Search Results - "Damme, Jo van"

The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer by Hannelien, Verbeke, Karel, Geboes, Jo, Van Damme, Sofie, Struyf

“…Chronic inflammation may increase the risk to develop cancer, for instance esophagitis or gastritis may lead to development of esophageal or gastric cancer,…”
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Chemokine-Induced Macrophage Polarization in Inflammatory Conditions by Ruytinx, Pieter, Proost, Paul, Van Damme, Jo, Struyf, Sofie

“…Macrophages represent a heterogeneous cell population and are known to display a remarkable plasticity. In response to distinct micro-environmental stimuli,…”
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Isotypic neutralizing antibodies against mouse GCP-2/CXCL6 inhibit melanoma growth and metastasis by Verbeke, Hannelien, Struyf, Sofie, Berghmans, Nele, Van Coillie, Els, Opdenakker, Ghislain, Uyttenhove, Catherine, Van Snick, Jacques, Van Damme, Jo

“…Abstract The chemokine granulocyte chemotactic protein (GCP)-2/CXCL6 promotes tumor growth as angiogenesis inducer and neutrophil chemoattractant. The…”
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Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis by Opdenakker, Ghislain, Nelissen, Inge, Van Damme, Jo

“…Multiple sclerosis (MS) is a demyelinating disease of the CNS of unknown cause. Pathogenetic mechanisms, such as chemotaxis, subsequent activation of…”
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TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis by Loos, Tamara, Dekeyzer, Lies, Struyf, Sofie, Schutyser, Evemie, Gijsbers, Klara, Gouwy, Mieke, Fraeyman, Annelies, Put, Willy, Ronsse, Isabelle, Grillet, Bernard, Opdenakker, Ghislain, Damme, Jo Van, Proost, Paul

“…CXC chemokines are potent attractants of neutrophil granulocytes, T cells or natural killer cells. Toll-like receptors (TLR) recognize microbial components and…”
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Remnant Epitopes Generating Autoimmunity: From Model to Useful Paradigm by Opdenakker, Ghislain, Abu El-Asrar, Ahmed, Van Damme, Jo

“…Autoimmune diseases are defined as pathologies of adaptive immunity by the presence of autoantibodies or MHC-restricted autoantigen-reactive T cells. Because…”
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Immunomodulation as Rescue for Chronic Atonic Skin Wounds by Opdenakker, Ghislain, Van Damme, Jo, Vranckx, Jan Jeroen

“…Chronic skin wounds, caused by arterial or venous insufficiency or by physical pressure, constitute an increasing medical problem as populations age. Whereas…”
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The turning away of serum amyloid A biological activities and receptor usage by Abouelasrar Salama, Sara, Gouwy, Mieke, Van Damme, Jo, Struyf, Sofie

“…Commercial recombinant SAA variants contaminated with bacterial products do not reflect the inherent biological characteristics of endogenous SAA. In reliable…”
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Microbiomic and Posttranslational Modifications as Preludes to Autoimmune Diseases by Opdenakker, Ghislain, Proost, Paul, Van Damme, Jo

“…Diagnosis and treatment of autoimmunity has mainly relied on adaptive immunity. Infection and inflammation induce cytokines and chemokines and activate myeloid…”
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Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults by De Buck, Mieke, Gouwy, Mieke, Wang, Ji Ming, Van Snick, Jacques, Opdenakker, Ghislain, Struyf, Sofie, Van Damme, Jo

“…Serum amyloid A (SAA) is, like C-reactive protein (CRP), an acute phase protein and can be used as a diagnostic, prognostic or therapy follow-up marker for…”
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The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer by Vandercappellen, Jo, Van Damme, Jo, Struyf, Sofie

“…Abstract Chemokines are chemotactic cytokines which recruit leukocytes to inflammatory sites. They also affect tumor development and metastasis by acting as…”
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CD26/dipeptidylpeptidase IV—chemokine interactions: double‐edged regulation of inflammation and tumor biology by Mortier, Anneleen, Gouwy, Mieke, Van Damme, Jo, Proost, Paul, Struyf, Sofie

“…Review of how chemokine processing by CD26/DPP IV regulates leukocyte trafficking. Post‐translational modification of chemokines is an essential regulatory…”
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The countercurrent principle in invasion and metastasis of cancer cells. Recent insights on the roles of chemokines by Opdenakker, Ghislain, Van Damme, Jo

“…Chemokine production by cancer cells constitutes a duality. Leukocyte recruitment under the pressure of chemokines may be beneficial for the host or for the…”
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Regulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26 by Metzemaekers, Mieke, Van Damme, Jo, Mortier, Anneleen, Proost, Paul

“…Chemokines are small, chemotactic proteins that play a crucial role in leukocyte migration and are, therefore, essential for proper functioning of the immune…”
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On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation by Vandooren, Jennifer, Van Damme, Jo, Opdenakker, Ghislain

“…The blood-brain barrier (BBB) is a specific structure that is composed of two basement membranes (BMs) and that contributes to the control of…”
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The expression and role of CXC chemokines in colorectal cancer by Verbeke, Hannelien, Struyf, Sofie, Laureys, Geneviève, Van Damme, Jo

“…Abstract Cancer is a life-threatening disease world-wide and colorectal cancer is the second common cause of cancer mortality. The interaction between tumor…”
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Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-γ in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids by Proost, Paul, Verpoest, Sara, De Borne, Kirsten Van, Schutyser, Evemie, Struyf, Sofie, Put, Willy, Ronsse, Isabelle, Grillet, Bernard, Opdenakker, Ghislain, Damme, Jo Van

“…The synovial cavity constitutes the ideal stage to study the interplay between microbial Toll‐like receptor (TLR) ligands and cytokines. Infiltrated leukocytes…”
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The Role of Post-Translational Modifications of Chemokines by CD26 in Cancer by De Zutter, Alexandra, Van Damme, Jo, Struyf, Sofie

“…Chemokines are a large family of small chemotactic cytokines that fulfill a central function in cancer. Both tumor-promoting and -impeding roles have been…”
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Antibodies as tools in cytokine discovery and usage for diagnosis and therapy of inflammatory diseases by Van Damme, Jo, Opdenakker, Ghislain, Van Damme, Sam, Struyf, Sofie

“…Polyclonal antisera from patients have been at the basis of the description of autoimmune diseases and today monoclonal antibodies are widely used in the…”
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Chemoattractants and cytokines in primary ciliary dyskinesia and cystic fibrosis: key players in chronic respiratory diseases by Cockx, Maaike, Gouwy, Mieke, Van Damme, Jo, Struyf, Sofie

“…Patients with primary ciliary dyskinesia (PCD) and cystic fibrosis (CF), two inherited disorders, suffer from recurrent airway infections characterized by…”
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