Search Results - "Dan J. Siskind"
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Metformin for Clozapine Associated Obesity: A Systematic Review and Meta-Analysis
Published in PloS one (15-06-2016)“…Although clozapine is the gold-standard for treatment refractory schizophrenia, it has the worst metabolic profile of all antipsychotics. This is partly…”
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Augmentation strategies for clozapine refractory schizophrenia: A systematic review and meta-analysis
Published in Australian & New Zealand Journal of Psychiatry (01-08-2018)“…Background: Although clozapine is the most effective medication for treatment refractory schizophrenia, only 40% of people will meet response criteria. We…”
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Mental health implications for older adults after natural disasters--a systematic review and meta-analysis
Published in International psychogeriatrics (01-01-2016)“…Natural disasters affect the health and well-being of adults throughout the world. There is some debate in the literature as to whether older persons have…”
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The Mental Health of Older Persons After Human-Induced Disasters: A Systematic Review and Meta-Analysis of Epidemiological Data
Published in The American journal of geriatric psychiatry (01-05-2016)“…Background Older people are increasingly “in harm's way” following human-induced disasters (HIDs). There is debate in the literature as to the relative impact…”
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Clozapine-Encapsulated Binary Mixed Micelles in Thermosensitive Sol-Gels for Intranasal Administration
Published in Gels (05-01-2022)“…(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers…”
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Patterns of antipsychotic medication use in Australia 2002-2007
Published in Australian and New Zealand journal of psychiatry (01-04-2010)“…Objective: Atypical antipsychotic medications that are primarily used to treat schizophrenia and bipolar disorder cost the Pharmaceutical Benefits Scheme (PBS)…”
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A systematic review and meta‐analysis of the association between poor oral health and substance abuse
Published in Addiction (Abingdon, England) (01-05-2017)“…Background and aims Substance use disorders are associated commonly with comorbid physical illness. There are fewer data on dental disease in these conditions,…”
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Elevated clozapine levels associated with infection: A systematic review
Published in Schizophrenia research (01-02-2018)“…Abstract Clozapine is the most effective anti-psychotic medication for treatment refractory schizophrenia. A growing number of case reports have linked…”
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Clozapine shared care: mental health services and GPs working together for better outcomes for people with schizophrenia
Published in Medical journal of Australia (02-10-2022)Get full text
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Clozapine Efficacy and Adverse Drug Reactions Among a Nationwide Study of 1021 Australians Prescribed Clozapine: The ClozaGene Study
Published in Schizophrenia bulletin (07-05-2024)“…The ClozaGene Study is a nationwide cohort of adults who have been treated with clozapine. While clozapine is indicated in the management of…”
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Treatment of clozapine‐associated obesity and diabetes with exenatide in adults with schizophrenia: A randomized controlled trial (CODEX)
Published in Diabetes, obesity & metabolism (01-04-2018)“…Clozapine causes obesity and type 2 diabetes (T2DM). Glucagon‐like peptide‐1 (GLP‐1) receptor agonists (e.g. exenatide) can counter clozapine‐associated GLP‐1…”
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Nose-to-brain delivery of antipsychotics using nanotechnology: a review
Published in Expert opinion on drug delivery (02-06-2020)“…Orally-administered antipsychotics are effective in the management of psychosis-related disorders although generation-specific adverse drug reactions (ADRs)…”
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A systematic review and meta-analysis of the association between clozapine and norclozapine serum levels and peripheral adverse drug reactions
Published in Psychopharmacology (01-03-2021)“…Rationale Clozapine is the most effective antipsychotic for treatment-refractory schizophrenia for reducing positive psychotic symptoms. It is associated with…”
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Colorectal, cervical and prostate cancer screening in Australians with severe mental illness: Retrospective nation-wide cohort study
Published in Australian and New Zealand journal of psychiatry (01-06-2019)“…Objective: People with severe mental illness have similar cancer incidence, but higher mortality than the general population. Participation in cancer screening…”
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Pharmacological interventions for smoking cessation among people with schizophrenia spectrum disorders: a systematic review, meta-analysis, and network meta-analysis
Published in The Lancet. Psychiatry (01-09-2020)“…People with schizophrenia have higher rates of smoking than the general population, and lower quit rates. Several randomised controlled trials have…”
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Frequency and quality of mental health treatment for affective and anxiety disorders among Australian adults
Published in Medical journal of Australia (02-03-2015)“…Objectives: To describe the frequency, type and quality of mental health treatment among Australian adults with past‐year affective and/or anxiety disorders…”
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Fabrication and Characterization of Clozapine Nanoemulsion Sol–Gel for Intranasal Administration
Published in Molecular pharmaceutics (07-11-2022)“…Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia. However, it causes many adverse drug reactions (ADRs), which lead to poor…”
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Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
Published in Australian and New Zealand journal of psychiatry (01-11-2023)“…Objective: The Australian Genetics of Bipolar Disorder Study is a nation-wide cohort of adults living with bipolar disorder. The study aims to detect the…”
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Anxiolytic, hypnotic and sedative medication use in Australia
Published in Pharmacoepidemiology and drug safety (01-03-2010)“…Purpose New sedative drugs have been marketed in Australia in the last few years. We examined the trends in the prescribing of subsidised anxiolytic, hypnotic…”
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