Search Results - "Danacikova, Sarka"
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Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit
Published in Frontiers in molecular neuroscience (06-04-2018)“…N-methyl-D-aspartate receptors (NMDARs), glutamate-gated ion channels, mediate signaling at the majority of excitatory synapses in the nervous system. Recent…”
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Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors
Published in Neuropharmacology (15-05-2021)“…N-methyl-d-aspartate receptors (NMDARs) play an essential role in regulating glutamatergic neurotransmission. Recently, pathogenic missense mutations were…”
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In vitro human cell culture models in a bench‐to‐bedside approach to epilepsy
Published in Epilepsia open (01-06-2024)“…Epilepsy is the most common chronic neurological disease, affecting nearly 1%–2% of the world's population. Current pharmacological treatment and regimen…”
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Sulforaphane Ameliorates Metabolic Changes Associated With Status Epilepticus in Immature Rats
Published in Frontiers in cellular neuroscience (15-03-2022)“…Status epilepticus (SE) is a common paediatric emergency with the highest incidence in the neonatal period and is a well-known epileptogenic insult. As…”
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Serum biomarkers of hypoxic-ischemic brain injury
Published in Physiological research (31-12-2023)“…Brain injury is a multifaceted condition arising from nonspecific damage to nervous tissue. The resulting cognitive developmental impairments reverberate…”
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