Search Results - "Dandepally, Srinivasa R"

Microwave-assisted synthesis of 4-chloro- N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide (B-355252): a new potentiator of nerve growth factor (NGF)-induced neurite outgrowth by Williams, Alfred L., Dandepally, Srinivasa R., Gilyazova, Nailya, Witherspoon, Sam M., Ibeanu, Gordon

“…The synthesis of 4-chloro- N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide (B-355252) using an MW-assisted nucleophilic aromatic…”
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A synthetic analog of verbenachalcone potentiates NGF-induced neurite outgrowth and enhances cell survival in neuronal cell models by Clement, Ceiléssia M., Dandepally, Srinivasa R., Williams, Alfred L., Ibeanu, Gordon C.

“…This study uses NeuroScreen-1 (NS-1) cells, a derivative of pheochromocytoma (PC12) cells, to examine neurite outgrowth induced by a novel synthetic…”
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Neuroprotective effects of an in vitro BBB permeable phenoxythiophene sulfonamide small molecule in glutamate‑induced oxidative injury by Pokharel, Smritee, Gliyazova, Nailya S, Dandepally, Srinivasa R, Williams, Alfred L, Ibeanu, Gordon C

“…Reactive oxygen species (ROS) play a central role in oxidative stress-associated neuronal cell death during ischemia. Further investigation into the inhibition…”
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Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2) by Ahmad, Syed, St. Hilaire, Valentine R., Dandepally, Srinivasa R., Johnson, Gary L., Williams, Alfred L., Scott, John E.

“…The kinase MEKK2 (MAP3K2) activates the MEK5/ERK5 cell signaling pathway and may play an important role in tumor growth and metastasis. Thus, MEKK2 may…”
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Regioselective addition of Grignard reagents to N-acylpyrazinium salts: synthesis of substituted 1,2-dihydropyrazines and Δ5-2-oxopiperazines by St. Hilaire Valentine R, Hopkins, William E, Miller, Yenteeo S, Dandepally, Srinivasa R, Williams, Alfred L

“…The regioselective addition of Grignard reagents to mono- and disubstituted N-acylpyrazinium salts affording substituted 1,2-dihydropyrazines in modest to…”
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High Molecular Weight Polyglycerol-Based Multivalent Mannose Conjugates by Kizhakkedathu, Jayachandran N, Creagh, A. Louise, Shenoi, Rajesh A, Rossi, Nicholas A. A, Brooks, Donald E, Chan, Timmy, Lam, Jonathan, Dandepally, Srinivasa R, Haynes, Charles A

“…We report the synthesis and characterization of multivalent mannose conjugates based on high molecular weight hyperbranched polyglycerols (HPG). A range of…”
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Trifluoromethyl Analog of Verbenachalcone Promotes Neurite Outgrowth and Cell Proliferation of NeuroScreen-1 Cells by Yeyeodu, Susan, Gilyazova, Nailya, Huh, Eun Young, Dandepally, Srinivasa R, Oldham, Carla, Williams, Alfred, Ibeanu, Gordon

“…Past research has shown that natural products of plant and marine origins and their congeners enhance the actions of neuritogenic factors of the central…”
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p-methoxybenzyl (PMB) protection/deprotection approach toward the synthesis of 5-phenoxy-4-chloro-N-(aryl/alkyl) thiophene-2-sulfonamides by Williams, Alfred L, Dandepally, Srinivasa R, Kotturi, Sharadsrikar V

“…The synthesis of 17 phenoxy substituted 4-chloro-N-(aryl/alkyl)thiophene-2-sulfonamides using a PMB protection/deprotection strategy is described. Nucleophilic…”
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Regioselective addition of Grignard reagents to N -acylpyrazinium salts: synthesis of substituted 1,2-dihydropyrazines and Δ 5 -2-oxopiperazines by St Hilaire, Valentine R, Hopkins, William E, Miller, Yenteeo S, Dandepally, Srinivasa R, Williams, Alfred L

“…The regioselective addition of Grignard reagents to mono- and disubstituted -acylpyrazinium salts affording substituted 1,2-dihydropyrazines in modest to…”
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