Search Results - "Damian, Raymond T."

Sm‐p80‐based schistosomiasis vaccine: double‐blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission‐blocking efficacy by Zhang, Weidong, Molehin, Adebayo J., Rojo, Juan U., Sudduth, Justin, Ganapathy, Pramodh K., Kim, Eunjee, Siddiqui, Arif J., Freeborn, Jasmin, Sennoune, Souad R., May, Jordan, Lazarus, Samra, Nguyen, Catherine, Redman, Whitni K., Ahmad, Gul, Torben, Workineh, Karmakar, Souvik, Le, Loc, Kottapalli, Kameswara R., Kottapalli, Pratibha, Wolf, Roman F., Papin, James F., Carey, David, Gray, Sean A., Bergthold, Jenn D., Damian, Raymond T., Mayer, Bryan T., Marks, Florian, Reed, Steven G., Carter, Darrick, Siddiqui, Afzal A.

“…Schistosomiasis is of public health importance to an estimated one billion people in 79 countries. A vaccine is urgently needed. Here, we report the results of…”
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Cross-species protection: Schistosoma mansoni Sm-p80 vaccine confers protection against Schistosoma haematobium in hamsters and baboons by Karmakar, Souvik, Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Alam, Mayeen U, Le, Loc, Damian, Raymond T, Wolf, Roman F, White, Gary L, Carey, David W, Carter, Darrick, Reed, Steven G, Siddiqui, Afzal A

“…Highlights • Sm-p80 vaccine originally developed for Schistosoma mansoni confers protection against Schistosoma haematobium. • Sm-p80 vaccine has a high…”
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Sm-p80—Based DNA Vaccine Provides Baboons with Levels of Protection against Schistosoma mansoni Infection Comparable to Those Achieved by the Irradiated Cercarial Vaccine by Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Noor, Zahid, Le, Loc, Damian, Raymond T., Wolf, Roman F., White, Gary L., Chavez-Suarez, Maria, Podesta, Ronald B., Kennedy, Ronald C., Siddiqui, Afzal A.

“…To date, no vaccine is available to prevent human schistosomiasis. We have targeted a protein of Schistosoma mansoni that plays an important role in the…”
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Altered Levels of Hypothalamic-Pituitary-Adrenocortical Axis Hormones in Baboons and Mice during the Course of Infection with Schistosoma mansoni by Morales-Montor, J., Newhouse, E., Mohamed, F., Baghdadi, A., Damian, Raymond T.

“…Baboons with primary or secondary exposure to Schistosoma mansoni were compared with each other over a 12-week infection period and with baseline values…”
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Preclinical Prophylactic Efficacy Testing of Sm-p80-Based Vaccine in a Nonhuman Primate Model of Schistosoma mansoni Infection and Immunoglobulin G and E Responses to Sm-p80 in Human Serum Samples From an Area Where Schistosomiasis Is Endemic by Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Ahrorov, Afzal, Damian, Raymond T., Wolf, Roman F., White, Gary L., Carey, David W., Mwinzi, Pauline N. M., Ganley-Leal, Lisa, Kennedy, Ronald C., Siddiqui, Afzal A.

“…The prophylactic efficacy of a schistosome antigen (Sm-p80) was tested in a nonhuman primate model, the baboon.Using a total of 28 baboons, different…”
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Use of an Sm-p80–Based Therapeutic Vaccine to Kill Established Adult Schistosome Parasites in Chronically Infected Baboons by Karmakar, Souvik, Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Alam, Mayeen U., Le, Loc, Damian, Raymond T., Wolf, Roman F., White, Gary L., Carey, David W., Carter, Darrick, Reed, Steven G., Siddiqui, Afzal A.

“…No vaccines are available for human use for any parasitic infections, including the helminthic disease schistosomiasis. Sm-p80, the large subunit of…”
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Cysteine Proteinase Inhibitors in Murine Cysticercosis by Baig, Salman, Damian, Raymond T, Morales-Montor, Jorge, Thazhath, Rupal, Ghaleb, Amr, Welch, Meredith, Talhouk, Jamil, White, Jr, A Clinton

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Longevity of Sm-p80-specific antibody responses following vaccination with Sm-p80 vaccine in mice and baboons and transplacental transfer of Sm-p80-specific antibodies in a baboon by Zhang, Weidong, Ahmad, Gul, Le, Loc, Rojo, Juan U, Karmakar, Souvik, Tillery, Kory A, Torben, Workineh, Damian, Raymond T, Wolf, Roman F, White, Gary L, Carey, David W, Carter, Darrick, Reed, Steven G, Siddiqui, Afzal A

