Search Results - "Dams, Geert"
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Targeting ferroptosis protects against experimental (multi)organ dysfunction and death
Published in Nature communications (24-02-2022)“…The most common cause of death in the intensive care unit (ICU) is the development of multiorgan dysfunction syndrome (MODS). Besides life-supporting…”
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Metformin and Canagliflozin Are Equally Renoprotective in Diabetic Kidney Disease but Have No Synergistic Effect
Published in International journal of molecular sciences (20-05-2023)“…Diabetic Kidney Disease (DKD) is a major microvascular complication for diabetic patients and is the most common cause of chronic kidney disease (CKD) and…”
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Osteocytic Sclerostin Expression as an Indicator of Altered Bone Turnover
Published in Nutrients (2023)“…Renal osteodystrophy (ROD) is a complex and serious complication of chronic kidney disease (CKD), a major global health problem caused by loss of renal…”
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Disturbances in Bone Largely Predict Aortic Calcification in an Alternative Rat Model Developed to Study Both Vascular and Bone Pathology in Chronic Kidney Disease
Published in Journal of bone and mineral research (01-12-2015)“…ABSTRACT Because current rat models used to study chronic kidney disease (CKD)‐related vascular calcification show consistent but excessive vascular…”
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A magnesium based phosphate binder reduces vascular calcification without affecting bone in chronic renal failure rats
Published in PloS one (17-09-2014)“…The alternative phosphate binder calcium acetate/magnesium carbonate (CaMg) effectively reduces hyperphosphatemia, the most important inducer of vascular…”
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Differences in gastrointestinal calcium absorption after the ingestion of calcium-free phosphate binders
Published in American journal of physiology. Renal physiology (01-01-2014)“…Both calcium-containing and noncalcium-containing phosphate binders can increase gastrointestinal calcium absorption. Previously, we observed that lanthanum…”
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Useful biochemical markers for diagnosing renal osteodystrophy in predialysis end-stage renal failure patients
Published in American journal of kidney diseases (01-05-2003)“…Various biochemical markers have been evaluated in dialysis patients for the diagnosis of renal osteodystrophy (ROD). However, their value in predialysis…”
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Role of dietary phosphorus and degree of uremia in the development of renal bone disease in rats
Published in Renal failure (2007)“…The remnant kidney rat model has been extensively used for the evaluation of bone changes due to uremia. The present study aimed to assess the effect of the…”
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Can Intestinal Phosphate Binding or Inhibition of Hydroxyapatite Growth in the Vascular Wall Halt the Progression of Established Aortic Calcification in Chronic Kidney Disease?
Published in Calcified tissue international (01-11-2016)“…Vascular calcification significantly contributes to mortality in chronic kidney disease (CKD) patients. Sevelamer and pyrophosphate (PPi) have proven to be…”
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Adequate phosphate binding with lanthanum carbonate attenuates arterial calcification in chronic renal failure rats
Published in Nephrology, dialysis, transplantation (01-06-2009)“…Background. Hyperphosphataemia is a risk factor for arterial calcification contributing to the high cardiovascular mortality in patients with chronic kidney…”
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High-Resolution X-Ray Microtomography Is a Sensitive Method to Detect Vascular Calcification in Living Rats With Chronic Renal Failure
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2006)“…OBJECTIVE—Chronic renal failure (CRF) is associated with a 10- to 20-fold increase in cardiovascular risk. Vascular calcification is a prominent feature of…”
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Does the phosphate binder lanthanum carbonate affect bone in rats with chronic renal failure?
Published in Journal of the American Society of Nephrology (01-08-2004)“…Adequate control of phosphate levels remains an important issue in patients with chronic renal failure (CRF). Lanthanum carbonate has been proposed as a new…”
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Spectrum of renal bone disease in end‐stage renal failure patients not yet on dialysis
Published in Nephrology, dialysis, transplantation (01-06-2003)“…Background. During the last few years the spectrum of renal osteodystrophy (ROD) in dialysis patients has been studied thoroughly and the prevalence of the…”
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Time-evolution and reversibility of strontium-induced osteomalacia in chronic renal failure rats
Published in Kidney international (01-03-2005)“…Time-evolution and reversibility of strontium-induced osteomalacia in chronic renal failure rats. Patients with impaired renal function can accumulate…”
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Dose-dependent effects of strontium on bone of chronic renal failure rats
Published in Kidney international (01-03-2003)“…Dose-dependent effects of strontium on bone of chronic renal failure rats. We previously reported on increased bone strontium (Sr) levels in dialysis patients…”
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Development and reversibility of impaired mineralization associated with lanthanum carbonate treatment in chronic renal failure rats
Published in Bone (New York, N.Y.) (01-06-2006)“…We have previously shown that administration of the new phosphate binder lanthanum (La) carbonate at high doses during 12 weeks induces a mineralization defect…”
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Effects of efficient phosphate binding on bone in chronic renal failure rats
Published in Renal failure (01-01-2005)“…We recently reported that administration of high doses of lanthanum carbonate (1000 mg/kg/day) to chronic renal failure (CRF) rats can result in a…”
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Strontium incorporates at sites critical for bone mineralization in rats with renal failure
Published in X-ray spectrometry (01-01-2007)“…We previously demonstrated the development of a mineralization defect during strontium administration and its reversibility after withdrawal in rats with…”
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