Search Results - "Damgård Nielsen, Gunnar"

Re-evaluation of the WHO (2010) formaldehyde indoor air quality guideline for cancer risk assessment by Nielsen, Gunnar Damgård, Larsen, Søren Thor, Wolkoff, Peder

“…In 2010, the World Health Organization (WHO) established an indoor air quality guideline for short- and long-term exposures to formaldehyde (FA) of 0.1 mg/m 3…”
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Cancer effects of formaldehyde: a proposal for an indoor air guideline value by Nielsen, Gunnar Damgård, Wolkoff, Peder

“…Formaldehyde is a ubiquitous indoor air pollutant that is classified as “Carcinogenic to humans (Group 1)” (IARC, Formaldehyde, 2-butoxyethanol and…”
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Recent trend in risk assessment of formaldehyde exposures from indoor air by Nielsen, Gunnar Damgård, Larsen, Søren Thor, Wolkoff, Peder

“…Studies about formaldehyde (FA) published since the guideline of 0.1 mg/m 3 by the World Health Organization (WHO) in 2010 have been evaluated; critical…”
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Airway effects of repeated exposures to ozone-initiated limonene oxidation products as model of indoor air mixtures by Wolkoff, Peder, Clausen, Per Axel, Larsen, Søren Thor, Hammer, Maria, Nielsen, Gunnar Damgård

“…► Mice were repeatedly exposed to ozone-initiated limonene oxidation products. ► Sensory irritation is the key effect. ► Repeated exposures did not cause a…”
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Sensory irritation: Risk assessment approaches by Nielsen, Gunnar Damgård, Wolkoff, Peder, Alarie, Yves

“…Irritation of eyes and upper airways—sensory irritation—is commonly used as a parameter for setting occupational exposure limits and is a common complaint in…”
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Acute airway effects of airborne formaldehyde in sensitized and non-sensitized mice housed in a dry or humid environment by Larsen, Søren Thor, Wolkoff, Peder, Hammer, Maria, Kofoed-Sørensen, Vivi, Clausen, Per Axel, Nielsen, Gunnar Damgård

“…We investigated the role of air humidity and allergic sensitization on the acute airway response to inhaled formaldehyde (FA) vapor. Mice were sensitized to…”
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Adjuvant and Inflammatory Effects in Mice After Subchronic Inhalation of Allergen and Ozone-Initiated Limonene Reaction Products by Hansen, Jitka Stilund, Nielsen, Gunnar Damgård, Sørli, Jorid Birkelund, Clausen, Per Axel, Wolkoff, Peder, Larsen, Søren Thor

“…Inhalation of ozone (O 3 ), a highly toxic environmental pollutant, produces airway inflammation and exacerbates asthma. However, in indoor air, O 3 reacts…”
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Adjuvant effects of inhaled mono- 2 -ethylhexyl phthalate in BALB/cJ mice by Hansen, Jitka Stilund, Larsen, Søren Thor, Poulsen, Lars K, Nielsen, Gunnar Damgård

“…Abstract Phthalates, including di(2-ethylhexyl) phthalate (DEHP), are widely used and have been linked with the development of wheezing and asthma. The main…”
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Chemical and biological evaluation of a reaction mixture of R-(+)-limonene/ozone : Formation of strong airway irritants by Clausen, Per Axel, Wilkins, Cornelius Ken, Wolkoff, Peder, Nielsen, Gunnar Damgård

“…The airway irritation of a reaction mixture of R-(+)-limonene and ozone was evaluated by a mouse bioassay in which sensory irritation, bronchoconstriction and…”
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In vivo Biology and Toxicology of Fullerenes and Their Derivatives by Nielsen, Gunnar Damgård, Roursgaard, Martin, Jensen, Keld Alstrup, Poulsen, Steen Seier, Larsen, Søren Thor

“…:  Fullerenes represent a group of nanoparticles discovered in 1985. They are spherical molecules consisting entirely of carbon atoms (Cx) to which side chains…”
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Development of sensitisation or tolerance following repeated OVA inhalation in BALB/cJ mice. Dose-dependency and modulation by the Al(OH) 3 adjuvant by Clausen, Susanne Knoth, Bergqvist, Mette, Poulsen, Lars K, Poulsen, Otto Melchior, Nielsen, Gunnar Damgård

“…Anthropogenically induced exposures may, due to their adjuvant effect, promote development of sensitisation to commonly occurring aeroallergens. No generally…”
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Does Lipophilicity Per Se Induce Adjuvant Effects? Methyl Palmitate as Model Substance Does Not Affect Ovalbumin Sensitization by Stilund Hansen, Jitka, Thor Larsen, Søren, Poulsen, Lars K., Damgård Nielsen, Gunnar

“…Anthopogenically introduced substances and pollutants are suspected to promote senstitization and development of allergic airway diseases, that is, acting as…”
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Airway inflammation and adjuvant effect after repeated airborne exposures to di-(2-ethylhexyl)phthalate and ovalbumin in BALB/c mice by Larsen, Søren Thor, Hansen, Jitka Stilund, Hansen, Erik Wind, Clausen, Per Axel, Nielsen, Gunnar Damgård

“…Abstract Background Epidemiological studies have suggested an association between exposure to phthalate plasticizers, including di-(2-ethylhexyl)phthalate…”
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Background, approaches and recent trends for setting health-based occupational exposure limits: A minireview by Nielsen, Gunnar Damgård, Øvrebø, Steinar

“…The setting of occupational exposure limits (OELs) are founded in occupational medicine and the predictive toxicological testing, resulting in…”
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The adjuvant effect of di-(2-ethylhexyl) phthalate is mediated through a PPARα-independent mechanism by Larsen, Søren Thor, Nielsen, Gunnar Damgård

“…Previous studies in BALB/c mice revealed an adjuvant effect of di-(2-ethylhexyl) phthalate (DEHP) to simultaneously administered ovalbumin. DEHP is the most…”
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Comment to “Di-(2-ethylhexyl) phthalate is without adjuvant effect in mice on ovalbumin” [Toxicology 244 (2008) 231–241] by Hansen, Jitka Stilund, Larsen, Søren Thor, Nielsen, Gunnar Damgård

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Di-(2-ethylhexyl) phthalate possesses an adjuvant effect in a subcutaneous injection model with BALB/c mice by Thor Larsen, Søren, My Lund, Rikke, Damgård Nielsen, Gunnar, Thygesen, Peter, Melchior Poulsen, Otto

“…The prevalence of allergic airway diseases is rapidly increasing in Western Europe and North America and the introduction of anthropogenic chemicals may…”
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Possible Mechanisms for the Respiratory Tract Effects of Noncarcinogenic indoor-climate Pollutants and Bases for Their Risk Assessment by Nielsen, Gunnar Damgård, Alarie, Yves, Poulsen, Otto Melchior, Nexø, Bjørn Andersen

“…This review outlines the effects of pollutants on the lungs. Mechanisms and effects relevant to the assessment of indoor-air risk are especially dealt with…”
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Chemical and Biological Evaluation of Building Material Emissions. I. A Screening Procedure based on a Closed Emission System by Nielsen, Gunnar Damgard, Hansen, Lea Frimann, Hammer, Maria, Vejrup, Karl Ventzel, Wolkoff, Peder

“…Abstract only…”
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Neurological Effects of White Spirit: Contribution of Animal Studies during a 30‐Year Period by Nielsen, Gunnar Damgård, Lund, Søren Peter, Ladefoged, Ole

“…: Numerous studies have suggested that long‐term occupational exposure to white spirit may cause chronic toxic encephalopathy (WHO 1996). This review…”
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