Search Results - "Damijan Miklavčič"

Membrane Electroporation and Electropermeabilization: Mechanisms and Models by Kotnik, Tadej, Rems, Lea, Tarek, Mounir, Miklav i, Damijan

“…Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient increase in their plasma membrane permeability, allowing…”
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Cell death due to electroporation – A review by Batista Napotnik, Tina, Polajžer, Tamara, Miklavčič, Damijan

“…•Cell death mechanisms after electroporation are reviewed.•Cells after electroporation die through necrosis, apoptosis, necroptosis and pyroptosis.•Multiple…”
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In vitro electroporation detection methods – An overview by Batista Napotnik, Tina, Miklavčič, Damijan

“…Exposing cells to an electric field leads to electroporation of the cell membrane which has already been explored and used in a number of applications in…”
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Electroporation-based applications in biotechnology by Kotnik, Tadej, Frey, Wolfgang, Sack, Martin, Haberl Meglič, Saša, Peterka, Matjaž, Miklavčič, Damijan

“…Highlights • We review four promising biotechnological applications of electroporation. • Reversible electroporation is an efficient method for genetic…”
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Scratching the electrode surface: Insights into a high-voltage pulsed-field application from in vitro & in silico studies in indifferent fluid by Mahnič-Kalamiza, Samo, Miklavčič, Damijan

“…Electroporation is employed ever more frequently and broadly to deliver energy to tissues and liquid media in various applications, thus answering questions on…”
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Muscle contractions and pain sensation accompanying high-frequency electroporation pulses by Cvetkoska, Aleksandra, Maček-Lebar, Alenka, Trdina, Peter, Miklavčič, Damijan, Reberšek, Matej

“…To minimize neuromuscular electrical stimulation during electroporation-based treatments, the replacement of long monophasic pulses with bursts of biphasic…”
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Electroporation-based technologies for medicine: principles, applications, and challenges by Yarmush, Martin L, Golberg, Alexander, Serša, Gregor, Kotnik, Tadej, Miklavčič, Damijan

“…When high-amplitude, short-duration pulsed electric fields are applied to cells and tissues, the permeability of the cell membranes and tissue is increased…”
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Effect of the cholesterol on electroporation of planar lipid bilayer by Kramar, Peter, Miklavčič, Damijan

“…•Planar lipid bilayers were prepared from POPC lipids with addition of cholesterol.•Capacitance, breakdown voltage and lifetime of planar lipid bilayers were…”
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Electroporation in Food Processing and Biorefinery by Mahnič-Kalamiza, Samo, Vorobiev, Eugène, Miklavčič, Damijan

“…Electroporation is a method of treatment of plant tissue that due to its nonthermal nature enables preservation of the natural quality, colour and vitamin…”
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Development of adaptive resistance to electric pulsed field treatment in CHO cell line in vitro by Polajžer, Tamara, Miklavčič, Damijan

“…Pulsed electric field treatment has increased over the last few decades with successful translation from in vitro studies into different medical treatments…”
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Network for Development of Electroporation-Based Technologies and Treatments: COST TD1104 by Miklavcic, Damijan

“…Exposure of biological cells to a sufficiently strong external electric field results in increased permeability of cell membranes, referred to as…”
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Electroporation with nanosecond pulses and bleomycin or cisplatin results in efficient cell kill and low metal release from electrodes by Vižintin, Angelika, Marković, Stefan, Ščančar, Janez, Miklavčič, Damijan

“…•Nanopulses in combination with bleomycin or cisplatin successfully kill cells.•Nanopulses are comparably effective as 8 × 100 μs pulses in…”
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Dynamics of Cell Death Due to Electroporation Using Different Pulse Parameters as Revealed by Different Viability Assays by Peng, Wencheng, Polajžer, Tamara, Yao, Chenguo, Miklavčič, Damijan

“…The mechanisms of cell death due to electroporation are still not well understood. Recent studies suggest that cell death due to electroporation is not an…”
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Revisiting the role of pulsed electric fields in overcoming the barriers to in vivo gene electrotransfer by Sachdev, Shaurya, Potočnik, Tjaša, Rems, Lea, Miklavčič, Damijan

“…[Display omitted] Gene therapies are revolutionizing medicine by providing a way to cure hitherto incurable diseases. The scientific and technological advances…”
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High-Voltage Electrical Pulses in Oncology: Irreversible Electroporation, Electrochemotherapy, Gene Electrotransfer, Electrofusion, and Electroimmunotherapy by Geboers, Bart, Scheffer, Hester J, Graybill, Philip M, Ruarus, Alette H, Nieuwenhuizen, Sanne, Puijk, Robbert S, van den Tol, Petrousjka M, Davalos, Rafael V, Rubinsky, Boris, de Gruijl, Tanja D, Miklavčič, Damijan, Meijerink, Martijn R

“…This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical oncology to treat solid tumors with irreversible electroporation (IRE) and…”
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Quantification of cell membrane permeability induced by monopolar and high-frequency bipolar bursts of electrical pulses by Sweeney, Daniel C., Reberšek, Matej, Dermol, Janja, Rems, Lea, Miklavčič, Damijan, Davalos, Rafael V.

“…High-frequency bipolar electric pulses have been shown to mitigate undesirable muscle contraction during irreversible electroporation (IRE) therapy. Here, we…”
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Determination of the Impact of High-Intensity Pulsed Electromagnetic Fields on the Release of Damage-Associated Molecular Pattern Molecules by Kranjc, Matej, Polajžer, Tamara, Novickij, Vitalij, Miklavčič, Damijan

“…High-Intensity Pulsed Electromagnetic Fields (HI-PEMF) treatment is an emerging noninvasive and contactless alternative to conventional electroporation, since…”
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Mathematical Models Describing Chinese Hamster Ovary Cell Death Due to Electroporation In Vitro by Dermol, Janja, Miklavčič, Damijan

“…Electroporation is a phenomenon used in the treatment of tumors by electrochemotherapy, non-thermal ablation with irreversible electroporation, and gene…”
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Induced Transmembrane Voltage and Its Correlation with Electroporation-Mediated Molecular Transport by Kotnik, Tadej, Pucihar, Gorazd, Miklavčič, Damijan

“…Exposure of a cell to an electric field results in inducement of a voltage across its membrane (induced transmembrane voltage, ΔΨ m) and, for sufficiently…”
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Electrochemotherapy: from the drawing board into medical practice by Miklavčič, Damijan, Mali, Barbara, Kos, Bor, Heller, Richard, Serša, Gregor

“…Electrochemotherapy is a local treatment of cancer employing electric pulses to improve transmembrane transfer of cytotoxic drugs. In this paper we discuss…”
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