Search Results - "Danehy, Francis T"

Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape by Martin, Constance J, Datta, Abhishek, Littlefield, Christopher, Kalra, Ashish, Chapron, Christopher, Wawersik, Stefan, Dagbay, Kevin B, Brueckner, Christopher T, Nikiforov, Anastasia, Danehy, Jr, Francis T, Streich, Jr, Frederick C, Boston, Christopher, Simpson, Allison, Jackson, Justin W, Lin, Susan, Danek, Nicole, Faucette, Ryan R, Raman, Pichai, Capili, Allan D, Buckler, Alan, Carven, Gregory J, Schürpf, Thomas

“…Despite breakthroughs achieved with cancer checkpoint blockade therapy (CBT), many patients do not respond to anti-programmed cell death-1 (PD-1) due to…”
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An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis by Jackson, Justin W, Frederick C Streich, Jr, Pal, Ajai, Coricor, George, Boston, Chris, Brueckner, Christopher T, Canonico, Kaleigh, Chapron, Christopher, Cote, Shaun, Dagbay, Kevin B, Danehy, Jr, Francis T, Kavosi, Mania, Kumar, Sandeep, Lin, Susan, Littlefield, Christopher, Looby, Kailyn, Manohar, Rohan, Martin, Constance J, Wood, Marcie, Zawadzka, Agatha, Wawersik, Stefan, Nicholls, Samantha B, Datta, Abhishek, Buckler, Alan, Schürpf, Thomas, Carven, Gregory J, Qatanani, Mohammed, Fogel, Adam I

“…Inhibitors of the transforming growth factor-β (TGF-β) pathway are potentially promising antifibrotic therapies, but nonselective simultaneous inhibition of…”
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Evaluation of the role of three candidate human kinases in the conversion of the hepatitis C virus inhibitor 2′- C-methyl-cytidine to its 5′-monophosphate metabolite by Golitsina, Nina L., Danehy, Francis T., Fellows, Ross, Cretton-Scott, Erika, Standring, David N.

“…Nucleoside analogs are effective inhibitors of the hepatitis C virus (HCV) in the clinical setting. One such molecule, 2′- C-methyl-cytidine (2′-MeC), entered…”
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Expression of multiple neuregulin transcripts in postnatal rat brains by Chen, M S, Bermingham-McDonogh, O, Danehy, Jr, F T, Nolan, C, Scherer, S S, Lucas, J, Gwynne, D, Marchionni, M A

“…The distribution of neuregulin transcripts in rat brains was studied by both RNA blotting and in situ hybridization. Our data demonstrate that multiple…”
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302-OR: The Antimyostatin Antibody SRK-439 Promotes Healthy Body Composition in Combination with GLP-1RAs in a Mouse Model of Obesity by Fulham, Melissa A, Chapron, Christopher, Danehy, Francis T, Streich, Frederick C, Liang, Brian, Boston, Christopher J, Jackson, Justin W, Huang, Yan, Nicholls, Samantha EB, Cortes, Leslie, Qatanani, Mo

“…One of the challenges with obesity treatments is maintaining a healthy body composition during weight loss; lean mass is reduced during weight loss (15%-40% of…”
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Evaluation of the role of three candidate human kinases in the conversion of the hepatitis C virus inhibitor 2a super(2)-C-methyl-cytidine to its 5a super(2)-monophosphate metabolite by Golitsina, Nina L, Danehy, Francis T, Fellows, Ross, Cretton-Scott, Erika, Standring, David N

“…Nucleoside analogs are effective inhibitors of the hepatitis C virus (HCV) in the clinical setting. One such molecule, 2a super(2)-C-methyl-cytidine (2a…”
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Evaluation of the role of three candidate human kinase in the conversion of the hepatitis C virus inhibitor 2'-C-methyl-cytidine to its 5'-monophosphate metabolite by GOLITSINA, Nina L, DANEHY, Francis T, FELLOWS, Ross, CRETTON-SCOTT, Erika, STANDRING, David N

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mRNAs for insulin-like growth factor-II (IGF-II) and variant IGF-II are co-expressed in human fetal ovary and uterus by Yeh, J, Danehy, F T, Osathanondh, R, Villa-Komaroff, L

“…Insulin-like growth factor-II (IGF-II) is postulated to have autocrine and/or paracrine functions in developing fetal tissues, but has never been reported in…”
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