Search Results - "Dana, Reza"
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Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases
Published in The Journal of immunology (1950) (01-12-2019)“…Regulatory T cells (Tregs) play a central role in the induction and maintenance of immune homeostasis and self-tolerance. Tregs constantly express the…”
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Estimated Prevalence and Incidence of Dry Eye Disease Based on Coding Analysis of a Large, All-age United States Health Care System
Published in American journal of ophthalmology (01-06-2019)“…To assess overall prevalence, annual prevalence, and incidence of dry eye disease (DED) in a large, representative population in the United States. Prevalence…”
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When Clarity Is Crucial: Regulating Ocular Surface Immunity
Published in Trends in immunology (01-04-2018)“…The ocular surface is a unique mucosal immune compartment in which anatomical, physiological, and immunological features act in concert to foster a…”
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Subtarsal Fibrosis Is Associated With Ocular Surface Epitheliopathy in Graft-Versus-Host Disease
Published in American journal of ophthalmology (01-05-2018)“…To evaluate occurrence of subtarsal fibrosis in patients with graft-vs-host disease (GVHD) and to determine its association with ocular surface epitheliopathy…”
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Pathological conversion of regulatory T cells is associated with loss of allotolerance
Published in Scientific reports (04-05-2018)“…CD4 + CD25 + Foxp3 + Regulatory T cells (Tregs) play a critical role in immune tolerance. The plasticity and functional adaptability of Tregs in an…”
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Alloimmunity and Tolerance in Corneal Transplantation
Published in The Journal of immunology (1950) (15-05-2016)“…Corneal transplantation is one of the most prevalent and successful forms of solid tissue transplantation. Despite favorable outcomes, immune-mediated graft…”
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Patient-Reported Burden of Dry Eye Disease in the United States: Results of an Online Cross-Sectional Survey
Published in American journal of ophthalmology (01-08-2020)“…To evaluate functional vision, general health status, and work productivity in individuals with and without dry eye disease (DED). Cross-sectional study…”
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Therapeutic approaches for induction of tolerance and immune quiescence in corneal allotransplantation
Published in Cellular and molecular life sciences : CMLS (01-05-2018)“…The cornea is the most commonly transplanted tissue in the body. Corneal grafts in low-risk recipients enjoy high success rates, yet over 50% of high-risk…”
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Retinal microglia initiate neuroinflammation in ocular autoimmunity
Published in Proceedings of the National Academy of Sciences - PNAS (14-05-2019)“…Autoimmune uveitis is a sight-threatening ocular inflammatory condition in which the retina and uveal tissues become a target of autoreactive immune cells…”
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Defining Dry Eye from a Clinical Perspective
Published in International journal of molecular sciences (04-12-2020)“…Over the past decades, the number of patients with dry eye disease (DED) has increased dramatically. The incidence of DED is higher in Asia than in Europe and…”
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Sutureless repair of corneal injuries using naturally derived bioadhesive hydrogels
Published in Science advances (01-03-2019)“…Corneal injuries are common causes of visual impairment worldwide. Accordingly, there is an unmet need for transparent biomaterials that have high adhesion,…”
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IFN-γ-Expressing Th17 Cells Are Required for Development of Severe Ocular Surface Autoimmunity
Published in The Journal of immunology (1950) (01-08-2017)“…Th17 cells are critical effectors mediating the ocular surface autoimmunity in dry eye disease (DED). Increased IFN-γ has also been implicated in DED; however,…”
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13
Reprogrammable Graphene-based Metasurface Mirror with Adaptive Focal Point for THz Imaging
Published in Scientific reports (27-02-2019)“…Recent emergence of metasurfaces has enabled the development of ultra-thin flat optical components through different wavefront shaping techniques at various…”
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Impact of Dry Eye Syndrome on Vision-Related Quality of Life
Published in American journal of ophthalmology (01-03-2007)“…Purpose To evaluate the impact of dry eye syndrome (DES) on vision-associated quality of life. Design Cross-sectional study. Methods We identified 450…”
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Corneal Epithelial Immune Dendritic Cell Alterations in Subtypes of Dry Eye Disease: A Pilot In Vivo Confocal Microscopic Study
Published in Investigative ophthalmology & visual science (01-11-2015)“…To evaluate density and morphology of corneal epithelial immune dendritic cells (DCs) in different subtypes of dry eye disease (DED) using in vivo confocal…”
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Reduced Efficacy of Low-dose Topical Steroids in Dry Eye Disease Associated With Graft-versus-Host Disease
Published in American journal of ophthalmology (01-06-2018)“…To compare the response of dry eye disease (DED) to treatment with topical steroid in patients with and without graft-vs-host disease (GVHD). Post hoc analysis…”
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Cornea‐Derived Mesenchymal Stromal Cells Therapeutically Modulate Macrophage Immunophenotype and Angiogenic Function
Published in Stem cells (Dayton, Ohio) (01-05-2018)“…Macrophages are crucial drivers of inflammatory corneal neovascularization and thus are potential targets for immunomodulatory therapies. We hypothesized that…”
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Determinants of Ocular Pain Severity in Patients with Dry Eye Disease
Published in American journal of ophthalmology (01-07-2017)“…Abstract Purpose To quantify the severity of ocular pain in patients with dry eye disease (DED) and evaluate factors associated with pain severity. Design…”
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Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency
Published in Cornea (01-03-2019)“…PURPOSE:Despite extensive knowledge gained over the last 3 decades regarding limbal stem cell deficiency (LSCD), the disease is not clearly defined, and there…”
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Effects of Corneal Nerve Density on the Response to Treatment in Dry Eye Disease
Published in Ophthalmology (Rochester, Minn.) (01-04-2015)“…Purpose To evaluate whether levels of corneal subbasal nerve fiber length (SNFL) in dry eye disease (DED) could prognosticate the level of improvement in signs…”
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