Search Results - "Dan, Yee Shan"
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Key role for inflammation-related signaling in the pathogenesis of myopia based on evidence from proteomics analysis
Published in Scientific reports (08-10-2024)“…The mechanisms underlying myopia pathogenesis are not well understood. Using publicly-available human and animal datasets, we expound on the roles of known,…”
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Biomechanical changes occur in myopic choroidal stroma and mirror those in the adjacent sclera
Published in Communications engineering (09-10-2024)“…Retina-derived growth signals relayed from the choroid to the sclera cause remodeling of the extracellular scleral matrix, resulting in myopic ocular…”
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Quantitative assessment of the choroidal vasculature in myopic macular degeneration with optical coherence tomographic angiography
Published in Frontiers in ophthalmology (2023)“…To assess and compare choroidal morphometric vascular parameters, using optical coherence tomographic angiography (OCTA), in highly myopic adults with and…”
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Multimodal Imaging-Based Phenotyping of a Singaporean Hospital-Based Cohort of High Myopia Patients
Published in Frontiers in medicine (04-01-2022)“…To assess the effect of axial length (AL) on the prevalence of pathologic myopia (PM) and associated myopic features in a Singaporean hospital-based cohort of…”
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Biomechanical properties of the myopic choroid
Published in The Journal of the Acoustical Society of America (01-10-2023)“…Retina-derived growth signals relayed from the choroid to the sclera cause remodeling of the extracellular matrix, resulting in myopic ocular elongation…”
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Ultrasound Assessment of Gaze-induced Posterior Eyewall Deformation in Highly Myopic Eyes
Published in Investigative ophthalmology & visual science (25-10-2023)“…To establish a quantitative metric of posterior eyewall deformability in different directions of gaze in highly myopic eyes with and without posterior…”
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Automated in vivo detection and localization of posterior staphyloma in ultrasound b-modes
Published in The Journal of the Acoustical Society of America (01-10-2021)“…In high and pathologic myopia eyes, staphyloma, an outpouching of the eyewall, is associated with risks of permanent vision loss. Automated detection of…”
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Automated Classification and Detection of Staphyloma with Ultrasound Images in Pathologic Myopia Eyes
Published in Ultrasound in medicine & biology (01-12-2022)“…The aim of this study was to develop an eyewall curvature- and axial length (AxL)–based algorithm to automate detection (clinician-free) of staphyloma ridge…”
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Choroidal Thickness in Early Postnatal Guinea Pigs Predicts Subsequent Naturally Occurring and Form-Deprivation Myopia
Published in Investigative ophthalmology & visual science (14-10-2022)“…PurposeTo identify choroidal characteristics associated with susceptibility to development of naturally occurring and experimentally induced myopia. MethodsWe…”
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Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration
Published in Investigative ophthalmology & visual science (01-06-2021)“…PurposeThe purpose of this study was to assess whether the tractional elements of pathologic myopia (PM; e.g. myopic traction maculopathy [MTM], posterior…”
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Macular Sensitivity and Capillary Perfusion in Highly Myopic Eyes with Myopic Macular Degeneration
Published in Retina (Philadelphia, Pa.) (18-10-2021)Get full text
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MACULAR SENSITIVITY AND CAPILLARY PERFUSION IN HIGHLY MYOPIC EYES WITH MYOPIC MACULAR DEGENERATION
Published in Retina (Philadelphia, Pa.) (01-03-2022)“…To evaluate the interrelationship between macular sensitivity and retinal perfusion density (PD) in eyes with myopic macular degeneration (MMD). One hundred…”
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