere length…”
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Association of shorter leucocyte telomere length with risk of frailty
Published in Journal of cachexia, sarcopenia and muscle (01-06-2022)“…Background Frailty is a multidimensional syndrome of decline that affects multiple systems and predisposes to adverse health outcomes. Although chronological…”
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Polygenic basis and biomedical consequences of telomere length variation
Published in Nature genetics (01-10-2021)“…Telomeres, the end fragments of chromosomes, play key roles in cellular proliferation and senescence. Here we characterize the genetic architecture of…”
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Improving reporting standards for polygenic scores in risk prediction studies
Published in Nature (London) (11-03-2021)“…Polygenic risk scores (PRSs), which often aggregate results from genome-wide association studies, can bridge the gap between initial discovery efforts and…”
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Modifiable traits, healthy behaviours, and leukocyte telomere length: a population-based study in UK Biobank
Published in The Lancet. Healthy longevity (01-05-2022)“…Telomere length is associated with risk of several age-related diseases and cancers. We aimed to investigate the extent to which telomere length might be…”
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Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study
Published in BMC medicine (10-01-2020)“…Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent…”
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H. pylori and diabetes
Published in Digestive diseases and sciences (01-12-1997)Get full text
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Epidemiology of spinal cord injury in New Zealand
Published in Neuroepidemiology (1993)“…Spinal cord injury (SCI) is a catastrophic and costly result of both intentional and unintentional injury. We present data from the Health Statistics Services…”
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