“…Based on data obtained using vaccine efficacy studies in mice, hamsters, and baboons, the credentials of Sm-p80 as a first tier vaccine candidate for…”
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Schistosoma mansoni Heat Shock Protein 70 Elicits an Early Humoral Immune Response in S. mansoni Infected Baboons by Kanamura, Herminia Y, Hancock, Kathy, Rodrigues, Vanderlei, Damian, Raymond T

“…A study was undertaken to search for DNA recombinant Schistosoma mansoni proteins responsible for eliciting an antibody response from the host at a very early…”
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Protective and antifecundity effects of Sm-p80-based DNA vaccine formulation against Schistosoma mansoni in a nonhuman primate model by Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Damian, Raymond T, Wolf, Roman F, White, Gary L, Chavez-Suarez, Maria, Kennedy, Ronald C, Siddiqui, Afzal A

“…Abstract Schistosomiasis is an important parasitic disease for which there is no available vaccine. We have focused on a functionally important antigen of…”
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Experimental vaccines in animal models for schistosomiasis by Siddiqui, Afzal A, Ahmad, Gul, Damian, Raymond T, Kennedy, Ronald C

“…Considerable morbidity and mortality results from the affliction of an estimated 200 million people worldwide by several species of schistosomes; 779 million…”
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DICYEMA SHORTI N. SP. (PHYLUM DICYEMIDA) FROM OCTOPUS BURRYI (MOLLUSCA: CEPHALOPODA: OCTOPODIDAE) IN THE GULF OF MEXICO by Furuya, Hidetaka, Damian, Raymond T, Hochberg, F. G

“…Nematogens and vermiform embryos of a new species of Dicyema are described from an octopus collected off Veracruz, México. Dicyema shorti n. sp. is a small…”
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A 3 kDa peptide is involved in the chemoattraction in vitro of the male Schistosoma mansoni to the female by Ghaleb, Amr M., Atwood, James, Morales-Montor, Jorge, Damian, Raymond T.

“…In vitro experiments on adult Schistosoma mansoni worms have shown the existence of mutual attraction between males and females mediated by factor(s) released…”
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Protection from murine cysticercosis by immunization with a parasite cysteine protease by Baig, Salman, Damian, Raymond T., Morales-Montor, Jorge, Ghaleb, Amr, Baghdadi, Amjed, White, A. Clinton

“…Central nervous system infection by Taenia solium cysts causes neurocysticercosis, a common neurological infection in the Third World. We have previously…”
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Schistosoma mansoni: the effect of adrenalectomy on the murine model by Morales-Montor, Jorge, Mohamed, Fawzy, Damian, Raymond T.

“…Adrenal steroid hormones have been implicated, among others, as one of the most important host factors controlling the onset, establishment, and pathogenesis…”
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Schistosoma spp.: Isolation of microtubule associated proteins in the tegument and the definition of dynein light chains components by Githui, Elijah K., Damian, Raymond T., Aman, Rashid A., Ali, Mohamed A., Kamau, Joseph M.

“…Schistosomes are parasitic blood flukes that reside in human mesenteric veins or urinary bladder veins, depending on species of the parasite. The syncytial…”
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Schistosoma mansoni: Biochemical characterization of lactate transporters or similar proteins by Githui, Elijah K., Damian, Raymond T., Aman, Rashid A.

“…While in medium containing glucose, schistosomes exhibit homolactic fermentation. Accumulation of lactate acid in tissue fluid causes lowering of pH and a…”
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A novel cathepsin B active site motif is shared by helminth bloodfeeders by Baig, Salman, Damian, Raymond T, Peterson, David S

“…This study compared specific protein sequence motifs present within cathepsin B-like cysteine proteases from a number of helminth parasites. We have focused…”
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Expression of mRNA for interleukin-1β, interleukin-6, tumor necrosis factor-α and macrophage migration inhibitory factor in HPA-axis tissues in Schistosoma mansoni-infected baboons ( Papio cynocephalus) by Morales-Montor, Jorge, Mohamed, Fawzi, Baghdadi, Amjed, Baig, Salman, Hallal-Calleros, Claudia, Damian, Raymond T

“…Cytokines may regulate the function of the hypothalamic–pituitary–adrenal axis during schistosomiasis. This possibility was investigated in baboons…”
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Dicyema shorti n. sp. (Phylum Dicyemida) from Octopus burryi (Mollusca: Cephalopoda: Octopodidae) in the Gulf of Mexico by Furuya, Hidetaka, Damian, Raymond T., Hochberg, F. G.

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