Search Results - "Damle, Aarti"

Dissecting the Genetic Complexity of the Association between Human Leukocyte Antigens and Rheumatoid Arthritis by Jawaheer, Damini, Li, Wentian, Graham, Robert R., Chen, Wei, Damle, Aarti, Xiao, Xiangli, Monteiro, Joanita, Khalili, Houman, Lee, Annette, Lundsten, Robert, Begovich, Ann, Bugawan, Teodorica, Erlich, Henry, Elder, James T., Criswell, Lindsey A., Seldin, Michael F., Amos, Christopher I., Behrens, Timothy W., Gregersen, Peter K.

“…Rheumatoid arthritis (RA) is an inflammatory disease with a complex genetic component. An association between RA and the human leukocyte antigen (HLA) complex…”
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Transcription Profiles of Rheumatoid Arthritis Patients Reveal Genes Characterizing Different Response to Anti-TNF Therapy by Batliwalla, Franak, Assistant Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Gregersen, Peter, Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Allaire, Normand, Scientist, BiogenIdec, Drug Discovery, Cambridge, NY, Li, Wentian, Assistant Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Perrin, Steve, Associate Director, BiogenIdec, Drug Discovery, Cambridge, MA, Kern, Marlena, Research Associate, Feinstein Institute for Medical Research, Manhasset, NY, Damle, Aarti, Research Associate, Feinstein Institute for Medical Research, Manhasset, NY, Carulli, John, Principal Scientist, BiogenIdec, Drug Discovery, Cambridge, MA, Bienkowska, Jadwiga, Principal Scientist, Biogenidec, Drug Discovery, Cambridge, MA

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Genome-Wide SNP Scan Identifies Polymorphisms Associated with Differential Response to Anti-TNF Treatment Among Rheumatoid Arthritis Patients in the ABCoN Cohort by Carulli, John, Principal Scientist, BiogenIdec, Cambridge, MA, Batliwalla, Franak, Assistant Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Liu, Chunyu, Scientist, BiogenIdec, Drug Discovery, Cambridge, MA, Damle, Aarti, Assistant Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Bienkowska, Jadwiga, Principal Scientist, Biogenidec, Drug Discovery, Cambridge, MA, Lee, Annette, Assistant Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Li, Wentian, Assistant Investigator, Feinstein Institute for Medical Research, Manhasset, NY, Gregersen, Peter, Investigator, Feinstein Institute for Medical Research, Manhasset, NY

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Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis by Liu, Chunyu, Batliwalla, Franak, Li, Wentian, Lee, Annette, Roubenoff, Ronenn, Beckman, Evan, Khalili, Houman, Damle, Aarti, Kern, Marlena, Furie, Richard, Dupuis, Josée, Plenge, Robert M, Coenen, Marieke J H, Behrens, Timothy W, Carulli, John P, Gregersen, Peter K

“…The prediction of response (or non-response) to anti-TNF treatment for rheumatoid arthritis (RA) is a pressing clinical problem. We conducted a genome-wide…”
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Screening the genome for rheumatoid arthritis susceptibility genes: A replication study and combined analysis of 512 multicase families by Jawaheer, Damini, Seldin, Michael F., Amos, Christopher I., Chen, Wei V., Shigeta, Russell, Etzel, Carol, Damle, Aarti, Xiao, Xiangli, Chen, Dong, Lum, Raymond F., Monteiro, Joanita, Kern, Marlene, Criswell, Lindsey A., Albani, Salvatore, Nelson, J. Lee, Clegg, Daniel O., Pope, Richard, Schroeder, Harry W., Bridges, S. Louis, Pisetsky, David S., Ward, Ryk, Kastner, Daniel L., Wilder, Ronald L., Pincus, Theodore, Callahan, Leigh F., Flemming, Donald, Wener, Mark H., Gregersen, Peter K.

“…Objective A number of non‐HLA loci that have shown evidence (P < 0.05) for linkage with rheumatoid arthritis (RA) have been previously identified. The present…”
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Gene Set Enrichment Analysis of Ki-67high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease by Yan, Xiao J., Kalenscher, Daniel, Boyle, Erin, Yancopoulos, Sophia, Damle, Rajendra N, Damle, Aarti, Khalili, Houman, Lee, Annette, Li, Wentian, Dozmorov, Igor, Kaufman, Matthew, Gregersen, Peter, Allen, Steven L., Kolitz, Jonathan E., Rai, Kanti R., Chiorazzi, Nicholas

“…Abstract 2833 In chronic lymphocytic leukemia (CLL), clonally expanded CD5+ B lymphocytes eventually overwhelm healthy immune cells, hindering normal immune…”
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Gene expression patterns in peripheral blood cells associated with radiographic severity in African Americans with early rheumatoid arthritis by Reynolds, Richard J., Cui, Xiangqin, Vaughan, Laura K., Redden, David T., Causey, Zenoria, Perkins, Elizabeth, Shah, Tishi, Hughes, Laura B., Damle, Aarti, Kern, Marlena, Gregersen, Peter K., Johnson, Martin R., Bridges, S. Louis

“…Gene expression profiling may be used to stratify patients by disease severity to test the hypothesis that variable disease outcome has a genetic component. In…”
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Combining Expression of Hypervariably Expressed Genes with IGHV Mutation Status Is a More Robust Prognostic Indicator Than Mutation Status Alone in Chronic Lymphocytic Leukemia by Yan, Xiao J., Dozmorov, Igor, Ivana, Ivanovic, Yancopoulos, Sophia, Kalenscher, Daniel, Boyle, Erin, Damle, Aarti, Damle, Rajendra N, Chu, Charles C., Khalili, Houman, Lee, Annette, Li, Wentian, Gregersen, Peter, Sison, Cristina, Lesser, Martin L, Kaufman, Matthew, Allen, Steven L., Kolitz, Jonathan E., Rai, Kanti R., Chiorazzi, Nicholas

“…Abstract 1774 Chronic Lymphocytic Leukemia (CLL) follows a variable, difficult to predict course. Biomarkers (IGHV mutations, CD38 and ZAP-70) have improved…”
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