Search Results - "Daneman, R."
-
1
Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
Published in Nature communications (06-06-2019)“…Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully…”
Get full text
Journal Article -
2
PDGFRβ+ cells in human and experimental neuro-vascular dysplasia and seizures
Published in Neuroscience (15-10-2015)“…Highlights • Human FCD and TLE-HS display the highest PDGFRβ+ cells immunoreactivity, at the microvasculature identifying pericytes. • Parenchymal PDGFRβ / NG2…”
Get full text
Journal Article -
3
The Gut Immune Barrier and the Blood-Brain Barrier: Are They So Different?
Published in Immunity (Cambridge, Mass.) (20-11-2009)“…In order to protect itself from a diverse set of environmental pathogens and toxins, the body has developed a number of barrier mechanisms to limit the entry…”
Get full text
Journal Article -
4
Specification of CNS macrophage subsets occurs postnatally in defined niches
Published in Nature (London) (28-04-2022)“…All tissue-resident macrophages of the central nervous system (CNS)—including parenchymal microglia, as well as CNS-associated macrophages (CAMs 1 ) such as…”
Get full text
Journal Article -
5
Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat
Published in The Journal of neuroscience (11-07-2012)“…The immaturity of the CNS at birth greatly affects injury after stroke but the contribution of the blood-brain barrier (BBB) to the differential response to…”
Get full text
Journal Article -
6
A Protein Trap Strategy to Detect GFP-Tagged Proteins Expressed from Their Endogenous Loci in Drosophila
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2001)“…In Drosophila, enhancer trap strategies allow rapid access to expression patterns, molecular data, and mutations in trapped genes. However, they do not give…”
Get full text
Journal Article -
7
Author Correction: Specification of CNS macrophage subsets occurs postnatally in defined niches
Published in Nature (London) (06-10-2022)Get full text
Journal Article -
8
The Blood-Brain Barrier— Lessons from Moody Flies
Published in Cell (07-10-2005)“…Despite the importance of the blood-brain barrier (BBB), little is known about the molecular mechanisms that control its integrity. The identification of…”
Get full text
Journal Article -
9
Tyrosine Kinases in Autoimmune Demyelination
Published in Clinical immunology (Orlando, Fla.) (01-01-2009)Get full text
Journal Article -
10
Noninvasive Measurement of the pH of the Endoplasmic Reticulum at Rest and during Calcium Release
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-1998)“…The pH within individual organelles of the secretory pathway is believed to be an important determinant of their biosynthetic activity. However, little is…”
Get full text
Journal Article -
11
In Situ Measurements of the pH of Mammalian Peroxisomes Using the Fluorescent Protein pHluorin
Published in The Journal of biological chemistry (28-12-2001)“…Peroxisomes are metabolically active organelles that participate in the oxidation of long-chain fatty acids and in the biosynthesis of bile acids, cholesterol,…”
Get full text
Journal Article -
12
Discrepancy between CYP2D6 phenotype and genotype derived from post-mortem dextromethorphan blood level
Published in Forensic science international (08-05-2000)“…Objective: To describe the death of a toddler after a therapeutic dose of dextromethorphan and its investigation. Study design: Case report, cytochrome P450…”
Get full text
Journal Article -
13
Interactions of clobazam with conventional antiepileptics in children
Published in Journal of child neurology (01-04-1997)“…Clobazam is a 1,5-benzodiazepine effective in antiepileptic therapy of children and adults. Presently it is mainly used as adjuvant therapy for intractable…”
Get more information
Journal Article -
14
The efficacy of diazepam in the treatment of acute iron overload in rats
Published in Canadian journal of physiology and pharmacology (01-09-1998)“…While conducting studies on the prevention of mortality from acute iron intoxication in rats, diazepam, given to prevent animal suffering, was observed to be…”
Get more information
Journal Article -
15
Efficacy of deferiprone in the treatment of acute iron intoxication in rats
Published in Journal of toxicology. Clinical toxicology (1996)“…Deferiprone [(1,2-dimethyl-3-hydroxypyrid-4-one) (L1)], is the first orally active iron chelating agent to reach clinical trials in patients with chronic iron…”
Get more information
Journal Article