Search Results - "Dance, Geoffrey S. C"
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Structural Phylogenetic Analysis of Activation-Induced Deaminase Function
Published in Journal of Immunology (01-07-2006)“…In mammals, activation-induced deaminase (AID) initiates somatic hypermutation (SHM) and class switch recombination (CSR) of Ig genes. SHM and CSR activities…”
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structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-2004)“…Activation-induced deaminase (AID) uses base deamination for class-switch recombination and somatic hypermutation and is related to the mammalian RNA-editing…”
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Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business
Published in Trends in genetics (01-04-2003)“…Alteration of mRNA sequence through base modification mRNA editing frequently generates protein diversity. Several proteins have been identified as being…”
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Two Proteins Essential for Apolipoprotein B mRNA Editing Are Expressed from a Single Gene through Alternative Splicing
Published in The Journal of biological chemistry (12-04-2002)“…Apolipoprotein B (apoB) mRNA editing involves site-specific deamination of cytidine to form uridine, resulting in the production of an in-frame stop codon…”
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Identification of the yeast cytidine deaminase CDD1 as an orphan C-->U RNA editase
Published in Nucleic acids research (15-04-2001)“…Yeast co-expressing rat APOBEC-1 and a fragment of human apolipoprotein B (apoB) mRNA assembled functional editosomes and deaminated C6666 to U in a mooring…”
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APOBEC-1 dependent cytidine to uridine editing of apolipoprotein B RNA in yeast
Published in Nucleic acids research (15-01-2000)“…Cytidine to uridine editing of apolipoprotein B (apoB) mRNA requires the cytidine deaminase APOBEC-1 as well as a tripartite sequence motif flanking a target…”
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